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Product Details
MA5-43930
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
J10
Immunogen
Ala21-Pro99 (Accession P02818), with N-terminal His Tag
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2912862
Target Information
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5
Gene Aliases: BGLAP; BGP; OC; OCN
UniProt ID: (Human) P02818
Entrez Gene ID: (Human) 632
skeletal system development
osteoblast differentiation
osteoblast development
signal peptide processing
ER to Golgi vesicle-mediated transport
cell adhesion
cell aging
response to mechanical stimulus
response to gravity
response to zinc ion
response to activity
peptidyl-glutamic acid carboxylation
bone mineralization
regulation of bone mineralization
response to vitamin K
response to vitamin D
response to testosterone
response to hydroxyisoflavone
odontogenesis
response to drug
response to estrogen
regulation of bone resorption
response to ethanol
regulation of osteoclast differentiation
response to glucocorticoid
bone development
cellular response to vitamin D
cellular response to growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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