Proteintech

Occludin Polyclonal Antibody

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Antibody Testing Data (10)

Occludin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

Occludin Antibody (27260-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed Caco-2 cells using Occludin antibody (Product # 27260-1-AP) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Occludin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Occludin Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

27260-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 244 publications 244 publications

Immunohistochemistry (IHC)

View 41 publications 41 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:800

View 74 publications 74 publications

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Not applicable (N/A)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Occludin Fusion Protein Ag26173 (360-522 aa encoded by BC029886)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VDDFRQPRY SSGGNFETPS KRAPAKGRAG RSKRTEQDHY ETDYTTGGES CDELEEDWIR EYPPITSDQQ RQLYKRNFDT GLQEYKSLQS ELDEINKELS RLDKELDDYR EESEEYMAAA DEYNRLKQVK GSADYKSKKN HCKQLKSKLS HIKKMVGDYD RQKT (360-522 aa encoded by B C029886)

Target Information

Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution. Overall structural features of the occludin protein are highly conserved in all the species examined. Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.

Clinical and experimental hypertension (New York, N.Y. : 1993)

Li W,Li SG,Li L,Yang LJ,Li ZS,Li X,Ye AY,Xiong Y,Zhang Y,Xiong YY

Sun Dec 31 00:00:00 EST 2023

Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury.

Molecular neurobiology

Xie C,Wang Y,Wang J,Xu Y,Liu H,Guo J,Zhu L

Sun Jan 01 00:00:00 EST 2023

Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.

Nutrients

Xie Z,Zhang G,Liu R,Wang Y,Tsapieva AN,Zhang L,Han J

Tue Apr 04 00:00:00 EDT 2023

Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.

iScience

Wang M,Li L,Qian J,Wang N,Bao J,Lu J,Chen F,Li Y,Zhang Y,Yan F

Fri Apr 21 00:00:00 EDT 2023

Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation.

Acta pharmacologica Sinica

Zha ZX,Lin Y,Wang KX,Zhang YL,Li D,Xu GQ,Xu QM,Liu YL

Sun Jan 01 00:00:00 EST 2023

The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.

Microvascular research

Zhang C,Cao X,Wang H,Li Z,Zhang Y

Sat Jul 01 00:00:00 EDT 2023

Disordered gut microbiota promotes atrial fibrillation by aggravated conduction disturbance and unbalanced linoleic acid/SIRT1 signaling.

Biochemical pharmacology

Fang C,Zuo K,Liu Z,Liu Y,Liu L,Wang Y,Yin X,Li J,Liu X,Chen M,Yang X

Sat Jul 01 00:00:00 EDT 2023

Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).

Small (Weinheim an der Bergstrasse, Germany)

Huang Q,Yang Y,Zhu Y,Chen Q,Zhao T,Xiao Z,Wang M,Song X,Jiang Y,Yang Y,Zhang J,Xiao Y,Nan Y,Wu W,Ai K

Mon May 01 00:00:00 EDT 2023

Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).

Small (Weinheim an der Bergstrasse, Germany)

Huang Q,Yang Y,Zhu Y,Chen Q,Zhao T,Xiao Z,Wang M,Song X,Jiang Y,Yang Y,Zhang J,Xiao Y,Nan Y,Wu W,Ai K

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.

International immunopharmacology

Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J

Mon May 01 00:00:00 EDT 2023

A novel model of subretinal edema induced by DL-alpha aminoadipic acid.

Experimental eye research

Xie Z,Wu X,Cheng R,Huang J,Wang X,Shi Q,Xu B,Paulus YM,Yuan S,Liu Q

Wed Mar 01 00:00:00 EST 2023

Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.

Chemico-biological interactions

Wang C,Shang H,Zhang S,Wang X,Liu D,Shen M,Li N,Jiang Y,Wei K,Zhu R

Sat Jul 01 00:00:00 EDT 2023

Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.

Chemico-biological interactions

Wang C,Shang H,Zhang S,Wang X,Liu D,Shen M,Li N,Jiang Y,Wei K,Zhu R

Sat Jul 01 00:00:00 EDT 2023

Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.

Chemico-biological interactions

Wang C,Shang H,Zhang S,Wang X,Liu D,Shen M,Li N,Jiang Y,Wei K,Zhu R

Sat Jul 01 00:00:00 EDT 2023

PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury.

Experimental neurology

Acosta CH,Clemons GA,Citadin CT,Carr WC,Udo MSB,Tesic V,Sanicola HW,Freelin AH,Toms JB,Jordan JD,Guthikonda B,Rodgers KM,Wu CY,Lee RH,Lin HW

Tue Aug 01 00:00:00 EDT 2023

FTO-dependent m⁶A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.

Nature communications

Li B,Xi W,Bai Y,Liu X,Zhang Y,Li L,Bian L,Liu C,Tang Y,Shen L,Yang L,Gu X,Xie J,Zhou Z,Wang Y,Yu X,Wang J,Chao J,Han B,Yao H

Mon Jan 30 00:00:00 EST 2023

Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.

Nutrients

Zhao S,Zhang Y,Ding H,Hu S,Wu X,Ma A,Ma Y

Tue Feb 28 00:00:00 EST 2023

Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.

Frontiers in immunology

Ding S,Cheng Y,Azad MAK,Dong H,He J,Huang P,Kong X

Tue Mar 07 00:00:00 EST 2023

Comprehensive analysis of cuproptosis-related genes in immune infiltration and diagnosis in ulcerative colitis.

Frontiers in immunology

Huang J,Zhang J,Wang F,Zhang B,Tang X

Wed Feb 15 00:00:00 EST 2023

Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.

Journal of agricultural and food chemistry

Xu D,Zhuang L,Gao S,Ma H,Cheng J,Liu J,Liu D,Fu S,Hu G

Wed Nov 23 00:00:00 EST 2022

Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.

Journal of agricultural and food chemistry

Wang Q,Wang C,Tian W,Qiu Z,Song M,Cao Y,Xiao J

Wed Feb 23 00:00:00 EST 2022

Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.

Journal of agricultural and food chemistry

Wang Q,Wang C,Tian W,Qiu Z,Song M,Cao Y,Xiao J

Wed Feb 23 00:00:00 EST 2022

Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.

Cutaneous and ocular toxicology

Li M,Tian M,Jiang X,Liu Y,Wang Y,Li Y

Wed Jun 01 00:00:00 EDT 2022

Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.

Evidence-based complementary and alternative medicine : eCAM

Niu S,Jing M,Wen J,Wei S,Li H,Li X,Ma X,Zhao Y

Thu Oct 06 00:00:00 EDT 2022

Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.

Animal science journal = Nihon chikusan Gakkaiho

Guo Z,Chen X,Huang Z,Chen D,Yu J,Yan H,Chen H,He J,Zheng P,Luo Y,Yu B

Thu Jun 16 00:00:00 EDT 2022

Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.

International journal of biological macromolecules

Cai G,Wu C,Mao N,Song Z,Yu L,Zhu T,Peng S,Yang Y,Liu Z,Wang D

Sat Oct 01 00:00:00 EDT 2022

The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.

Frontiers in nutrition

Dai YJ,Liu WB,Abasubong KP,Zhang DD,Li XF,Xiao K,Wang X,Jiang GZ

Sat Jul 16 00:00:00 EDT 2022

The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.

Frontiers in nutrition

Dai YJ,Liu WB,Abasubong KP,Zhang DD,Li XF,Xiao K,Wang X,Jiang GZ

Sat Jul 16 00:00:00 EDT 2022

Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.

Molecular medicine reports

Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S

Thu Dec 01 00:00:00 EST 2022

Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.

Molecular medicine reports

Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S

Thu Dec 01 00:00:00 EST 2022

Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.

Molecular medicine reports

Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S

Thu Dec 01 00:00:00 EST 2022

Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.

Molecular medicine reports

Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S

Thu Dec 01 00:00:00 EST 2022

LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.

Cellular and molecular life sciences : CMLS

Wang S,Qian Z,Ge X,Li C,Xue M,Liang K,Ma R,Ouyang L,Zheng L,Jing J,Cao S,Zhang Y,Yang Y,Chen Y,Ma J,Yao B

Tue Feb 01 00:00:00 EST 2022

Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.

Journal of animal science and biotechnology

Shan Q,Liu N,Wang X,Zhu Y,Yin J,Wang J

Fri Sep 09 00:00:00 EDT 2022

Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.

Journal of neuroinflammation

Hu H,Yang X,He Y,Duan C,Sun N

Wed Aug 24 00:00:00 EDT 2022

Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.

Journal of neuroinflammation

Hu H,Yang X,He Y,Duan C,Sun N

Wed Aug 24 00:00:00 EDT 2022

An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.

Cell reports

Li Y,Wei JY,Liu H,Wang KJ,Jin SN,Su ZK,Wang HJ,Shi JX,Li B,Shang DS,Fang WG,Qin XX,Zhao WD,Chen YH

Tue Apr 12 00:00:00 EDT 2022

Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.

Journal of drug targeting

Han D,Li F,Zhang H,Ji C,Shu Q,Wang C,Ni H,Zhu Y,Wang S

Fri Apr 01 00:00:00 EDT 2022

Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.

Microbiology spectrum

Liu Z,Jiang Z,Zhang Z,Liu T,Fan Y,Liu T,Peng N

Wed Aug 31 00:00:00 EDT 2022

Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.

Food research international (Ottawa, Ont.)

Pan WJ,Shi LL,Ren YR,Yao CY,Lu YM,Chen Y

Thu Dec 01 00:00:00 EST 2022

Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.

The Journal of nutritional biochemistry

Yu C,Liu S,Niu Y,Fu L

Thu Sep 01 00:00:00 EDT 2022

Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.

International journal of biological macromolecules

Kai L,Zong X,Jiang Q,Lu Z,Wang F,Wang Y,Wang T,Jin M

Sat Jan 15 00:00:00 EST 2022

Mo₃Se₄ nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.

Redox biology

Guo H,Guo H,Xie Y,Chen Y,Lu C,Yang Z,Zhu Y,Ouyang Y,Zhang Y,Wang X

Sat Oct 01 00:00:00 EDT 2022

Mo₃Se₄ nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.

Redox biology

Guo H,Guo H,Xie Y,Chen Y,Lu C,Yang Z,Zhu Y,Ouyang Y,Zhang Y,Wang X

Sat Oct 01 00:00:00 EDT 2022

Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.

Frontiers in cardiovascular medicine

Song Q,Chen P,Wu SJ,Chen Y,Zhang Y

Mon May 02 00:00:00 EDT 2022

The underlying rationality of Chinese medicine herb pair Coptis chinensis and Dolomiaea souliei: From the perspective of metabolomics and intestinal function.

Journal of ethnopharmacology

Wang T,Zhang C,Li H,Zhou R,Ye X,Yang Y,He K

Tue May 10 00:00:00 EDT 2022

Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.

Frontiers in immunology

Yang Y,Zheng X,Wang Y,Tan X,Zou H,Feng S,Zhang H,Zhang Z,He J,Cui B,Zhang X,Wu Z,Dong M,Cheng W,Tao S,Wei H

Mon May 02 00:00:00 EDT 2022

Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.

Experimental and therapeutic medicine

Yang HY,Liang ZH,Xie JL,Wu Q,Qin YY,Zhang SY,Tang GD

Fri Apr 01 00:00:00 EDT 2022

Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.

Frontiers in nutrition

Wang W,Li Y,Han G,Li A,Kong X

Tue Aug 02 00:00:00 EDT 2022

Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.

Frontiers in nutrition

Wang W,Li Y,Han G,Li A,Kong X

Tue Aug 02 00:00:00 EDT 2022

Staphylococcal Enterotoxin A Induces Intestinal Barrier Dysfunction and Activates NLRP3 Inflammasome via NF-κB/MAPK Signaling Pathways in Mice.

Toxins

Liu C,Chi K,Yang M,Guo N

Sat Jan 01 00:00:00 EST 2022

Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.

Animal biotechnology

Liu A,Chen X,Huang Z,Chen D,Yu B,Chen H,He J,Yan H,Zheng P,Yu J,Luo Y

Wed Jun 01 00:00:00 EDT 2022

Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Sun P,Zhang C,Huang Y,Yang J,Zhou F,Zeng J,Lin Y

Wed Jun 01 00:00:00 EDT 2022

Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.

Journal of neurochemistry

Meng D,Yang M,Hu L,Liu T,Zhang H,Sun X,Wang X,Chen Y,Jin Y,Liu R

Thu Dec 01 00:00:00 EST 2022

Chromogranin A-derived peptide CGA47-66 protects against septic brain injury by reducing blood-brain barrier damage through the PI3K/AKT pathway.

Biochemical and biophysical research communications

Wang F,Zeng Y,Liu X,Cao J,Kang S,Zhou W,Chen X,Liu J,Zhang D

Sat May 21 00:00:00 EDT 2022

JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.

Brain research bulletin

Zhong X,Chen Z,Wang Y,Mao M,Deng Y,Shi M,Xu Y,Chen L,Cao W

Sat Oct 15 00:00:00 EDT 2022

Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.

Oxidative medicine and cellular longevity

Gao S,Zhou L,Lu J,Fang Y,Wu H,Xu W,Pan Y,Wang J,Wang X,Zhang J,Shao A

Tue Apr 05 00:00:00 EDT 2022

miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.

Annals of translational medicine

Xiao W,Jiang Z,Wan W,Pan W,Xu J

Sun May 01 00:00:00 EDT 2022

Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.

Experimental neurology

Xie Y,Zou X,Han J,Zhang Z,Feng Z,Ouyang Q,Hua S,Liu Z,Li C,Cai Y,Zou Y,Tang Y,Jiang X

Fri Jul 01 00:00:00 EDT 2022

Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.

Experimental neurology

Xie Y,Zou X,Han J,Zhang Z,Feng Z,Ouyang Q,Hua S,Liu Z,Li C,Cai Y,Zou Y,Tang Y,Jiang X

Fri Jul 01 00:00:00 EDT 2022

De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.

Neuroscience

Wei H,Zhen L,Wang S,Zhang Y,Wang K,Jia P,Zhang Y,Wu Z,Yang Q,Hou W,Lv J,Zhang P

Sat Jan 15 00:00:00 EST 2022

Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.

Frontiers in immunology

Wang K,Chen D,Yu B,He J,Mao X,Huang Z,Yan H,Wu A,Luo Y,Zheng P,Yu J,Luo J

Thu Sep 08 00:00:00 EDT 2022

Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.

Frontiers in immunology

Wang K,Chen D,Yu B,He J,Mao X,Huang Z,Yan H,Wu A,Luo Y,Zheng P,Yu J,Luo J

Thu Sep 08 00:00:00 EDT 2022

Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.

Journal of agricultural and food chemistry

Chen Y,Zhang H,Li Y,Ji S,Jia P,Wang T

Wed Oct 26 00:00:00 EDT 2022

The Anti-Obesity and Anti-Inflammatory Capabilities of Pterostilbene and its Colonic Metabolite Pinostilbene Protect against Tight Junction Disruption from Western Diet Feeding.

Molecular nutrition & food research

Koh YC,Lin SJ,Nagabhushanam K,Ho CT,Pan MH

Mon Aug 01 00:00:00 EDT 2022

The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.

PloS one

Das B,Rabalais J,Kozan P,Lu T,Durali N,Okamoto K,McGeough MD,Lee BJ,Barrett KE,Marchelletta R,Sivagnanam M

Tue Jul 12 00:00:00 EDT 2022

Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Xia S,Chen L,Li Z,Li Y,Zhou Y,Sun S,Su Y,Xu X,Shao J,Zhang Z,Kong D,Zhang F,Zheng S

Thu Dec 01 00:00:00 EST 2022

Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Xia S,Chen L,Li Z,Li Y,Zhou Y,Sun S,Su Y,Xu X,Shao J,Zhang Z,Kong D,Zhang F,Zheng S

Thu Dec 01 00:00:00 EST 2022

TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.

Journal of neuroinflammation

Yan J,Zhang Y,Wang L,Li Z,Tang S,Wang Y,Gu N,Sun X,Li L

Sat Dec 03 00:00:00 EST 2022

The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.

Frontiers in nutrition

He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L

Sat Jul 16 00:00:00 EDT 2022

Effects of fecal stream deprivation on human intestinal barrier after loop ileostomy.

Journal of gastroenterology and hepatology

Li X,Ma H,Sun Y,Li T,Wang C,Zheng H,Chen G,Du G,Ji G,Yang H,Xiao W,Qiu Y

Wed Jun 01 00:00:00 EDT 2022

Effects of fecal stream deprivation on human intestinal barrier after loop ileostomy.

Journal of gastroenterology and hepatology

Li X,Ma H,Sun Y,Li T,Wang C,Zheng H,Chen G,Du G,Ji G,Yang H,Xiao W,Qiu Y

Wed Jun 01 00:00:00 EDT 2022

Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.

EBioMedicine

Hou Z,Ding Q,Li Y,Zhao Z,Yan F,Li Y,Wang X,Xu J,Chen W,Wu G,Ruan X,Zhao L

Mon Aug 01 00:00:00 EDT 2022

Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.

Journal of extracellular vesicles

Yu X,Bai Y,Han B,Ju M,Tang T,Shen L,Li M,Yang L,Zhang Z,Hu G,Chao J,Zhang Y,Yao H

Sat Jan 01 00:00:00 EST 2022

Fu brick tea alleviates high fat induced non-alcoholic fatty liver disease by remodeling the gut microbiota and liver metabolism.

Frontiers in nutrition

Tang Y,Chen B,Huang X,He X,Yi J,Zhao H,Tian F,Liu Y,Liu B

Fri Nov 03 00:00:00 EDT 2023

Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.

PloS one

Sun J,Zhang W

Wed May 04 00:00:00 EDT 2022

Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.

Journal of animal science and biotechnology

Cui C,Wu C,Wang J,Ma Z,Zheng X,Zhu P,Wang N,Zhu Y,Guan W,Chen F

Fri Oct 14 00:00:00 EDT 2022

MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.

Biochemical pharmacology

Gu H,Li Y,Cui X,Cao H,Hou Z,Ti Y,Liu D,Gao J,Wang Y,Wen P

Sat Jan 01 00:00:00 EST 2022

Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.

Molecular nutrition & food research

Chen L,Liu D,Mao M,Liu W,Wang Y,Liang Y,Cao W,Zhong X

Tue Nov 01 00:00:00 EDT 2022

Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.

Molecular nutrition & food research

Chen L,Liu D,Mao M,Liu W,Wang Y,Liang Y,Cao W,Zhong X

Tue Nov 01 00:00:00 EDT 2022

CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.

Vascular pharmacology

Mu J,Que Y,Li X,Zhou F,Jin L,Li S,Zhu C

Tue Feb 01 00:00:00 EST 2022

Zearalenone disturbs the reproductive-immune axis in pigs: the role of gut microbial metabolites.

Microbiome

Wang S,Fu W,Zhao X,Chang X,Liu H,Zhou L,Li J,Cheng R,Wu X,Li X,Sun C

Mon Dec 19 00:00:00 EST 2022

Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhan L,Pu J,Zheng J,Hang S,Pang L,Dai M,Ji C

Fri Apr 01 00:00:00 EDT 2022

Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.

Animal biotechnology

Wei C,Chen X,Chen D,He J,Zheng P,Chen H,Yan H,Yu B,Luo Y,Huang Z

Thu Dec 01 00:00:00 EST 2022

Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.

The Science of the total environment

Zhou GX,Liu WB,Dai LM,Zhu HL,Xiong YW,Li DX,Xu DX,Wang H

Tue Mar 01 00:00:00 EST 2022

Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.

The Science of the total environment

Zhou GX,Liu WB,Dai LM,Zhu HL,Xiong YW,Li DX,Xu DX,Wang H

Tue Mar 01 00:00:00 EST 2022

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice.

Chemosphere

Shan S,Zhang Y,Zhao H,Zeng T,Zhao X

Fri Jul 01 00:00:00 EDT 2022

Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.

Psychopharmacology

Lin S,Li Q,Xu Z,Chen Z,Tao Y,Tong Y,Wang T,Chen S,Wang P

Tue Nov 01 00:00:00 EDT 2022

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.

AMB Express

Rehman AU,Khan AI,Xin Y,Liang W

Sat Sep 03 00:00:00 EDT 2022

Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Liping Y,Xinglin YU,Chao Z,Pu C,Xiaohua D

Sat Oct 01 00:00:00 EDT 2022

Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

Liping Y,Xinglin YU,Chao Z,Pu C,Xiaohua D

Sat Oct 01 00:00:00 EDT 2022

Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation.

Journal of Crohn's & colitis

Liu X,Ren X,Zhou L,Liu K,Deng L,Qing Q,Li J,Zhi F,Li M

Thu Aug 04 00:00:00 EDT 2022

Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhan L,Zheng J,Meng J,Fu D,Pang L,Ji C

Tue Nov 01 00:00:00 EDT 2022

Effect of TRAF6 in acute pancreatitis-induced intestinal barrier injury via TLR4/NF-κB signal pathway.

Tissue & cell

Wei B,Wu Q,Yang X,Lai C,Su Z,Liang Z

Wed Jun 01 00:00:00 EDT 2022

Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.

Veterinary microbiology

Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J

Tue Mar 01 00:00:00 EST 2022

A yes-associated protein 1- Notch1 receptor positive feedback loop promotes breast cancer lung metastasis by attenuating the bone morphogenetic protein 4-SMAD family member 1/5 signaling.

Carcinogenesis

Zhao L,Lei J,Gu S,Zhang Y,Jing X,Wang L,Zhang L,Ning Q,Luo M,Qi Y,Zhao X,Shao S

Sat Dec 31 00:00:00 EST 2022

Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.

Nutrients

Xu RC,Miao WT,Xu JY,Xu WX,Liu MR,Ding ST,Jian YX,Lei YH,Yan N,Liu HD

Fri Oct 07 00:00:00 EDT 2022

Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.

Journal of agricultural and food chemistry

Wang Y,Liu J,Liu H,Liu L,Gao X,Tong Y,Song S,Yan C

Wed Jun 01 00:00:00 EDT 2022

Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.

Journal of agricultural and food chemistry

Wang Y,Liu J,Liu H,Liu L,Gao X,Tong Y,Song S,Yan C

Wed Jun 01 00:00:00 EDT 2022

Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.

Frontiers in physiology

Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B

Sat Jul 16 00:00:00 EDT 2022

Strains producing different short-chain fatty acids alleviate DSS-induced ulcerative colitis by regulating intestinal microecology.

Food & function

Yang S,Shang J,Liu L,Tang Z,Meng X

Mon Nov 28 00:00:00 EST 2022

Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.

Food & function

Song L,Wu T,Zhang L,Wan J,Ruan Z

Wed Apr 20 00:00:00 EDT 2022

Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.

Journal of agricultural and food chemistry

Huang T,Che Q,Chen X,Chen D,Yu B,He J,Chen H,Yan H,Zheng P,Luo Y,Huang Z

Wed Jun 22 00:00:00 EDT 2022

Vinegar reduced renal calcium oxalate stones by regulating acetate metabolism in gut microbiota and crystal adhesion in rats.

International urology and nephrology

Liu Y,Jin X,Ma Y,Sun Q,Li H,Wang K

Sat Oct 01 00:00:00 EDT 2022

Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.

Oxidative medicine and cellular longevity

Wang L,Wang J

Fri Dec 30 00:00:00 EST 2022

Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.

Oxidative medicine and cellular longevity

Wang L,Wang J

Fri Dec 30 00:00:00 EST 2022

P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.

Aging and disease

Huang L,Chen Y,Liu R,Li B,Fei X,Li X,Liu G,Li Y,Xu B,Fang W

Sat Oct 01 00:00:00 EDT 2022

Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways.

Molecules (Basel, Switzerland)

Zhang B,Wei X,Ding M,Luo Z,Tan X,Zheng Z

Thu Dec 15 00:00:00 EST 2022

Aerobic exercise improves intestinal mucosal barrier dysfunction through TLR4/MyD88/NF-κB signaling pathway in diabetic rats.

Biochemical and biophysical research communications

Li J,Liu X,Wu Y,Ji W,Tian Q,Li S

Sat Dec 17 00:00:00 EST 2022

Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.

Acta pharmacologica Sinica

Li HL,Wei YY,Li XH,Zhang SS,Zhang RT,Li JH,Ma BW,Shao SB,Lv ZW,Ruan H,Zhou HG,Yang C

Fri Apr 01 00:00:00 EDT 2022

Heat Stress Impairs Maternal Endometrial Integrity and Results in Embryo Implantation Failure by Regulating Transport-Related Gene Expression in Tongcheng Pigs.

Biomolecules

Lian W,Gao D,Huang C,Zhong Q,Hua R,Lei M

Wed Mar 02 00:00:00 EST 2022

Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.

Evidence-based complementary and alternative medicine : eCAM

Peng H,Jin L,Zhang Q,Shen Y,Wang Z,Zhou F,Yu Q

Sat Jul 16 00:00:00 EDT 2022

Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.

Nutrients

Suzuki T,Sato Y,Kadoya S,Takahashi T,Otomo M,Kobayashi H,Aoki K,Kantake M,Sugiyama M,Ferraris RP

Sun Aug 07 00:00:00 EDT 2022

Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.

Nutrients

Suzuki T,Sato Y,Kadoya S,Takahashi T,Otomo M,Kobayashi H,Aoki K,Kantake M,Sugiyama M,Ferraris RP

Sun Aug 07 00:00:00 EDT 2022

Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.

Bioengineered

Yu Y,Bian Y,Shi JX,Gu Y,Yuan DP,Yu B,Shi L,Dou DH

Wed Jun 01 00:00:00 EDT 2022

Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells.

Advanced biology

Hinman SS,Massaro A,Wang Y,Sims CE,Kim R,Allbritton NL

Tue Nov 01 00:00:00 EDT 2022

Cassane diterpenoid ameliorates dextran sulfate sodium-induced experimental colitis by regulating gut microbiota and suppressing tryptophan metabolism.

Frontiers in immunology

Liu T,Ning Z,Liu P,Gao H

Tue Feb 07 00:00:00 EST 2023

Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.

Journal of orthopaedic translation

Zhang YW,Cao MM,Li YJ,Lu PP,Dai GC,Zhang M,Wang H,Rui YF

Tue Nov 01 00:00:00 EDT 2022

Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function.

Journal of orthopaedic translation

Zhang YW,Cao MM,Li YJ,Lu PP,Dai GC,Zhang M,Wang H,Rui YF

Tue Nov 01 00:00:00 EDT 2022

Periplaneta americana Extract Pretreatment Alleviates Oxidative Stress and Inflammation and Increases the Abundance of Gut Akkermansia muciniphila in Diquat-Induced Mice.

Antioxidants (Basel, Switzerland)

Lu S,Xu S,Chen L,Deng Y,Feng J

Tue Sep 13 00:00:00 EDT 2022

Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice: mechanistic insights.

Food & function

Xia P,Hou T,Ma M,Li S,Jin H,Luo X,Li J,Geng F,Li B

Mon May 23 00:00:00 EDT 2022

SARS-CoV-2 productively infects human brain microvascular endothelial cells.

Journal of neuroinflammation

Yang RC,Huang K,Zhang HP,Li L,Zhang YF,Tan C,Chen HC,Jin ML,Wang XR

Wed Jun 15 00:00:00 EDT 2022

Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.

Microbiology spectrum

Huang B,Gui M,Ni Z,He Y,Zhao J,Peng J,Lin J

Wed Dec 21 00:00:00 EST 2022

A signature of circadian rhythm genes in driving anaplastic thyroid carcinoma malignant progression.

Cellular signalling

Xu T,Jin T,Lu X,Pan Z,Tan Z,Zheng C,Liu Y,Hu X,Ba L,Ren H,Chen J,Zhu C,Ge M,Huang P

Fri Jul 01 00:00:00 EDT 2022

Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.

Molecular nutrition & food research

Guo X,Xu Y,Geng R,Qiu J,He X

Fri Apr 01 00:00:00 EDT 2022

Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice.

Frontiers in microbiology

Hu Y,Jin X,Gao F,Lin T,Zhu H,Hou X,Yin Y,Kan S,Chen D

Tue Aug 23 00:00:00 EDT 2022

Age-dependent effects of a high-fat diet combined with dietary advanced glycation end products on cognitive function and protection with voluntary exercise.

Food & function

Luo L,Li R,Wang G,Chen J,Chen L,Qin LQ,Yu Z,Wan Z

Wed Apr 20 00:00:00 EDT 2022

Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.

Molecules (Basel, Switzerland)

Liu J,Li B,Liu J,Qiu F,Diao Y,Lei Y,Liu J,Zhang W

Tue Aug 16 00:00:00 EDT 2022

Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota.

Journal of agricultural and food chemistry

Huang Z,Yang W,Wang X,Guo F,Cheng Y,Cao L,Zhu W,Sun Y,Xiong H

Wed Apr 27 00:00:00 EDT 2022

Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.

Journal of cellular physiology

Guo J,Nie J,Chen Z,Wang X,Hu H,Xu J,Lu J,Ma L,Ji H,Yuan J,Xu B

Sat Oct 01 00:00:00 EDT 2022

Polystyrene nanoplastics promote CHIP-mediated degradation of tight junction proteins by activating IRE1α/XBP1s pathway in mouse Sertoli cells.

Ecotoxicology and environmental safety

Hu R,Yao C,Li Y,Qu J,Yu S,Han Y,Chen G,Tang J,Wei H

Thu Dec 15 00:00:00 EST 2022

Polysaccharides from Artocarpus heterophyllus Lam. (jackfruit) pulp improves intestinal barrier functions of high fat diet-induced obese rats.

Frontiers in nutrition

Zeng S,Cao J,Chen Y,Li C,Wu G,Zhu K,Chen X,Xu F,Liu Q,Tan L

Mon Sep 18 00:00:00 EDT 2023

Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.

Andrologia

Huang T,Zhou Y,Lu X,Tang C,Ren C,Bao X,Deng Z,Cao X,Zou J,Zhang Q,Ma B

Tue Feb 01 00:00:00 EST 2022

Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.

International journal of biological macromolecules

Zhang K,Lian S,Shen X,Zhao X,Zhao W,Li C

Tue May 31 00:00:00 EDT 2022

NU9056, a KAT 5 Inhibitor, Treatment Alleviates Brain Dysfunction by Inhibiting NLRP3 Inflammasome Activation, Affecting Gut Microbiota, and Derived Metabolites in LPS-Treated Mice.

Frontiers in nutrition

Chen L,Qing W,Yi Z,Lin G,Peng Q,Zhou F

Sat Jul 31 00:00:00 EDT 2021

High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.

Environmental toxicology

Li C,Shi L,Wang Y,Peng C,Wu L,Zhang Y,Du Z

Thu Jul 01 00:00:00 EDT 2021

High-fat diet exacerbates lead-induced blood-brain barrier disruption by disrupting tight junction integrity.

Environmental toxicology

Li C,Shi L,Wang Y,Peng C,Wu L,Zhang Y,Du Z

Thu Jul 01 00:00:00 EDT 2021

Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.

Acta biochimica et biophysica Sinica

Wang S,Deng W,Li F,Chen YE,Wang PU

Tue Oct 12 00:00:00 EDT 2021

Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.

Acta cirurgica brasileira

Xu J,Zhan T,Zheng W,Huang YK,Chen K,Zhang XH,Ren P,Huang X

Fri Jan 29 00:00:00 EST 2021

Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.

Frontiers in immunology

Chu BX,Li YN,Liu N,Yuan LX,Chen SY,Zhu YH,Wang JF

Mon Feb 14 00:00:00 EST 2022

Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.

Stem cells international

Tian X,Cao H,Wu L,Zheng W,Yuan M,Li X,Song H,Shen Z

Thu Jul 22 00:00:00 EDT 2021

Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.

Frontiers in pharmacology

Gong S,Ma H,Zheng F,Huang J,Zhang Y,Yu B,Li F,Kou J

Wed Dec 15 00:00:00 EST 2021

Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.

Cells

Fu J,Wang T,Xiao X,Cheng Y,Wang F,Jin M,Wang Y,Zong X

Tue Mar 02 00:00:00 EST 2021

Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.

Food & function

Bai X,Fu R,Duan Z,Liu Y,Zhu C,Fan D

Wed Apr 07 00:00:00 EDT 2021

Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.

Scientific reports

Jin Z,Chen K,Zhou Z,Peng W,Liu W

Wed Jul 21 00:00:00 EDT 2021

Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.

Brain sciences

Fu J,Li L,Huo D,Zhi S,Yang R,Yang B,Xu B,Zhang T,Dai M,Tan C,Chen H,Wang X

Fri Jan 08 00:00:00 EST 2021

Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats.

Environmental science and pollution research international

Li S,Wang Q,Yu H,Yang L,Sun Y,Xu N,Wang N,Lei Z,Hou J,Jin Y,Zhang H,Li L,Xu F,Zhang L

Wed Sep 01 00:00:00 EDT 2021

Acrolein Induces Systemic Coagulopathy via Autophagy-dependent Secretion of von Willebrand Factor in Mice after Traumatic Brain Injury.

Neuroscience bulletin

Cui W,Wu X,Feng D,Luo J,Shi Y,Guo W,Liu H,Wang Q,Wang L,Ge S,Qu Y

Sun Aug 01 00:00:00 EDT 2021

Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chu Y,Zhu Y,Zhang Y,Liu X,Guo Y,Chang L,Yun X,Wei Z,Xia Y,Dai Y

Sat May 01 00:00:00 EDT 2021

Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chu Y,Zhu Y,Zhang Y,Liu X,Guo Y,Chang L,Yun X,Wei Z,Xia Y,Dai Y

Sat May 01 00:00:00 EDT 2021

Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.

Food & function

Jin Y,Zhai Z,Jia H,Lai J,Si X,Wu Z

Mon Aug 02 00:00:00 EDT 2021

Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway.

Chemico-biological interactions

Shu A,Du Q,Chen J,Gao Y,Zhu Y,Lv G,Lu J,Chen Y,Xu H

Fri Oct 01 00:00:00 EDT 2021

Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway.

Chemico-biological interactions

Shu A,Du Q,Chen J,Gao Y,Zhu Y,Lv G,Lu J,Chen Y,Xu H

Fri Oct 01 00:00:00 EDT 2021

Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NF-κB pathway through microbiota-gut-brain axis.

Acta pharmaceutica Sinica. B

Zhao Z,Li F,Ning J,Peng R,Shang J,Liu H,Shang M,Bao XQ,Zhang D

Wed Sep 01 00:00:00 EDT 2021

Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.

International journal of biological macromolecules

Liu C,Hua H,Zhu H,Cheng Y,Guo Y,Yao W,Qian H

Tue Aug 31 00:00:00 EDT 2021

Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Cao YY,Wang ZH,Xu QC,Chen Q,Wang Z,Lu WH

Thu Jul 01 00:00:00 EDT 2021

Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.

Food & function

Zhang Z,Xue Z,Yang H,Zhao F,Liu C,Chen J,Lu S,Zou Z,Zhou Y,Zhang X

Mon Mar 01 00:00:00 EST 2021

Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.

Open life sciences

Yu H,He B,Han X,Yan T

Tue Sep 14 00:00:00 EDT 2021

Dietary Acrylamide Intake Alters Gut Microbiota in Mice and Increases Its Susceptibility to Salmonella Typhimurium Infection.

Foods (Basel, Switzerland)

Wang Z,Liu H,Liu J,Ren X,Song G,Xia X,Qin N

Fri Dec 03 00:00:00 EST 2021

A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.

Acta pharmaceutica Sinica. B

Gao C,Xu Y,Liang Z,Wang Y,Shang Q,Zhang S,Wang C,Ni M,Wu D,Huang Z,Pang T

Thu Jul 01 00:00:00 EDT 2021

LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.

Inflammatory bowel diseases

Su X,Wei J,Qi H,Jin M,Zhang Q,Zhang Y,Zhang C,Yang R

Tue Jul 27 00:00:00 EDT 2021

LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.

Inflammatory bowel diseases

Su X,Wei J,Qi H,Jin M,Zhang Q,Zhang Y,Zhang C,Yang R

Tue Jul 27 00:00:00 EDT 2021

Chronic restraint stress induced changes in colonic homeostasis-related indexes and tryptophan-kynurenine metabolism in rats.

Journal of proteomics

Li CC,Gan L,Tan Y,Yan MZ,Liu XM,Chang Q,Pan RL

Sun May 30 00:00:00 EDT 2021

Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets.

Animal nutrition (Zhongguo xu mu shou yi xue hui)

Xie C,Zhang Y,Niu K,Liang X,Wang H,Shan J,Wu X

Wed Sep 01 00:00:00 EDT 2021

Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.

Journal of cellular physiology

Chang Y,Deng Q,Zhang Z,Zhao H,Tang J,Chen X,Liu G,Tian G,Cai J,Jia G

Thu Apr 01 00:00:00 EDT 2021

HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.

Cancer letters

Pan Z,Fang Q,Li L,Zhang Y,Xu T,Liu Y,Zheng X,Tan Z,Huang P,Ge M

Wed Mar 31 00:00:00 EDT 2021

Melatonin as Immune Potentiator for Enhancing Subunit Vaccine Efficacy against Bovine Viral Diarrhea Virus.

Vaccines

Wang YX,Yang GH,Zhang LL,Wang J,Wang JF

Sat Sep 18 00:00:00 EDT 2021

Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.

Food & function

Liao M,Zhang Y,Qiu Y,Wu Z,Zhong Z,Zeng X,Zeng Y,Xiong L,Wen Y,Liu R

Tue Oct 19 00:00:00 EDT 2021

Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.

Foods (Basel, Switzerland)

Guo F,Tsao R,Li C,Wang X,Zhang H,Jiang L,Sun Y,Xiong H

Thu Nov 11 00:00:00 EST 2021

JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.

Frontiers in immunology

Chen L,Zhong X,Cao W,Mao M,Li W,Yang H,Li M,Shi M,Zhang Y,Deng Y,Zu X,Liu J

Fri Jul 02 00:00:00 EDT 2021

JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.

Frontiers in immunology

Chen L,Zhong X,Cao W,Mao M,Li W,Yang H,Li M,Shi M,Zhang Y,Deng Y,Zu X,Liu J

Fri Jul 02 00:00:00 EDT 2021

Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.

Cell death discovery

Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z

Tue Mar 23 00:00:00 EDT 2021

Gut Microbial Dysbiosis Associated with Type 2 Diabetes Aggravates Acute Ischemic Stroke.

mSystems

Chen X,Wu Q,Gao X,Wang H,Zhu J,Xia G,He Y,Song W,Xu K

Tue Dec 21 00:00:00 EST 2021

Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.

Chinese medicine

Li S,Zheng M,Zhang Z,Peng H,Dai W,Liu J

Tue Feb 16 00:00:00 EST 2021

Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.

Microorganisms

Chen S,Li Y,Chu B,Yuan L,Liu N,Zhu Y,Wang J

Fri Sep 17 00:00:00 EDT 2021

Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.

Microorganisms

Chen S,Li Y,Chu B,Yuan L,Liu N,Zhu Y,Wang J

Fri Sep 17 00:00:00 EDT 2021

Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.

Food research international (Ottawa, Ont.)

Bai X,Fu R,Duan Z,Wang P,Zhu C,Fan D

Sun Aug 01 00:00:00 EDT 2021

Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.

Environmental toxicology and pharmacology

Chen Z,Wu Y,Wang B,Fang J,Gan C,Sang C,Dun Z,Luosang T,Wang Q,Zeren D,Xiong T

Sun Aug 01 00:00:00 EDT 2021

BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.

Mediators of inflammation

Wan Y,Song M,Xie X,Chen Z,Gao Z,Wu X,Huang R,Chen M

Thu Mar 31 00:00:00 EDT 2022

BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.

Mediators of inflammation

Wan Y,Song M,Xie X,Chen Z,Gao Z,Wu X,Huang R,Chen M

Thu Mar 31 00:00:00 EDT 2022

Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.

Food & function

Niu X,Shang H,Chen S,Chen R,Huang J,Miao Y,Cui W,Wang H,Sha Z,Peng D,Zhu R

Thu Jan 07 00:00:00 EST 2021

Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.

Frontiers in veterinary science

Wang D,Zhou L,Zhou H,Hou G

Sat Jun 12 00:00:00 EDT 2021

Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.

Neurochemical research

Tang B,Song M,Xie X,Le D,Tu Q,Wu X,Chen M

Wed Sep 01 00:00:00 EDT 2021

Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.

Neurochemistry international

Xin J,Ma X,Chen W,Zhou W,Dong H,Wang Z,Ji F

Fri Oct 01 00:00:00 EDT 2021

Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.

Journal of animal science and biotechnology

Chen Y,Zhang H,Chen Y,Jia P,Ji S,Zhang Y,Wang T

Thu Jun 10 00:00:00 EDT 2021

Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.

International journal of biological macromolecules

Zong X,Cheng Y,Xiao X,Fu J,Wang F,Lu Z,Wang Y,Jin M

Sat Jul 31 00:00:00 EDT 2021

Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.

Veterinary research

Zhao J,Wan S,Sun N,Sun P,Sun Y,Khan A,Guo J,Zheng X,Fan K,Yin W,Li H

Wed Jun 23 00:00:00 EDT 2021

The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.

Frontiers in immunology

Zhou Y,Duan L,Zeng Y,Niu L,Pu Y,Jacobs JP,Chang C,Wang J,Khalique A,Pan K,Fang J,Jing B,Zeng D,Ni X

Mon Feb 07 00:00:00 EST 2022

Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.

Molecular nutrition & food research

Liu H,Zhan Q,Miao X,Xia X,Yang G,Peng X,Yan C

Mon Feb 01 00:00:00 EST 2021

Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.

Molecular nutrition & food research

Liu H,Zhan Q,Miao X,Xia X,Yang G,Peng X,Yan C

Mon Feb 01 00:00:00 EST 2021

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.

Pharmacological research

Wang Y,Guan X,Gao CL,Ruan W,Zhao S,Kai G,Li F,Pang T

Thu Jul 01 00:00:00 EDT 2021

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.

Pharmacological research

Wang Y,Guan X,Gao CL,Ruan W,Zhao S,Kai G,Li F,Pang T

Thu Jul 01 00:00:00 EDT 2021

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.

Pharmacological research

Wang Y,Guan X,Gao CL,Ruan W,Zhao S,Kai G,Li F,Pang T

Thu Jul 01 00:00:00 EDT 2021

Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.

Pharmacological research

Wang Y,Guan X,Gao CL,Ruan W,Zhao S,Kai G,Li F,Pang T

Thu Jul 01 00:00:00 EDT 2021

Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice.

Frontiers in nutrition

Huang F,Liu X,Xu S,Hu S,Wang S,Shi D,Wang K,Wang Z,Lin Q,Li S,Zhao S,Jin K,Wang C,Chen L,Wang F

Sun May 01 00:00:00 EDT 2022

Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice.

Frontiers in nutrition

Huang F,Liu X,Xu S,Hu S,Wang S,Shi D,Wang K,Wang Z,Lin Q,Li S,Zhao S,Jin K,Wang C,Chen L,Wang F

Sun May 01 00:00:00 EDT 2022

Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.

International journal of biological macromolecules

Zong X,Xiao X,Kai L,Cheng Y,Fu J,Xu W,Wang Y,Zhao K,Jin M

Fri Jan 15 00:00:00 EST 2021

Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.

Pharmacological research

Zhang CL,Wang HL,Li PC,Hong CD,Chen AQ,Qiu YM,Zeng AP,Zhou YF,Hu B,Li YN

Wed Sep 01 00:00:00 EDT 2021

AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.

Frontiers in pharmacology

Ye R,Wang C,Sun P,Bai S,Zhao L

Tue Jun 29 00:00:00 EDT 2021

AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.

Frontiers in pharmacology

Ye R,Wang C,Sun P,Bai S,Zhao L

Tue Jun 29 00:00:00 EDT 2021

AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.

Frontiers in pharmacology

Ye R,Wang C,Sun P,Bai S,Zhao L

Tue Jun 29 00:00:00 EDT 2021

Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Wei YY,Fan YM,Ga Y,Zhang YN,Han JC,Hao ZH

Mon Nov 01 00:00:00 EDT 2021

Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Wei YY,Fan YM,Ga Y,Zhang YN,Han JC,Hao ZH

Mon Nov 01 00:00:00 EDT 2021

Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2.

Endocrinology

Fu Y,Wei Y,Zhou Y,Wu H,Hong Y,Long C,Wang J,Wu Y,Wu S,Shen L,Wei G

Fri Oct 01 00:00:00 EDT 2021

Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2.

Endocrinology

Fu Y,Wei Y,Zhou Y,Wu H,Hong Y,Long C,Wang J,Wu Y,Wu S,Shen L,Wei G

Fri Oct 01 00:00:00 EDT 2021

C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.

Free radical biology & medicine

Xue S,Tang H,Zhao G,Fang C,Shen Y,Yan D,Yuan Y,Fu W,Shi Z,Tang X,Guo D

Sat May 01 00:00:00 EDT 2021

C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.

Free radical biology & medicine

Xue S,Tang H,Zhao G,Fang C,Shen Y,Yan D,Yuan Y,Fu W,Shi Z,Tang X,Guo D

Sat May 01 00:00:00 EDT 2021

Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis.

Microbiome

Zhao Z,Ning J,Bao XQ,Shang M,Ma J,Li G,Zhang D

Wed Nov 17 00:00:00 EST 2021

MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.

Biomaterials

Song M,Zhang S,Tao Z,Li J,Shi Y,Xiong Y,Zhang W,Liu C,Chen S

Mon Nov 01 00:00:00 EDT 2021

Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.

Frontiers in pharmacology

Shi A,Li T,Zheng Y,Song Y,Wang H,Wang N,Dong L,Shi H

Tue Jul 20 00:00:00 EDT 2021

Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.

Journal of animal science and biotechnology

Zou T,Yang J,Guo X,He Q,Wang Z,You J

Wed Mar 10 00:00:00 EST 2021

Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.

Annals of translational medicine

Li L,Zhou C,Li T,Xiao W,Yu M,Yang H

Mon Mar 01 00:00:00 EST 2021

Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.

Annals of translational medicine

Li L,Zhou C,Li T,Xiao W,Yu M,Yang H

Mon Mar 01 00:00:00 EST 2021

Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.

Journal of animal science and biotechnology

Gao R,Tian S,Wang J,Zhu W

Wed Aug 11 00:00:00 EDT 2021

KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1.

Cell death & disease

Hua Q,Sun Z,Liu Y,Shen X,Zhao W,Zhu X,Xu P

Wed Sep 22 00:00:00 EDT 2021

l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.

Journal of agricultural and food chemistry

Wang Y,Sun J,Xue L,Liu J,Nie C,Fan M,Qian H,Zhang D,Ying H,Li Y,Wang L

Wed Mar 31 00:00:00 EDT 2021

MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.

Journal of gastrointestinal oncology

Qi Y,Fang Q,Li Q,Ding H,Shu Q,Hu Y,Xin W,Fang L

Sun Aug 01 00:00:00 EDT 2021

Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.

International immunopharmacology

Kong L,Ma Y,Wang Z,Liu N,Ma G,Liu C,Shi R,Du G

Sat May 01 00:00:00 EDT 2021

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.

Frontiers in pharmacology

Fan XD,Yao MJ,Yang B,Han X,Zhang YH,Wang GR,Li P,Xu L,Liu JX

Sat Nov 20 00:00:00 EST 2021

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.

Frontiers in pharmacology

Fan XD,Yao MJ,Yang B,Han X,Zhang YH,Wang GR,Li P,Xu L,Liu JX

Sat Nov 20 00:00:00 EST 2021

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.

Frontiers in pharmacology

Fan XD,Yao MJ,Yang B,Han X,Zhang YH,Wang GR,Li P,Xu L,Liu JX

Sat Nov 20 00:00:00 EST 2021

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway-Dependent Cerebral Microvascular Protection.

Frontiers in pharmacology

Fan XD,Yao MJ,Yang B,Han X,Zhang YH,Wang GR,Li P,Xu L,Liu JX

Sat Nov 20 00:00:00 EST 2021

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.

Frontiers in immunology

Qu Y,Li X,Xu F,Zhao S,Wu X,Wang Y,Xie J

Mon Oct 25 00:00:00 EDT 2021

Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice.

Food & function

Cai G,Wu Y,Wusiman A,Gu P,Mao N,Xu S,Zhu T,Feng Z,Liu Z,Wang D

Mon Aug 02 00:00:00 EDT 2021

Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.

Brain research bulletin

Liu C,Cheng Y,Guo Y,Qian H

Wed Sep 01 00:00:00 EDT 2021

Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.

Food & function

Wu T,Wang X,Xiong H,Deng Z,Peng X,Xiao L,Jiang L,Sun Y

Mon Nov 29 00:00:00 EST 2021

Gut Microbiota Was Involved in the Process of Liver Injury During Intra-Abdominal Hypertension.

Frontiers in physiology

Zhao Z,Guo Z,Yin Z,Qiu Y,Zhou B

Tue Dec 28 00:00:00 EST 2021

Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.

Environmental pollution (Barking, Essex : 1987)

Xie X,Zhou J,Hu L,Shu R,Zhang M,Xiong Z,Wu F,Fu Z

Wed Dec 01 00:00:00 EST 2021

RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.

Molecular therapy oncolytics

Shen S,Yang C,Liu X,Zheng J,Liu Y,Liu L,Ma J,Ma T,An P,Lin Y,Cai H,Wang D,Li Z,Zhao L,Xue Y

Fri Jun 26 00:00:00 EDT 2020

RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway.

Molecular therapy oncolytics

Shen S,Yang C,Liu X,Zheng J,Liu Y,Liu L,Ma J,Ma T,An P,Lin Y,Cai H,Wang D,Li Z,Zhao L,Xue Y

Fri Jun 26 00:00:00 EDT 2020

Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.

Burns & trauma

Liu X,Chen Y,You B,Peng Y,Chen Y,Yang Z,Zhang Y,Chen J

Wed Apr 20 00:00:00 EDT 2022

microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.

Journal of neurochemistry

Wu J,He J,Tian X,Luo Y,Zhong J,Zhang H,Li H,Cen B,Jiang T,Sun X

Mon Jun 01 00:00:00 EDT 2020

microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.

Journal of neurochemistry

Wu J,He J,Tian X,Luo Y,Zhong J,Zhang H,Li H,Cen B,Jiang T,Sun X

Mon Jun 01 00:00:00 EDT 2020

Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.

Bioscience reports

Liu Y,Zhang S,Li X,Liu E,Wang X,Zhou Q,Ye J,Wang JZ

Fri Feb 28 00:00:00 EST 2020

Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.

Drug design, development and therapy

Zou X,Wang Y,Wang Y,Yang J,Guo H,Cai Z

Tue Sep 21 00:00:00 EDT 2021

Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.

Reproductive toxicology (Elmsford, N.Y.)

Wang S,Chen Q,Zhang Y,Zheng F,Xue T,Ge X,Ma R,Li X,Wu R,Liang K,Qian Z,Ge Y,Ma J,Yao B

Tue Dec 01 00:00:00 EST 2020

NUDT21 Suppresses Breast Cancer Tumorigenesis Through Regulating CPSF6 Expression.

Cancer management and research

Wang BJ,Liu DC,Guo QY,Han XW,Bi XM,Wang H,Wu ZS,Wu WY

Thu Apr 14 00:00:00 EDT 2022

Pyrroloquinoline Quinone Alleviates Jejunal Mucosal Barrier Function Damage and Regulates Colonic Microbiota in Piglets Challenged With Enterotoxigenic Escherichia coli.

Frontiers in microbiology

Huang C,Ming D,Wang W,Wang Z,Hu Y,Ma X,Wang F

Mon Sep 28 00:00:00 EDT 2020

Dysfunction of pulmonary epithelial tight junction induced by silicon dioxide nanoparticles via the ROS/ERK pathway and protein degradation.

Chemosphere

Liu Y,Wei H,Tang J,Yuan J,Wu M,Yao C,Hosoi K,Yu S,Zhao X,Han Y,Chen G

Tue Sep 01 00:00:00 EDT 2020

Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.

Acta pharmacologica Sinica

Zhou YQ,Liu DQ,Chen SP,Chen N,Sun J,Wang XM,Cao F,Tian YK,Ye DW

Sat Aug 01 00:00:00 EDT 2020

Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.

Frontiers in cellular neuroscience

Xie J,Hong E,Ding B,Jiang W,Zheng S,Xie Z,Tian D,Chen Y

Tue Dec 08 00:00:00 EST 2020

1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.

Frontiers in pharmacology

Yi X,Xu C,Huang P,Zhang L,Qing T,Li J,Wang C,Zeng T,Lu J,Han Z

Mon Sep 28 00:00:00 EDT 2020

O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.

EMBO reports

Bagdonaite I,Pallesen EM,Ye Z,Vakhrushev SY,Marinova IN,Nielsen MI,Kramer SH,Pedersen SF,Joshi HJ,Bennett EP,Dabelsteen S,Wandall HH

Thu Jun 04 00:00:00 EDT 2020

Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.

Journal of ethnopharmacology

Su H,Zhang C,Zou X,Lu F,Zeng Y,Guan H,Ren Y,Yuan F,Xu L,Zhang M,Dong H

Wed Mar 25 00:00:00 EDT 2020

Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.

The Science of the total environment

Jiang Z,Mu W,Yang Y,Sun M,Liu Y,Gao Z,Li J,Gu P,Wang H,Lu Y,Ba Q,Wang H

Fri Nov 20 00:00:00 EST 2020

Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.

The Science of the total environment

Jiang Z,Mu W,Yang Y,Sun M,Liu Y,Gao Z,Li J,Gu P,Wang H,Lu Y,Ba Q,Wang H

Fri Nov 20 00:00:00 EST 2020

Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.

The Science of the total environment

Jiang Z,Mu W,Yang Y,Sun M,Liu Y,Gao Z,Li J,Gu P,Wang H,Lu Y,Ba Q,Wang H

Fri Nov 20 00:00:00 EST 2020

Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.

The Science of the total environment

Jiang Z,Mu W,Yang Y,Sun M,Liu Y,Gao Z,Li J,Gu P,Wang H,Lu Y,Ba Q,Wang H

Fri Nov 20 00:00:00 EST 2020

Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.

Chemico-biological interactions

Jiang YP,Ye RJ,Yang JM,Liu N,Zhang WJ,Ma L,Sun T,Niu JG,Zheng P,Yu JQ

Sun Jan 05 00:00:00 EST 2020

Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.

Journal of agricultural and food chemistry

Li S,Ma B,Wang J,Peng H,Zheng M,Dai W,Liu J

Thu Nov 19 00:00:00 EST 2020

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Toxicology letters

Liu Y,Tang J,Yuan J,Yao C,Hosoi K,Han Y,Yu S,Wei H,Chen G

Sat Oct 10 00:00:00 EDT 2020

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Toxicology letters

Liu Y,Tang J,Yuan J,Yao C,Hosoi K,Han Y,Yu S,Wei H,Chen G

Sat Oct 10 00:00:00 EDT 2020

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Toxicology letters

Liu Y,Tang J,Yuan J,Yao C,Hosoi K,Han Y,Yu S,Wei H,Chen G

Sat Oct 10 00:00:00 EDT 2020

Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways.

Toxicology letters

Liu Y,Tang J,Yuan J,Yao C,Hosoi K,Han Y,Yu S,Wei H,Chen G

Sat Oct 10 00:00:00 EDT 2020

Self-recovery study of the adverse effects of fluoride on small intestine: Involvement of pyroptosis induced inflammation.

The Science of the total environment

Li M,Wang J,Wu P,Manthari RK,Zhao Y,Li W,Wang J

Tue Nov 10 00:00:00 EST 2020

Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-B Pathway.

The American journal of Chinese medicine

Wu J,Yang CL,Sha YK,Wu Y,Liu ZY,Yuan ZH,Sun ZL

Fri Sep 04 00:00:00 EDT 2020

Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.

Journal of affective disorders

Xiao Q,Shu R,Wu C,Tong Y,Xiong Z,Zhou J,Yu C,Xie X,Fu Z

Sun Nov 01 00:00:00 EDT 2020

Protective effects of FGF10 on neurovascular unit in a rat model of neonatal hypoxic-ischemic brain injury.

Experimental neurology

Fang M,Jiang S,Zhu J,Fu X,Hu Y,Pan S,Jiang H,Lin J,Yuan J,Li P,Lin Z

Thu Oct 01 00:00:00 EDT 2020

Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.

Translational stroke research

Wu J,He J,Tian X,Zhong J,Li H,Sun X

Sat Aug 01 00:00:00 EDT 2020

Exposure to dibutyl phthalate impairs lipid metabolism and causes inflammation via disturbing microbiota-related gut-liver axis.

Acta biochimica et biophysica Sinica

Xiong Z,Zeng Y,Zhou J,Shu R,Xie X,Fu Z

Tue Dec 29 00:00:00 EST 2020

Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.

Journal of hazardous materials

Wu J,Lai X,Cui G,Chen Q,Liu J,Kang Y,Zhang Y,Feng X,Hu C,Shao L

Sun Nov 15 00:00:00 EST 2020

Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.

Journal of hazardous materials

Wu J,Lai X,Cui G,Chen Q,Liu J,Kang Y,Zhang Y,Feng X,Hu C,Shao L

Sun Nov 15 00:00:00 EST 2020

Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.

Journal of hazardous materials

Wu J,Lai X,Cui G,Chen Q,Liu J,Kang Y,Zhang Y,Feng X,Hu C,Shao L

Sun Nov 15 00:00:00 EST 2020

Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles.

Journal of hazardous materials

Wu J,Lai X,Cui G,Chen Q,Liu J,Kang Y,Zhang Y,Feng X,Hu C,Shao L

Sun Nov 15 00:00:00 EST 2020

Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.

Neuroscience

Lu Z,Zhang D,Cui K,Fu X,Man J,Lu H,Yu L,Gao Y,Liu X,Liao L,Li X,Liu C,Zhang Y,Zhang Z,Wang J

Tue Jan 21 00:00:00 EST 2020

Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.

Veterinary research

Chu B,Zhu Y,Su J,Xia B,Zou Y,Nie J,Zhang W,Wang J

Wed Aug 05 00:00:00 EDT 2020

Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.

Veterinary research

Chu B,Zhu Y,Su J,Xia B,Zou Y,Nie J,Zhang W,Wang J

Wed Aug 05 00:00:00 EDT 2020

Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.

Veterinary research

Chu B,Zhu Y,Su J,Xia B,Zou Y,Nie J,Zhang W,Wang J

Wed Aug 05 00:00:00 EDT 2020

Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.

Veterinary research

Chu B,Zhu Y,Su J,Xia B,Zou Y,Nie J,Zhang W,Wang J

Wed Aug 05 00:00:00 EDT 2020

Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.

Redox biology

Jia Y,Cui R,Wang C,Feng Y,Li Z,Tong Y,Qu K,Liu C,Zhang J

Fri May 01 00:00:00 EDT 2020

Significance of gastrointestinal tract in the therapeutic mechanisms of exercise in depression: Synchronism between brain and intestine through GBA.

Progress in neuro-psychopharmacology & biological psychiatry

Liu Y,Xu F,Liu S,Liu G,Yang X,Gao W,Fan K,Zhao H,Ma J

Sun Dec 20 00:00:00 EST 2020

ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.

Journal of cellular physiology

Zhu D,Zhou J,Zhao J,Jiang G,Zhang X,Zhang Y,Dong M

Sat Jun 01 00:00:00 EDT 2019

ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.

Journal of cellular physiology

Zhu D,Zhou J,Zhao J,Jiang G,Zhang X,Zhang Y,Dong M

Sat Jun 01 00:00:00 EDT 2019

TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.

Molecular carcinogenesis

Zhang X,Han S,Zhou H,Cai L,Li J,Liu N,Liu Y,Wang L,Fan C,Li A,Miao Y

Wed May 01 00:00:00 EDT 2019

TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.

Molecular carcinogenesis

Zhang X,Han S,Zhou H,Cai L,Li J,Liu N,Liu Y,Wang L,Fan C,Li A,Miao Y

Wed May 01 00:00:00 EDT 2019

One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats.

Nutritional neuroscience

Rijnsburger M,Unmehopa UA,Eggels L,Serlie MJ,la Fleur SE

Thu Aug 01 00:00:00 EDT 2019

One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats.

Nutritional neuroscience

Rijnsburger M,Unmehopa UA,Eggels L,Serlie MJ,la Fleur SE

Thu Aug 01 00:00:00 EDT 2019

Red yeast rice ameliorates high-fat diet-induced atherosclerosis in Apoe^-/- mice in association with improved inflammation and altered gut microbiota composition.

Food & function

Dong Y,Cheng H,Liu Y,Xue M,Liang H

Wed Jul 17 00:00:00 EDT 2019

Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lan XB,Wang Q,Yang JM,Ma L,Zhang WJ,Zheng P,Sun T,Niu JG,Liu N,Yu JQ

Tue Oct 01 00:00:00 EDT 2019

Hypertensive Rats Treated Chronically With N^ω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.

Frontiers in pharmacology

Li B,He X,Lei SS,Zhou FC,Zhang NY,Chen YH,Wang YZ,Su J,Yu JJ,Li LZ,Zheng X,Luo R,Kołodyńska D,Xiong S,Lv GY,Chen SH

Mon Sep 28 00:00:00 EDT 2020

Semen hoveniae extract ameliorates alcohol-induced chronic liver damage in rats via modulation of the abnormalities of gut-liver axis.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Qiu P,Dong Y,Zhu T,Luo YY,Kang XJ,Pang MX,Li HZ,Xu H,Gu C,Pan SH,Du WF,Ge WH

Tue Jan 01 00:00:00 EST 2019

Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.

Scientific reports

Li Z,Yu Y,Wang M,Xu H,Han B,Jiang P,Ma H,Li Y,Tian C,Zhou D,Li X,Ye X

Wed Jan 16 00:00:00 EST 2019

Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.

Frontiers in microbiology

Bian X,Wu W,Yang L,Lv L,Wang Q,Li Y,Ye J,Fang D,Wu J,Jiang X,Shi D,Li L

Thu Oct 01 00:00:00 EDT 2020

Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.

Clinical science (London, England : 1979)

Chai S,Liu K,Feng W,Liu T,Wang Q,Zhou R,Chen S,Wang L,Chen G,Ming T,Zhao J,Liu C,Xue B

Thu Feb 14 00:00:00 EST 2019

Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.

Clinical science (London, England : 1979)

Chai S,Liu K,Feng W,Liu T,Wang Q,Zhou R,Chen S,Wang L,Chen G,Ming T,Zhao J,Liu C,Xue B

Thu Feb 14 00:00:00 EST 2019

Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.

Journal of applied toxicology : JAT

Adegoke EO,Adeniran SO,Zeng Y,Wang X,Wang H,Wang C,Zhang H,Zheng P,Zhang G

Sat Jun 01 00:00:00 EDT 2019

Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis.

Cell death & disease

Li H,Shen S,Ruan X,Liu X,Zheng J,Liu Y,Yang C,Wang D,Liu L,Ma J,Ma T,Wang P,Cai H,Li Z,Zhao L,Xue Y

Fri Dec 20 00:00:00 EST 2019

Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability.

Molecular therapy. Nucleic acids

Guo J,Shen S,Liu X,Ruan X,Zheng J,Liu Y,Liu L,Ma J,Ma T,Shao L,Wang D,Yang C,Xue Y

Fri Dec 06 00:00:00 EST 2019

The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.

Food & function

Zhang M,Zhao J,Deng J,Duan Z,Zhu C,Fan D

Wed Jul 17 00:00:00 EDT 2019

High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.

Mediators of inflammation

Su YR,Hong YP,Mei FC,Wang CY,Li M,Zhou Y,Zhao KL,Yu J,Wang WX

Mon Jul 06 00:00:00 EDT 2020

Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice.

International journal of biological macromolecules

Feng Y,Weng H,Ling L,Zeng T,Zhang Y,Chen D,Li H

Mon Jul 01 00:00:00 EDT 2019

Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Jiang YP,Yang JM,Ye RJ,Liu N,Zhang WJ,Ma L,Zheng P,Niu JG,Liu P,Yu JQ

Sun Dec 01 00:00:00 EST 2019

Ischemia-Reperfusion Injury of Sciatic Nerve in Rats: Protective Role of Combination of Vitamin C with E and Tissue Plasminogen Activator.

Neurochemical research

Apostolopoulou K,Konstantinou D,Alataki R,Papapostolou I,Zisimopoulos D,Kalaitzopoulou E,Bravou V,Lilis I,Angelatou F,Papadaki H,Georgiou CD,Chroni E

Thu Mar 01 00:00:00 EST 2018

Ischemia-Reperfusion Injury of Sciatic Nerve in Rats: Protective Role of Combination of Vitamin C with E and Tissue Plasminogen Activator.

Neurochemical research

Apostolopoulou K,Konstantinou D,Alataki R,Papapostolou I,Zisimopoulos D,Kalaitzopoulou E,Bravou V,Lilis I,Angelatou F,Papadaki H,Georgiou CD,Chroni E

Thu Mar 01 00:00:00 EST 2018

Rapid Communication: Porcine CRTC3 gene clone, expression pattern, and its regulatory role in intestinal epithelial cells.

Journal of animal science

Liu J,You W,Xu Z,Chen B,Wang Y,Shan T

Fri Jun 29 00:00:00 EDT 2018

Rapid Communication: Porcine CRTC3 gene clone, expression pattern, and its regulatory role in intestinal epithelial cells.

Journal of animal science

Liu J,You W,Xu Z,Chen B,Wang Y,Shan T

Fri Jun 29 00:00:00 EDT 2018

Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.

BioMed research international

Lu S,Zhang T,Gu W,Yang X,Lu J,Zhao R,Yu J

Tue Dec 11 00:00:00 EST 2018

Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.

BioMed research international

Lu S,Zhang T,Gu W,Yang X,Lu J,Zhao R,Yu J

Tue Dec 11 00:00:00 EST 2018

miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.

Cell death & disease

Liu L,Yao J,Li Z,Zu G,Feng D,Li Y,Qasim W,Zhang S,Li T,Zeng H,Tian X

Wed Mar 14 00:00:00 EDT 2018

miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.

Cell death & disease

Liu L,Yao J,Li Z,Zu G,Feng D,Li Y,Qasim W,Zhang S,Li T,Zeng H,Tian X

Wed Mar 14 00:00:00 EDT 2018

IL-8 antagonist, CXCL8(3-72)K11R/G31P coupled with probiotic exhibit variably enhanced therapeutic potential in ameliorating ulcerative colitis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Walana W,Ye Y,Li M,Wang J,Wang B,Cheng JW,Gordon JR,Li F

Sun Jul 01 00:00:00 EDT 2018

Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.

Molecular pharmaceutics

Wu W,Wang S,Liu Q,Shan T,Wang Y

Mon Aug 06 00:00:00 EDT 2018

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang X,Hu L,Li H

Thu May 31 00:00:00 EDT 2018

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang X,Hu L,Li H

Thu May 31 00:00:00 EDT 2018

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang X,Hu L,Li H

Thu May 31 00:00:00 EDT 2018

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang X,Hu L,Li H

Thu May 31 00:00:00 EDT 2018

2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Zhang Z,Zhang L,Chen J,Cao Y,Qu M,Lin X,Han Z,Ji X

Fri Jun 01 00:00:00 EDT 2018

PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.

Journal of pharmacological sciences

Xue TF,Ding X,Ji J,Yan H,Huang JY,Guo XD,Yang J,Sun XL

Wed Nov 01 00:00:00 EDT 2017

PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.

Journal of pharmacological sciences

Xue TF,Ding X,Ji J,Yan H,Huang JY,Guo XD,Yang J,Sun XL

Wed Nov 01 00:00:00 EDT 2017

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.

Oncotarget

Zhang X,Zhang Y,Miao Y,Zhou H,Jiang G,Wang E

Tue Sep 19 00:00:00 EDT 2017

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.

Oncotarget

Zhang X,Zhang Y,Miao Y,Zhou H,Jiang G,Wang E

Tue Sep 19 00:00:00 EDT 2017

PROTECTIVE EFFECTS OF ETHYL ACETATE EXTRACTION FROM GASTRODIA ELATA BLUME ON BLOOD-BRAIN BARRIER IN FOCAL CEREBRAL ISCHEMIA REPERFUSION.

African journal of traditional, complementary, and alternative medicines : AJTCAM

He F,Duan X,Dai R,Wang W,Yang C,Lin Q

Fri Sep 08 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: Occludin; phosphatase 1, regulatory subunit 115; tight junction protein occludin

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Gene Aliases: AI503564; BLCPMG; Ocl; OCLN; PPP1R115

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UniProt ID: (Human) Q16625, (Mouse) Q61146, (Rat) Q6P6T5

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Entrez Gene ID: (Human) 100506658, (Mouse) 18260, (Rat) 83497

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Function(s)

protein binding thiopurine S-methyltransferase activity protein domain specific binding S-adenosylmethionine-dependent methyltransferase activity structural molecule activity general transcription factor

Process(es)

protein complex assembly methylation cell-cell junction organization S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process bicellular tight junction assembly

Performance Guarantee

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Occludin Polyclonal Antibody

Occludin Antibody (27260-1-AP) in ICC/IF

Product Details

27260-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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