Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
26184-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NaDC3 Fusion Protein Ag24182 (161-229 aa encoded by BC035966)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SLFGQKEVR KDPSQESEEN TAAVRRNGLH TVPTEMQFLA STEAKDHPGE TEVPLDLPAD SRKEDEYRRN (161-229 aa encoded by BC035966)
Target Information
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: hNaDC3; mNaDC3; Na(+)-coupled carboxylate transporter 3; Na(+)/dicarboxylate cotransporter 3; NaC3; NaDC-3; SLC13A3; sodium-dependent high affinity dicarboxylate transporter 3; Sodium-dependent high-affinity dicarboxylate transporter 2; Solute carrier family 13 member 3
Gene Aliases: NaDC-3; NADC3; SDCT2; SLC13A3
UniProt ID: (Human) Q8WWT9, (Mouse) Q91Y63
Entrez Gene ID: (Human) 64849, (Mouse) 114644
citrate transmembrane transporter activity
succinate transmembrane transporter activity
L-aspartate transmembrane transporter activity
high-affinity sodium:dicarboxylate symporter activity
sodium:dicarboxylate symporter activity
transporter activity
dicarboxylic acid transmembrane transporter activity
organic acid:sodium symporter activity
symporter activity
transporter
secondary carrier transporter
sodium ion transport
citrate transport
succinate transmembrane transport
L-aspartate transmembrane transport
organic acid transmembrane transport
transport
ion transport
dicarboxylic acid transport
succinate transport
aspartate transport
tricarboxylic acid transmembrane transport
sodium ion transmembrane transport
transmembrane transport
anion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support