Proteintech

PAX6 Polyclonal Antibody

PAX6 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 12

PAX6 Antibody (12323-1-AP) in ICC/IF

Immunofluorescent staining of PAX6 (12323-1-AP, 1:250 dilution) with 4% PFA fixed control human induced pluripotent stem cells (hiPSC) derived neuronal precursor cells (NPCs). (Green: PAX6; Blue: DAPI). Provided by BioTalentum Ltd., Hungary.

PAX6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PAX6 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

12323-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 12 publications 12 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 35 publications 35 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PAX6 Fusion Protein Ag2984 (1-330 aa encoded by BC011953)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MQNSHSGVN QLGGVFVNGR PLPDSTRQKI VELAHSGARP CDISRILQVS NGCVSKILGR YYETGSIRPR AIGGSKPRVA TPEVVSKIAQ YKRECPSIFA WEIRDRLLSE GVCTNDNIPS VSSINRVLRN LASEKQQMGA DGMYDKLRML NGQTGSWGTR PGWYPGTSVP GQPTQDGCQQ QEGGGENTNS ISSNGEDSDE AQMRLQLKRK LQRNRTSFTQ EQIEALEKEF ERTHYPDVFA RERLAAKIDL PEARIQVWFS NRRAKWRREE KLRNQRRQAS NTPSHIPISS SFSTSVYQPI PQPTTPVSSF TSGSMLGRTD TALTNTYSAL P (1-330 aa encoded by BC011953)

Target Information

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transient neurogenesis in ischemic cortex from Sox2⁺ astrocytes.

Neural regeneration research

Yang JL,Fan H,Fu FF,Guo BL,Huang Y,Sun L,Wang WT,Xing JL,Hu XT,Ding YQ,Zhang K,Hu YZ,Wang YZ

Sat Jul 01 00:00:00 EDT 2023

Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi002-A) from a patient with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.

Stem cell research

Zhang C,Wang D,Wang Y,Sun P,Zhao D,Zhao X,Zhao Y,Liu F,Xu J,Yan C

Thu Jun 01 00:00:00 EDT 2023

Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.

CNS neuroscience & therapeutics

Shen K,Wu D,Sun B,Zhu Y,Wang H,Zou W,Ma Y,Lu Z

Sun Jan 01 00:00:00 EST 2023

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons.

Cell reports

Sharma SD,Reddy BK,Pal R,Ritakari TE,Cooper JD,Selvaraj BT,Kind PC,Chandran S,Wyllie DJA,Chattarji S

Tue Apr 25 00:00:00 EDT 2023

iASPP regulates neurite development by interacting with Spectrin proteins.

Frontiers in molecular neuroscience

Wang J,Jia C,Gao Q,Zhang J,Gu X

Thu Jun 08 00:00:00 EDT 2023

NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice.

eLife

Zhang R,Mao W,Niu L,Bao W,Wang Y,Wang Y,Zhu Y,Yang Z,Chen J,Dong J,Cai M,Yuan Z,Song H,Li G,Zhang M,Xiong N,Wei J,Dong Z

Thu Apr 27 00:00:00 EDT 2023

Quantitation of Pax-6 protein in ocular impression cytology samples using an electrochemiluminescence immunoassay.

Analytical biochemistry

Zaworski PG,Schwartz R,Burr J,Skutnik D,Mollin A,Kumar B,Ngumah Q,Welch E,Johnson B,Narasimhan J,Weetall M

Tue Nov 01 00:00:00 EDT 2022

Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.

Cell discovery

Dou S,Wang Q,Zhang B,Wei C,Wang H,Liu T,Duan H,Jiang H,Liu M,Qi X,Zhou Q,Xie L,Shi W,Gao H

Tue Jul 12 00:00:00 EDT 2022

In-vitro differentiation of human embryonic stem cells into spinal cord neural stem cells.

Neuroreport

Chen X,Zhao T,Ke N,Qian Y,Wang W,Liu L,Liu C

Tue Aug 02 00:00:00 EDT 2022

In-vitro differentiation of human embryonic stem cells into spinal cord neural stem cells.

Neuroreport

Chen X,Zhao T,Ke N,Qian Y,Wang W,Liu L,Liu C

Tue Aug 02 00:00:00 EDT 2022

Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi001-A) from a healthy female Chinese Han.

Stem cell research

Wang D,Zhang R,Wang Y,Sun P,Ji X,Sun X,Xu J,Zhao D,Yan C,Liu F

Fri Jul 01 00:00:00 EDT 2022

ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.

Frontiers in oncology

Wen X,Chen S,Chen X,Qiu H,Wang W,Zhang N,Liu W,Wang T,Ding X,Zhang L

Wed Oct 19 00:00:00 EDT 2022

Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.

Human molecular genetics

Jin Y,Gao X,Lu M,Chen G,Yang X,Ren N,Song Y,Hou C,Li J,Liu Q,Gao J

Mon Oct 10 00:00:00 EDT 2022

Binge-like Prenatal Ethanol Exposure Causes Impaired Cellular Differentiation in the Embryonic Forebrain and Synaptic and Behavioral Defects in Adult Mice.

Brain sciences

Subbanna S,Basavarajappa BS

Fri Jun 17 00:00:00 EDT 2022

Generation of a human induced pluripotent stem cell line (INNDSUi003-A) derived from patient with Becker muscular dystrophy (BMD).

Stem cell research

Ji X,Wang Y,Sun P,Wang D,Sun X,Zhang R,Xu J,Li W,Liu F,Yan C

Fri Jul 01 00:00:00 EDT 2022

miR-124- and let-7-Mediated Reprogram of Human Fibroblasts into SST Interneurons.

ACS chemical neuroscience

Gu X,Wang J,Jiang X

Wed Sep 21 00:00:00 EDT 2022

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.

Cell stem cell

Yang M,Yu H,Yu X,Liang S,Hu Y,Luo Y,Izsvák Z,Sun C,Wang J

Thu Mar 03 00:00:00 EST 2022

Nicotinamide improves in vitro lens regeneration in a mouse capsular bag model.

Stem cell research & therapy

Liu X,Zhou Q,Huang Y,Fan Z,Duan H,Wang M,Li Z,Xie L

Thu May 12 00:00:00 EDT 2022

CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

Nature communications

de Thonel A,Ahlskog JK,Daupin K,Dubreuil V,Berthelet J,Chaput C,Pires G,Leonetti C,Abane R,Barris LC,Leray I,Aalto AL,Naceri S,Cordonnier M,Benasolo C,Sanial M,Duchateau A,Vihervaara A,Puustinen MC,Miozzo F,Fergelot P,Lebigot É,Verloes A,Gressens P,Lacombe D,Gobbo J,Garrido C,Westerheide SD,David L,Petitjean M,Taboureau O,Rodrigues-Lima F,Passemard S,Sabéran-Djoneidi D,Nguyen L,Lancaster M,Sistonen L,Mezger V

Wed Nov 16 00:00:00 EST 2022

Immunohistochemical evidence for adult human neurogenesis in health and disease.

WIREs mechanisms of disease

Gault N,Szele FG

Mon Nov 01 00:00:00 EDT 2021

Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.

Molecular and cellular endocrinology

Guo X,Cui C,Song J,He Q,Zang N,Hu H,Wang X,Li D,Wang C,Hou X,Li X,Liang K,Yan F,Chen L

Mon Nov 01 00:00:00 EDT 2021

Human neuropathology confirms projection neuron and interneuron defects and delayed oligodendrocyte production and maturation in FOXG1 syndrome.

European journal of medical genetics

Wilpert NM,Marguet F,Maillard C,Guimiot F,Martinovic J,Drunat S,Attié-Bitach T,Razavi F,Tessier A,Capri Y,Laquerrière A,Bahi-Buisson N

Wed Sep 01 00:00:00 EDT 2021

Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea.

Investigative ophthalmology & visual science

Díaz NM,Lang RA,Van Gelder RN,Buhr ED

Wed Jun 03 00:00:00 EDT 2020

Zinc Promotes Patient-Derived Induced Pluripotent Stem Cell Neural Differentiation via ERK-STAT Signaling.

Stem cells and development

Yang M,Bao D,Shi A,Yuan H,Wang J,He W,Tong X,Qin H

Wed Jul 01 00:00:00 EDT 2020

Computational and functional analyses of T2D GWAS SNPs for transcription factor binding.

Biochemical and biophysical research communications

Cheng M,Huang X,Zhang M,Huang Q

Thu Mar 12 00:00:00 EDT 2020

PAX6 contributes to the activation and proliferation of hepatic stellate cells via activating Hedgehog/GLI1 pathway.

Biochemical and biophysical research communications

Li C,Tan YH,Sun J,Deng FM,Liu YL

Thu May 28 00:00:00 EDT 2020

Perinatal exposure to nonylphenol promotes proliferation of granule cell precursors in offspring cerebellum: Involvement of the activation of Notch2 signaling.

Neurochemistry international

Fang Y,Che X,You M,Xu Y,Wang Y

Sun Nov 01 00:00:00 EDT 2020

Δ⁹-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons.

Molecular and cellular neurosciences

Shum C,Dutan L,Annuario E,Warre-Cornish K,Taylor SE,Taylor RD,Andreae LC,Buckley NJ,Price J,Bhattacharyya S,Srivastava DP

Sun Mar 01 00:00:00 EST 2020

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.

Nature communications

Sun X,Peng X,Cao Y,Zhou Y,Sun Y

Fri Jun 12 00:00:00 EDT 2020

The generation of an induced pluripotent stem cell line (DCGi001-A) from an individual with FOXG1 syndrome carrying the c.460dupG (p.Glu154fs) variation in the FOXG1 gene.

Stem cell research

Waite AJ,Millar D,Clarke A

Tue Dec 01 00:00:00 EST 2020

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Cell metabolism

Zhong X,Cui P,Cai Y,Wang L,He X,Long P,Lu K,Yan R,Zhang Y,Pan X,Zhao X,Li W,Zhang H,Zhou Q,Gao P

Tue Apr 02 00:00:00 EDT 2019

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Cell metabolism

Zhong X,Cui P,Cai Y,Wang L,He X,Long P,Lu K,Yan R,Zhang Y,Pan X,Zhao X,Li W,Zhang H,Zhou Q,Gao P

Tue Apr 02 00:00:00 EDT 2019

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Cell stem cell

Huang M,Tailor J,Zhen Q,Gillmor AH,Miller ML,Weishaupt H,Chen J,Zheng T,Nash EK,McHenry LK,An Z,Ye F,Takashima Y,Clarke J,Ayetey H,Cavalli FMG,Luu B,Moriarity BS,Ilkhanizadeh S,Chavez L,Yu C,Kurian KM,Magnaldo T,Sevenet N,Koch P,Pollard SM,Dirks P,Snyder MP,Largaespada DA,Cho YJ,Phillips JJ,Swartling FJ,Morrissy AS,Kool M,Pfister SM,Taylor MD,Smith A,Weiss WA

Thu Sep 05 00:00:00 EDT 2019

LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration.

Molecular brain

Mao R,Deng R,Wei Y,Han L,Meng Y,Xie W,Jia Z

Thu Jul 18 00:00:00 EDT 2019

Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation.

ACS nano

Zhang J,Chen Y,Gao M,Wang Z,Liu R,Xia T,Liu S

Tue Feb 26 00:00:00 EST 2019

Rapid Differentiation of Multi-Zone Ocular Cells from Human Induced Pluripotent Stem Cells and Generation of Corneal Epithelial and Endothelial Cells.

Stem cells and development

Li Z,Duan H,Li W,Hu X,Jia Y,Zhao C,Zhang S,Zhou Q,Shi W

Mon Apr 01 00:00:00 EDT 2019

Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yang SC,Liu JJ,Wang CK,Lin YT,Tsai SY,Chen WJ,Huang WK,Tu PA,Lin YC,Chang CF,Cheng CL,Lin H,Lai CY,Lin CY,Lee YH,Chiu YC,Hsu CC,Hsu SC,Hsiao M,Schuyler SC,Lu FL,Lu J

Sun Sep 01 00:00:00 EDT 2019

The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.

Cell death & disease

Wu DM,Zhang T,Liu YB,Deng SH,Han R,Liu T,Li J,Xu Y

Thu Apr 25 00:00:00 EDT 2019

The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.

Cell death & disease

Wu DM,Zhang T,Liu YB,Deng SH,Han R,Liu T,Li J,Xu Y

Thu Apr 25 00:00:00 EDT 2019

The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.

Cell death & disease

Wu DM,Zhang T,Liu YB,Deng SH,Han R,Liu T,Li J,Xu Y

Thu Apr 25 00:00:00 EDT 2019

Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex.

Cell reports

Arai Y,Cwetsch AW,Coppola E,Cipriani S,Nishihara H,Kanki H,Saillour Y,Freret-Hodara B,Dutriaux A,Okada N,Okano H,Dehay C,Nardelli J,Gressens P,Shimogori T,D'Onofrio G,Pierani A

Tue Oct 15 00:00:00 EDT 2019

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults.

Cerebral cortex (New York, N.Y. : 1991)

Cipriani S,Ferrer I,Aronica E,Kovacs GG,Verney C,Nardelli J,Khung S,Delezoide AL,Milenkovic I,Rasika S,Manivet P,Benifla JL,Deriot N,Gressens P,Adle-Biassette H

Sun Jul 01 00:00:00 EDT 2018

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults.

Cerebral cortex (New York, N.Y. : 1991)

Cipriani S,Ferrer I,Aronica E,Kovacs GG,Verney C,Nardelli J,Khung S,Delezoide AL,Milenkovic I,Rasika S,Manivet P,Benifla JL,Deriot N,Gressens P,Adle-Biassette H

Sun Jul 01 00:00:00 EDT 2018

miR-342-5p Regulates Neural Stem Cell Proliferation and Differentiation Downstream to Notch Signaling in Mice.

Stem cell reports

Gao F,Zhang YF,Zhang ZP,Fu LA,Cao XL,Zhang YZ,Guo CJ,Yan XC,Yang QC,Hu YY,Zhao XH,Wang YZ,Wu SX,Ju G,Zheng MH,Han H

Tue Apr 11 00:00:00 EDT 2017

miR-342-5p Regulates Neural Stem Cell Proliferation and Differentiation Downstream to Notch Signaling in Mice.

Stem cell reports

Gao F,Zhang YF,Zhang ZP,Fu LA,Cao XL,Zhang YZ,Guo CJ,Yan XC,Yang QC,Hu YY,Zhao XH,Wang YZ,Wu SX,Ju G,Zheng MH,Han H

Tue Apr 11 00:00:00 EDT 2017

Dynamic Expression Patterns of Progenitor and Neuron Layer Markers in the Developing Human Dentate Gyrus and Fimbria.

Cerebral cortex (New York, N.Y. : 1991)

Cipriani S,Journiac N,Nardelli J,Verney C,Delezoide AL,Guimiot F,Gressens P,Adle-Biassette H

Sun Jan 01 00:00:00 EST 2017

Hydrocephalus due to multiple ependymal malformations is caused by mutations in the MPDZ gene.

Acta neuropathologica communications

Saugier-Veber P,Marguet F,Lecoquierre F,Adle-Biassette H,Guimiot F,Cipriani S,Patrier S,Brasseur-Daudruy M,Goldenberg A,Layet V,Capri Y,Gérard M,Frébourg T,Laquerrière A

Mon May 01 00:00:00 EDT 2017

Hydrocephalus due to multiple ependymal malformations is caused by mutations in the MPDZ gene.

Acta neuropathologica communications

Saugier-Veber P,Marguet F,Lecoquierre F,Adle-Biassette H,Guimiot F,Cipriani S,Patrier S,Brasseur-Daudruy M,Goldenberg A,Layet V,Capri Y,Gérard M,Frébourg T,Laquerrière A

Mon May 01 00:00:00 EDT 2017

Dynamic Expression Patterns of Progenitor and Pyramidal Neuron Layer Markers in the Developing Human Hippocampus.

Cerebral cortex (New York, N.Y. : 1991)

Cipriani S,Nardelli J,Verney C,Delezoide AL,Guimiot F,Gressens P,Adle-Biassette H

Tue Mar 01 00:00:00 EST 2016

Dynamic Expression Patterns of Progenitor and Pyramidal Neuron Layer Markers in the Developing Human Hippocampus.

Cerebral cortex (New York, N.Y. : 1991)

Cipriani S,Nardelli J,Verney C,Delezoide AL,Guimiot F,Gressens P,Adle-Biassette H

Tue Mar 01 00:00:00 EST 2016

Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.

Scientific reports

Ju J,Liu Q,Zhang Y,Liu Y,Jiang M,Zhang L,He X,Peng C,Zheng T,Lu QR,Li H

Fri Jul 29 00:00:00 EDT 2016

Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.

Scientific reports

Ju J,Liu Q,Zhang Y,Liu Y,Jiang M,Zhang L,He X,Peng C,Zheng T,Lu QR,Li H

Fri Jul 29 00:00:00 EDT 2016

MicroRNA-mediated non-cell-autonomous regulation of cortical radial glial transformation revealed by a Dicer1 knockout mouse model.

Glia

Zhang C,Ge X,Liu Q,Jiang M,Li MW,Li H

Fri May 01 00:00:00 EDT 2015

MicroRNA-mediated non-cell-autonomous regulation of cortical radial glial transformation revealed by a Dicer1 knockout mouse model.

Glia

Zhang C,Ge X,Liu Q,Jiang M,Li MW,Li H

Fri May 01 00:00:00 EDT 2015

PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.

Molecular brain

Pan X,Chang X,Leung C,Zhou Z,Cao F,Xie W,Jia Z

Fri Jun 05 00:00:00 EDT 2015

PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.

Molecular brain

Pan X,Chang X,Leung C,Zhou Z,Cao F,Xie W,Jia Z

Fri Jun 05 00:00:00 EDT 2015

Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.

Developmental biology

Hou C,Ding L,Zhang J,Jin Y,Sun C,Li Z,Sun X,Zhang T,Zhang A,Li H,Gao J

Sat Nov 01 00:00:00 EDT 2014

Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.

Developmental biology

Hou C,Ding L,Zhang J,Jin Y,Sun C,Li Z,Sun X,Zhang T,Zhang A,Li H,Gao J

Sat Nov 01 00:00:00 EDT 2014

A robust method to derive functional neural crest cells from human pluripotent stem cells.

American journal of stem cells

Kreitzer FR,Salomonis N,Sheehan A,Huang M,Park JS,Spindler MJ,Lizarraga P,Weiss WA,So PL,Conklin BR

Wed Jul 17 00:00:00 EDT 2013

A robust method to derive functional neural crest cells from human pluripotent stem cells.

American journal of stem cells

Kreitzer FR,Salomonis N,Sheehan A,Huang M,Park JS,Spindler MJ,Lizarraga P,Weiss WA,So PL,Conklin BR

Wed Jul 17 00:00:00 EDT 2013

Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a.

Molecular biology of the cell

Zhao X,Wu J,Zheng M,Gao F,Ju G

Wed Aug 01 00:00:00 EDT 2012

Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a.

Molecular biology of the cell

Zhao X,Wu J,Zheng M,Gao F,Ju G

Wed Aug 01 00:00:00 EDT 2012

Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a.

Molecular biology of the cell

Zhao X,Wu J,Zheng M,Gao F,Ju G

Wed Aug 01 00:00:00 EDT 2012

Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a.

Molecular biology of the cell

Zhao X,Wu J,Zheng M,Gao F,Ju G

Wed Aug 01 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: Aniridia; Aniridia type II protein; Dickie's small eye; Keratitis; MGC17209; Oculorhombin; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; Paired box protein Pax-6; small eye

View more View less

Gene Aliases: 1500038E17Rik; AEY11; AN; AN2; D11S812E; Dey; FVH1; Gsfaey11; MGDA; Pax-6; PAX6; Sey; WAGR

View more View less

UniProt ID: (Human) P26367, (Rat) P63016, (Mouse) P63015

View more View less

Entrez Gene ID: (Human) 5080, (Rat) 25509, (Mouse) 18508

View more View less

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity protein binding transcription factor binding protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding co-SMAD binding R-SMAD binding HMG box domain binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding AT DNA binding double-stranded DNA binding sequence-specific DNA binding transcription regulatory region DNA binding

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

PAX6 Polyclonal Antibody

PAX6 Antibody (12323-1-AP) in ICC/IF

Product Details

12323-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!