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OSMR Antibody (MA5-23921) in ICC/IF
Immunocytochemistry analysis of OSMR in immersion fixed D3 mouse embryonic stem cell line. Samples were incubated in OSMR monoclonal antibody (Product # MA5-23921) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 493-conjugated Anti-Rat IgG Secondary Antibody (green) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
Product Details
MA5-23921
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
118125
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OSM R beta Glu24-Leu738
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610119
Product Specific Information
In Western blots, no cross-reactivity with recombinant human (rh) CLC, rhCNTF, rhOSM, recombinant mouse (rm) CT-1, rmIL-6, rmIL-11, or rmLIF is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB; Interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin receptor; oncostatin-M specific receptor subunit beta; Oncostatin-M-specific receptor subunit beta
Gene Aliases: Osmr; OSMRB
UniProt ID: (Mouse) O70458
Entrez Gene ID: (Mouse) 18414
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