Product References
De novo genes with an lncRNA origin encode unique human brain developmental functionality.
Nature ecology & evolution
An NA,Zhang J,Mo F,Luan X,Tian L,Shen QS,Li X,Li C,Zhou F,Zhang B,Ji M,Qi J,Zhou WZ,Ding W,Chen JY,Yu J,Zhang L,Shu S,Hu B,Li CY
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to identifiy distinctive U1 elements and RNA splice-related sequences accounting for RNA nuclear export, differentiating mRNAs from lncRNAs, and driving the origin of de novo genes from lncRNA loci.
Wed Feb 01 00:00:00 EST 2023
De novo genes with an lncRNA origin encode unique human brain developmental functionality.
Nature ecology & evolution
An NA,Zhang J,Mo F,Luan X,Tian L,Shen QS,Li X,Li C,Zhou F,Zhang B,Ji M,Qi J,Zhou WZ,Ding W,Chen JY,Yu J,Zhang L,Shu S,Hu B,Li CY
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to identifiy distinctive U1 elements and RNA splice-related sequences accounting for RNA nuclear export, differentiating mRNAs from lncRNAs, and driving the origin of de novo genes from lncRNA loci.
Wed Feb 01 00:00:00 EST 2023
Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants.
Stem cell research
Jimenez-Tellez N,Vera CD,Yildirim Z,Vicente Guevara J,Zhang T,Wu JC
42-6600 was used in Immunocytochemistry-immunofluorescence to generate two human-induced pluripotent stem cell (iPSC) lines from two LQT patients carrying a missense mutation in SNTA1 (c.1088A > C).
Wed Feb 01 00:00:00 EST 2023
Generation of two human iPSC lines with Exon 3 mutations in BCL2-Associated Athanogene 3 (BAG3) from dilated cardiomyopathy patients.
Stem cell research
Zushin PH,Zhou Y,Li A,Ashley EA,Wheeler MT,Wu JC
42-6600 was used in Immunohistochemistry to generate two human iPSC lines from individuals with mutations in exon 3 of BAG3 and provide validation of their pluripotency and ability to differentiate toward the three primary germ layers.
Wed Mar 01 00:00:00 EST 2023
Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain.
The Journal of biological chemistry
Lin CH,Sun Y,Chan CSY,Wu MR,Gu L,Davis AE,Gu B,Zhang W,Tanasa B,Zhong LR,Emerson MM,Chen L,Ding JB,Wang S
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunohistochemistry (PFA fixed)
Fri Apr 01 00:00:00 EDT 2022
Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain.
The Journal of biological chemistry
Lin CH,Sun Y,Chan CSY,Wu MR,Gu L,Davis AE,Gu B,Zhang W,Tanasa B,Zhong LR,Emerson MM,Chen L,Ding JB,Wang S
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunohistochemistry (PFA fixed)
Fri Apr 01 00:00:00 EDT 2022
Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation.
Cells
Gajewska KA,Haynes JM,Jans DA
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunocytochemistry
Sun Jun 12 00:00:00 EDT 2022
Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients.
Stem cell research
Caudal A,Mondejar-Parreño G,Vera CD,Williams DR,Shenoy SP,Liang D,Wu JC
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to show that these patient-specific iPSC lines serve as valuable in vitro models for DCM pathology caused by PLN mutations.
Mon Aug 01 00:00:00 EDT 2022
Multiplexed genome regulation in vivo with hyper-efficient Cas12a.
Nature cell biology
Guo LY,Bian J,Davis AE,Liu P,Kempton HR,Zhang X,Chemparathy A,Gu B,Lin X,Rane DA,Xu X,Jamiolkowski RM,Hu Y,Wang S,Qi LS
42-6600 was used in In vivo experiments to offer a versatile in vivo tool for a broad range of gene-modulation and gene-therapy applications.
Fri Apr 01 00:00:00 EDT 2022
Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases.
Scientific reports
Brás J,Henriques D,Moreira R,Santana MM,Silva-Pedrosa R,Adão D,Braz S,Álvaro AR,de Almeida LP,Mendonça LS
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to indicate that the established organoids recapitulate important characteristics of human brain development and exhibit cerebellar features, constituting a resourceful tool for testing therapeutic approaches for cerebellar diseases.
Fri Jul 22 00:00:00 EDT 2022
Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene.
Stem cell research
Yildirim Z,Kojic A,Yan CD,Wu MA,Vagelos R,Wu JC
42-6600 was used in Immunocytochemistry-immunofluorescence to generate two human induced pluripotent stem cell (iPSC) lines generated from two DCM patients carrying variants in the HCN4 gene (c.2587G > T and c.2846G > A).
Thu Dec 01 00:00:00 EST 2022
The Metabolite Saccharopine Impairs Neuronal Development by Inhibiting the Neurotrophic Function of Glucose-6-Phosphate Isomerase.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Guo Y,Wu J,Wang M,Wang X,Jian Y,Yang C,Guo W
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to demonstrate saccharopine degradation is essential for neuronal development.
Wed Mar 30 00:00:00 EDT 2022
Generation of two induced pluripotent stem cell lines carrying the phospholamban R14del mutation for modeling ARVD/C.
Stem cell research
Vera CD,Manhas A,Shenoy SP,Wheeler MT,Sallam K,Wu JC
42-6600 was used in Immunocytochemistry-immunofluorescence to show two lines carrying this mutation with typical iPSC morphology, pluripotency, karyotype, ability to differentiate into the three germ layers in vitro, and readily availability for studying pathological mechanisms or ARVD/C. Copyright © 2022.
Mon Aug 01 00:00:00 EDT 2022
Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS).
Stem cell research
Alonzo M,Contreras J,Ye S,Lin H,Hernandez-Rosario L,McBride KL,Texter K,Garg V,Zhao MT
42-6600 was used in Immunocytochemistry and Flow Cytometry to generante and validate an iPSC line from the peripheral blood mononuclear cells of a male patient with hypoplastic left heart syndrome (HLHS) through Sendai virus-mediated transfection of 4 Yamanaka factors.
Sat Oct 01 00:00:00 EDT 2022
Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS).
Stem cell research
Alonzo M,Contreras J,Ye S,Lin H,Hernandez-Rosario L,McBride KL,Texter K,Garg V,Zhao MT
42-6600 was used in Immunocytochemistry and Flow Cytometry to generante and validate an iPSC line from the peripheral blood mononuclear cells of a male patient with hypoplastic left heart syndrome (HLHS) through Sendai virus-mediated transfection of 4 Yamanaka factors.
Sat Oct 01 00:00:00 EDT 2022
Compartmentalized microfluidic device for in vitro co-culture of retinal cells.
Biotechnology journal
Jahagirdar D,Yadav S,Gore M,Korpale V,Mathpati CS,Chidambaram S,Majumder A,Jain R,Dandekar P
42-6600 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to prove the functionality of the retinal coculture, which may be used as an appropriate perfusion-based, preclinical tool for the evaluation of novel retinal drugs and delivery systems.
Thu Sep 01 00:00:00 EDT 2022
Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants.
Stem cell research
Manhas A,Jahng JWS,Vera CD,Shenoy SP,Knowles JW,Wu JC
42-6600 was used in Immunocytochemistry-immunofluorescence to show that both iPSC lines expressed pluripotent markers, had a normal karyotype, and were able to differentiate into three germ layers, making them potentially valuable tools for modeling HCM in vitro and investigating the pathological mechanisms related to these two variants.
Sun May 01 00:00:00 EDT 2022
Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease.
Frontiers in cell and developmental biology
Cai M,Chai S,Xiong T,Wei J,Mao W,Zhu Y,Li X,Wei W,Dai X,Yang B,Liu W,Shu B,Wang M,Lu T,Cai Y,Zheng Z,Mei Z,Zhou Y,Yang J,Zhao J,Shen L,Ho JWK,Chen J,Xiong N
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunocytochemistry
Fri Sep 10 00:00:00 EDT 2021
Maternal Immune Activation Alters Fetal Brain Development and Enhances Proliferation of Neural Precursor Cells in Rats.
Frontiers in immunology
Baines KJ,Hillier DM,Haddad FL,Rajakumar N,Schmid S,Renaud SJ
42-6600 was used in Immunohistochemistry-immunofluorescence to suggest that MIA elicits rapid gene expression changes within the conceptus, including repression of neurodevelopmental pathways, resulting in profound alterations in fetal brain development.
Fri Apr 02 00:00:00 EDT 2021
Maternal Immune Activation Alters Fetal Brain Development and Enhances Proliferation of Neural Precursor Cells in Rats.
Frontiers in immunology
Baines KJ,Hillier DM,Haddad FL,Rajakumar N,Schmid S,Renaud SJ
42-6600 was used in Immunohistochemistry-immunofluorescence to suggest that MIA elicits rapid gene expression changes within the conceptus, including repression of neurodevelopmental pathways, resulting in profound alterations in fetal brain development.
Fri Apr 02 00:00:00 EDT 2021
Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution.
The EMBO journal
Yu XX,Qiu WL,Yang L,Zhang Y,He MY,Li LC,Xu CR
42-6600 was used in Immunohistochemistry-immunofluorescence to define multistep cell fate decision pathways during pancreatic development at single-cell resolution.
Mon Apr 15 00:00:00 EDT 2019
Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms.
BMC developmental biology
Goto-Silva L,Ayad NME,Herzog IL,Silva NP,Lamien B,Orlande HRB,da Costa Souza A,Ribeiro S,Martins M,Domont GB,Junqueira M,Tovar-Moll F,Rehen SK
42-6600 was used in Immunofluorescence in immunohistochemistry on frozen tissues to analyse the physical forces playing a role in brain organoid cultures in two different multiplex platforms.
Thu Mar 07 00:00:00 EST 2019
MicroRNA-365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6.
Glia
Mo JL,Liu Q,Kou ZW,Wu KW,Yang P,Chen XH,Sun FY
Sun Jul 01 00:00:00 EDT 2018
MicroRNA-365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6.
Glia
Mo JL,Liu Q,Kou ZW,Wu KW,Yang P,Chen XH,Sun FY
Sun Jul 01 00:00:00 EDT 2018
MicroRNA-365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6.
Glia
Mo JL,Liu Q,Kou ZW,Wu KW,Yang P,Chen XH,Sun FY
Sun Jul 01 00:00:00 EDT 2018
Comparison of in vitro Neuronal Differentiation Capacity Between Mouse Epiblast Stem Cells Derived From Nuclear Transfer and Naturally Fertilized Embryos.
Frontiers in molecular neuroscience
Li T,Zheng Y,Li Y,Ye D
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunofluorescence
Wed Sep 30 00:00:00 EDT 2020
In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells.
Stem cell reports
Steens J,Zuk M,Benchellal M,Bornemann L,Teichweyde N,Hess J,Unger K,Görgens A,Klump H,Klein D
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunohistochemistry
Tue Apr 11 00:00:00 EDT 2017
Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.
eLife
Bassett EA,Tokarew N,Allemano EA,Mazerolle C,Morin K,Mears AJ,McNeill B,Ringuette R,Campbell C,Smiley S,Pokrajac NT,Dubuc AM,Ramaswamy V,Northcott PA,Remke M,Monnier PP,Potter D,Paes K,Kirkpatrick LL,Coker KJ,Rice DS,Perez-Iratxeta C,Taylor MD,Wallace VA
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Immunofluorescence
Tue Nov 08 00:00:00 EST 2016
Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs.
Stem cell reports
Fang D,Qing Y,Yan S,Chen D,Yan SS
Published figure using PAX6 polyclonal antibody (Product # 42-6600) in Western Blot
Tue Oct 11 00:00:00 EDT 2016
Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons.
Scientific reports
Fang D,Yan S,Yu Q,Chen D,Yan SS
42-6600 was used in immunocytochemistry and western blot study mitochondrial development, neurogenesis, and synapse formation in human induced pluripotent stem cell-derived cortical neurons
Thu Aug 18 00:00:00 EDT 2016
De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells.
The Journal of biological chemistry
Wang J,Wang Y,Lu L
42-6600 was used in western blot to report that regulation of CTCF by de-SUMOylation is dependent upon hypoxic and oxidative stresses.
Fri Apr 06 00:00:00 EDT 2012
De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells.
The Journal of biological chemistry
Wang J,Wang Y,Lu L
42-6600 was used in western blot to report that regulation of CTCF by de-SUMOylation is dependent upon hypoxic and oxidative stresses.
Fri Apr 06 00:00:00 EDT 2012
De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells.
The Journal of biological chemistry
Wang J,Wang Y,Lu L
42-6600 was used in western blot to report that regulation of CTCF by de-SUMOylation is dependent upon hypoxic and oxidative stresses.
Fri Apr 06 00:00:00 EDT 2012