Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Specificity: a 125 kD nucleoplasmic protein (AND-1, acidic nucleoplasmic DNA-binding protein) in Xenopus. Immunolocalization studies showed a dispersed, finely granular distribution pattern throughout the nucleoplasm.
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CRM1/XPO1 protein; exportin 1 (CRM1 homolog)
Gene Aliases: crm1; exportin-1; XELAEV_18028477mg; Xpo; xpo1
Entrez Gene ID: (Xenopus) 399087
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support