Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RNLSGSLAA IQEEMGAYGY EDLQQRVMAL EARLHACAQK LGCGKLTGVS NPITVRAMGS RFGSWMTDTM APSADSRVWY MDGYYKGRRV LEFRTLGDFI KGQNFIQHLL PQPWAGTGHV VYNGSLFYNK YQSNVVVKYH FRSRSVLVQR SLPGAGYNNT FPYSWGGFSD MDFMVDESGL WAVYTTNQNA GNIVVSRLDP HTLEVMRSWD TGYPKRSAGE AFMICGVLYV TNSHLAGAKV YFAYFTNTSS YEYTDVPFHN QYSHISMLDY NPRERALYTW NNGHQVLYNV TLFHVISTSG DP (154-454 aa encoded by BC011361)
Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: neuronal olfactomedin related ER localized protein 2; noelin 2; Noelin-2; Olfactomedin-2
Gene Aliases: A030009A06Rik; NOE2; NOELIN2; NOELIN2_V1; OlfC; OLFM2
UniProt ID: (Human) O95897, (Rat) Q568Y7, (Mouse) Q8BM13
Entrez Gene ID: (Human) 93145, (Rat) 313783, (Mouse) 244723
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