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Product Details
50114-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Chicken,
Goat,
Human,
Sheep,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OC4-30
Immunogen
Bovine osteocalcin
Conjugate
Form
Lyophilized
Concentration
0.5-1.0 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 50 µL of distilled water (2 mg/mL final concentration) then dilute further for applications in PBS or media that is identical to that used in the assay system.
Target Information
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamate protein osteocalcin; bone gamma-carboxyglutamate; BGLAP; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); Bone Gla protein; bone gla protein BGP; bone Gla-protein; gamma-carbooxyglutamate (gla) protein; Gamma-carboxyglutamic acid-containing protein; Gla; Osteocalcin; PMF1; RP11-54H19.5
Gene Aliases: BGLAP; Bglap2; BGP; Bgpr; Bgpra; GLA; OC; OCN
UniProt ID: (Human) P02818, (Rat) P04640
Entrez Gene ID: (Dog) 403762, (Chicken) 396348, (Sheep) 677670, (Human) 632, (Rabbit) 100340503, (Pig) 397530, (Goat) 100861188, (Rat) 25295
regulation of bone mineralization
biomineral tissue development
response to vitamin K
regulation of cellular response to insulin stimulus
ossification
osteoblast differentiation
bone development
skeletal system development
osteoblast development
signal peptide processing
ER to Golgi vesicle-mediated transport
cell adhesion
cell aging
response to mechanical stimulus
response to gravity
response to zinc ion
response to activity
peptidyl-glutamic acid carboxylation
bone mineralization
response to vitamin D
response to testosterone
response to hydroxyisoflavone
odontogenesis
response to drug
response to estrogen
regulation of bone resorption
response to ethanol
regulation of osteoclast differentiation
response to glucocorticoid
cellular response to vitamin D
cellular response to growth factor stimulus
aging
response to inorganic substance
response to organic cyclic compound
response to nutrient levels
cellular response to BMP stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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