Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: SHGIFPDPSK DMQVPTIEKS HSSPGSSKSS SEGHLRSHGP SRSQSKTSVT
Sequence homology: Cow: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Aczonin; PCLO; Protein piccolo
Gene Aliases: ACZ; KIAA0559; PCH3; PCLO
UniProt ID: (Human) Q9Y6V0
Entrez Gene ID: (Human) 27445
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