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Immunogen sequence: HGLDQQDLRYL RAQLQRKLHL LSRP
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 92%.
Nurim is an inner nuclear membrane (INM) protein that is tightly associated with the inner nuclear membrane. It was first isolated in a visual screen for nuclear envelope-localizing proteins. In subcellular fractionation, nurim remained extremely tightly bound to nuclear fractions. Unlike the known nuclear envelope (NE) membrane proteins, it is neither associated with nuclear pores, nor targeted like lamin-associated membrane proteins suggesting its localization to NE by a distinct mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAAP-285E11.8; Nuclear envelope membrane protein; Nuclear rim protein; Nurim
Gene Aliases: NRM; NRM29; UNQ555/PRO1112
UniProt ID: (Human) Q8IXM6
Entrez Gene ID: (Human) 11270
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