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Product Details
BS-15509R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Orexin A, amino acids 34-66.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hcrt; Hypocretin; Hypocretin (orexin) neuropeptide; Hypocretin neuropeptide precursor; orexin; orexin A; orexin B; Orexin precursor; Prepro-orexin; Preprohypocretin
Gene Aliases: HCRT; NRCLP1; orexin-A; OX; PPORX; PPOX
UniProt ID: (Human) O43612, (Mouse) O55241, (Rat) O55232
Entrez Gene ID: (Human) 3060, (Mouse) 15171, (Rat) 25723
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
negative regulation of DNA replication
eating behavior
negative regulation of potassium ion transport
regulation of neurotransmitter secretion
positive regulation of calcium ion transport
negative regulation of transmission of nerve impulse
positive regulation of transmission of nerve impulse
excitatory postsynaptic potential
temperature homeostasis
feeding behavior
behavioral fear response
release of sequestered calcium ion into cytosol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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