Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
50118-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OCG2
Immunogen
Bovine osteocalcin
Conjugate
Form
Lyophilized
Concentration
0.5-1.0 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 50 µL of distilled water (2 mg/mL final concentration) then dilute further for applications in PBS or media that is identical to that used in the assay system.
Target Information
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5; unnamed protein product
Gene Aliases: BGLAP; BGP; OC; OCN
UniProt ID: (Human) P02818, (Bovine) P02820
Entrez Gene ID: (Human) 632, (Bovine) 281646
skeletal system development
osteoblast differentiation
osteoblast development
signal peptide processing
ER to Golgi vesicle-mediated transport
cell adhesion
cell aging
response to mechanical stimulus
response to gravity
response to zinc ion
response to activity
peptidyl-glutamic acid carboxylation
bone mineralization
regulation of bone mineralization
response to vitamin K
response to vitamin D
response to testosterone
response to hydroxyisoflavone
odontogenesis
response to drug
response to estrogen
regulation of bone resorption
response to ethanol
regulation of osteoclast differentiation
response to glucocorticoid
bone development
cellular response to vitamin D
cellular response to growth factor stimulus
biomineral tissue development
regulation of cellular response to insulin stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support