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Product Details
PA5-112637
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Oxytocin-neurophysin 1 protein (27-123AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867372
Target Information
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurophysin 1; neurophysin I; OT-NPI; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; Oxytocin-neurophysin 1; oxytocin-neurophysin I, preproprotein
Gene Aliases: OT; OT-NPI; OXT; OXT-NPI; Oxy
UniProt ID: (Human) P01178, (Mouse) P35454
Entrez Gene ID: (Human) 5020, (Mouse) 18429
response to amphetamine
regulation of heart rate
maternal aggressive behavior
signal transduction
positive regulation of cytosolic calcium ion concentration
heart development
female pregnancy
memory
grooming behavior
response to sucrose
positive regulation of norepinephrine secretion
response to activity
sleep
response to food
positive regulation of prostaglandin secretion
response to estradiol
response to retinoic acid
response to progesterone
response to prostaglandin E
social behavior
negative regulation of urine volume
positive regulation of renal sodium excretion
response to cocaine
hyperosmotic salinity response
maternal behavior
sperm ejaculation
eating behavior
drinking behavior
response to peptide hormone
response to ether
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of ossification
positive regulation of female receptivity
positive regulation of synaptic transmission
response to glucocorticoid
response to cAMP
response to electrical stimulus
regulation of sensory perception of pain
positive regulation of synapse assembly
male mating behavior
positive regulation of penile erection
positive regulation of hindgut contraction
negative regulation of gastric acid secretion
positive regulation of uterine smooth muscle contraction
response to organic cyclic compound
regulation of digestive system process
Performance Guarantee
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