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Immunogen sequence: PPASADETF THHLQRLRKL IKKRSELYEA EERALRVMLE GEQEEERKRE LEKKQRKEKE KILLQKREIE SKLFGDPDEF PLAHLLEPFR QYYLQAEHSL PALIQIRHDW DQYLVPSDHP KGNFVPQGWV LPPLPSNDIW ATAVKLH (340-485 aa encoded by BC016992 )
PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells. This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis-related protein ES18; ES18; H MGC22015; hES18; MGC22015; Programmed cell death protein 7; U11/U12 snRNP 59K
Gene Aliases: C80112; ES18; HES18; PDCD7
UniProt ID: (Human) Q8N8D1
Entrez Gene ID: (Human) 10081, (Rat) 363082, (Mouse) 50996
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