Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Immunogen sequence: EKEKILLQKR EIESKLFGDP DEFPLAHLLE PFRQYYLQAE HSLPALIQIR HDWDQYLVPS DHPKGNFVPQ GWVLPPLPSN DIWATAVKLH; Positive Samples: HT-29, HeLa, Jurkat, MCF-7, Rat thymus; Cellular Location: Nucleus
PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells. This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis-related protein ES18; ES18; H MGC22015; hES18; MGC22015; Programmed cell death protein 7; U11/U12 snRNP 59K
Gene Aliases: ES18; HES18; PDCD7
UniProt ID: (Human) Q8N8D1
Entrez Gene ID: (Human) 10081, (Rat) 363082
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support