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OLIG2 Antibody (PA5-117535) in WB
Western Blot analysis of OLIG2 using OLIG2 Polyclonal Antibody (Product # PA5-117535) at 2 µg/mL. Positive WB detected in Recombinant protein. Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa
Product Details
PA5-117535
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Zebrafish Oligodendrocyte lineage transcription factor 2 protein (150-273aa)
Conjugate
Form
Liquid
Concentration
2.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2902164
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); olig-2; Oligo2 antibody; Oligodendrocyte specific bHLH transcription factor 2; Protein kinase C-binding protein 2 (PRKCBP2)
Gene Aliases: wu:fc64g09
Entrez Gene ID: (Zebrafish) 325288
neuron migration
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
neuroblast fate determination
glial cell fate determination
oligodendrocyte development
ventral spinal cord interneuron differentiation
spinal cord motor neuron cell fate specification
spinal cord motor neuron differentiation
abducens nucleus development
facial nucleus development
oligodendrocyte cell fate specification
neuron differentiation
myelination
neuron development
oligodendrocyte differentiation
positive regulation of neurogenesis
dopaminergic neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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