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OLFM2 Antibody (PA5-48087) in WB
Western blot analysis of OLFM2 in human cortex and hippocampus tissue. Samples were incubated in OLFM2 polyclonal antibody (Product # PA5-48087) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. A specific band was detected for Olfactomedin‚2/Noelin‚2 at approximately 54 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-48087
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant human Olfactomedin-2/Noelin-2 Gln21-Pro454
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609871
Product Specific Information
In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse (rm) Olfactomedin-1 is observed and less than 5% cross-reactivity with recombinant human Olfactomedin-4 and rmOlfactomedin-L3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuronal olfactomedin related ER localized protein 2; noelin 2; Noelin-2; Olfactomedin-2
Gene Aliases: NOE2; NOELIN2; NOELIN2_V1; OlfC; OLFM2
UniProt ID: (Human) O95897
Entrez Gene ID: (Human) 93145
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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