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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PVSVHTRPPM KEVVRSCTPM KESTTMEIWI HPQPQRKSEG KVAGKSQRRV TF
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PCDH-X; protein phosphatase 1, regulatory subunit 119; protocadherin 11X; Protocadherin on the X chromosome; Protocadherin-11; Protocadherin-11 X-linked; Protocadherin-S
Gene Aliases: KIAA1326; PCDH-X; PCDH11; PCDH11X; PCDHX; PPP1R119
UniProt ID: (Human) Q9BZA7
Entrez Gene ID: (Human) 27328
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