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Alomone Labs, LTD
Neuroligin 2 (extracellular) Polyclonal Antibody
FIGURE: 1 / 4
Neuroligin 2 (extracellular) Antibody (ANR-036-200UL) in ICC/IF
Expression of NLGN2 in rat PC12 cells - Cell surface detection of NLGN2 in intact living rat PC12 cells. A. Extracellular staining of cells using Anti-Neuroligin 2 (extracellular) Antibody (#ANR-036), (1:25), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Nuclear staining using DAPI as the counterstain (blue). C. Merged images of A and B.
Product Details
ANR-036-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)DLGPRAYDRFPGDS, corresponding to amino acid residues 657-670 of rat NLGN2, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neuroligin-2; ortholog of human and rat neuroligin 2 NLGN2
Gene Aliases: Kiaa1366; NL2; Nlgn2
UniProt ID: (Rat) Q62888, (Mouse) Q69ZK9
Entrez Gene ID: (Rat) 117096, (Mouse) 216856
thigmotaxis
regulation of respiratory gaseous exchange by neurological system process
cell adhesion
neuron cell-cell adhesion
synapse assembly
jump response
metabolic process
sensory perception of pain
positive regulation of synaptic transmission, GABAergic
social behavior
protein localization to synapse
locomotory exploration behavior
modulation of synaptic transmission
synapse organization
neuromuscular process controlling balance
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
terminal button organization
postsynaptic membrane assembly
presynaptic membrane assembly
gephyrin clustering involved in postsynaptic density assembly
postsynaptic density protein 95 clustering
positive regulation of inhibitory postsynaptic potential
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
positive regulation of cell proliferation
positive regulation of insulin secretion
positive regulation of dendritic spine development
insulin metabolic process
positive regulation of protein localization to synapse
positive regulation of t-SNARE clustering
positive regulation of synaptic vesicle clustering
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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