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This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
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Protein Aliases: channel-interacting PDZ domain protein; Channel-interacting PDZ domain-containing protein; inactivation no after-potential D-like protein; inactivation-no-afterpotential D-like; InaD-like 2; InaD-like protein; Inadl protein; novel ankyrin-repeat protein; PALS1-associated tight junction protein; PDZ domain protein; Protein associated to tight junctions
Gene Aliases: Cipp; hINADL; InaD-like; INADL; Inadl2; Patj; RGD1565362
UniProt ID: (Mouse) Q63ZW7, (Rat) F1MAD2
Entrez Gene ID: (Mouse) 12695, (Rat) 140581, (Human) 10207
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