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Product Details
22851-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OFD1 Fusion Protein Ag18898 (1-305 aa encoded by BC096344)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognize all the isoforms of OFD1. The 43 kDa is isoform 2. The ~80 kDa band is unknown.
Immunogen sequence: MMAQSNMFT VADVLSQDEL RKKLYQTFKD RGILDTLKTQ LRNQLIHELM HPVLSGELQP RSISVEGSSL LIGASNSLVA DHLQRCGYEY SLSVFFPESG LAKEKVFTMQ DLLQLIKINP TSSLYKSLVS GSDKENQKGF LMHFLKELAE YHQAKESCNM ETQTSSTFNR DSLAEKLQLI DDQFADAYPQ RIKFESLEIK LNEYKREIEE QLRAEMCQKL KFFKDTEIAK IKMEAKKKYE KELTMFQNDF EKACQAKSEA LVLREKSTLE RIHKHQEIET KEIYAQRQLL LKDMDLLRGR EAELKQ (1-305 aa encoded by B C096344)
Target Information
This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Centriole and centriolar satellite protein OFD1; Oral-facial-digital syndrome 1 protein; Protein 71-7A
Gene Aliases: 71-7A; CXorf5; JBTS10; OFD1; RP23; SGBS2
UniProt ID: (Human) O75665
Entrez Gene ID: (Human) 8481
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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