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Product Details
NORB-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on rat NORBIN protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: M-Sema F-associating protein of 75 kDa; minisatellite 10ae detected by probe MMS10; Neurite outgrowth-related protein from the rat brain; Neurochondrin; neurochondrin-1; neurochondrin-2; Norbin
Gene Aliases: AU042419; KIAA0607; mKIAA0607; MMS10-AE; Ms10ae; NCDN; Norbin; Sfap75
UniProt ID: (Human) Q9UBB6, (Mouse) Q9Z0E0, (Rat) O35095
Entrez Gene ID: (Human) 23154, (Mouse) 26562, (Rat) 89791
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