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Immunogen sequence: GGLHVDLAQI IEACDVCLKE DDKDVESVMN SVVSLLLILE PDKQEALIES LCEKLVKFRE GERPSLRLQL LSNLFHGMDK NTPVRYTVYC SLIKVAASCG AIQYIPTELD QVRKWISDWN LTTEKKHTLL RLLYEALVDC KKS
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B5 receptor; dendritic cell protein; EIF3M; Eukaryotic translation initiation factor 3 subunit M; eukaryotic translation initiation factor 3, subunit M; Fetal lung protein B5; FLJ29030; hFL-B5; PCI domain containing 1 (herpesvirus entry mediator); PCI domain-containing protein 1; transport and golgi organization 7 homolog
Gene Aliases: B5; EIF3M; GA17; hfl-B5; HFLB5; PCID1; PNAS-125; TANGO7
UniProt ID: (Human) Q7L2H7
Entrez Gene ID: (Human) 10480
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