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This antibody is predicted to react with bovine, human and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
The product of this gene is a member of the OTU superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating enzyme OTUB1; FLJ20113; FLJ40710; MGC111158; MGC4584; OTU domain-containing ubiquitin aldehyde-binding protein 1; otubain 1; Otubain-1; Ubiquitin thioesterase OTUB1; Ubiquitin-specific-processing protease OTUB1
Gene Aliases: AI850305; Otub1
UniProt ID: (Mouse) Q7TQI3
Entrez Gene ID: (Mouse) 107260
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