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Neuroligin 2 Antibody (PA5-89727) in WB
Western blot analysis of Neuroligin 2 in extracts of Mouse heart. Samples were incubated with Neuroligin 2 Polyclonal antibody (Product # PA5-89727) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-89727
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 15-180 of human NLGN2 (NP_0658461)
Conjugate
Form
Liquid
Concentration
2.3 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805747
Product Specific Information
Immunogen sequence: QRGGGGPGGG APGGPGLGLG SLGEERFPVV NTAYGRVRGV RRELNNEILG PVVQFLGVPY ATPPLGARRF QPPEAPASWP GVRNATTLPP ACPQNLHGAL PAIMLPVWFT DNLEAAATYV QNQSEDCLYL NLYVPTEDGP LTKKRDEATL NPPDTDIRDP GKKPVM; Positive Samples: Mouse heart; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, presynaptic cell membrane, synapse
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neuroligin-2; ortholog of human and rat neuroligin 2 NLGN2
Gene Aliases: Kiaa1366; NL2; Nlgn2
UniProt ID: (Mouse) Q69ZK9
Entrez Gene ID: (Mouse) 216856
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cell adhesion
neuron cell-cell adhesion
synapse assembly
jump response
positive regulation of cell proliferation
sensory perception of pain
positive regulation of insulin secretion
positive regulation of synaptic transmission, GABAergic
social behavior
protein localization to synapse
locomotory exploration behavior
modulation of synaptic transmission
synapse organization
neuromuscular process controlling balance
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
positive regulation of dendritic spine development
terminal button organization
postsynaptic membrane assembly
presynaptic membrane assembly
gephyrin clustering involved in postsynaptic density assembly
postsynaptic density protein 95 clustering
positive regulation of inhibitory postsynaptic potential
insulin metabolic process
positive regulation of protein localization to synapse
positive regulation of t-SNARE clustering
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
positive regulation of synaptic vesicle clustering
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