Proteintech

PDI Polyclonal Antibody

PDI Antibody in Immunocytochemistry (ICC/IF)

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PDI Antibody (11245-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using PDI antibody (Product # 11245-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). DAPI (blue).

PDI Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PDI Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11245-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 25 publications 25 publications

Immunohistochemistry (IHC)

View 9 publications 9 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

Immunocytochemistry (ICC/IF)

1:50-1:500

View 12 publications 12 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PDI Fusion Protein Ag1747 (89-273 aa encoded by BC014504)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MTKYKPESE ELTAEWITEF CHRFLEGKIK PHLMSQELPE DWDKQPVKVL VGKNFEDVAF DEKKNVFVEF YAPWCGHCKQ LAPIWDKLGE TYKDHENIVI AKMDSTANEV EAVKVHSFPT LKFFPASADR TVIDYNGERT LDGFKKFLES GGQDGAGDDD DLEDLEEAEE PDMEEDDDQK AVKDEL (89-273 aa encoded by BC014504)

Target Information

Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. It may therefore cause structural modifications of exofacial proteins. Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity). PDI may be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. It also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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NPJ Parkinson's disease

Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H

Tue Mar 07 00:00:00 EST 2023

Deficiency of Perry syndrome-associated p150^Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.

NPJ Parkinson's disease

Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H

Tue Mar 07 00:00:00 EST 2023

MY-1-Loaded Nano-Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early-Stage ECM via a Hsp47-Dependent Mechanism.

Advanced healthcare materials

Yanli Z,Jiayao M,Chunqing Z,Yuting Z,Zhiyan Z,Yulin Z,Minghan L,Longquan S,Dehong Y,Wenjuan Y

Tue Aug 01 00:00:00 EDT 2023

Splice variants of protein disulfide isomerase - identification, distribution and functional characterization in the rat.

Biochimica et biophysica acta. General subjects

Chetot T,Serfaty X,Carret L,Kriznik A,Grand L,Jacolot M,Popowycz F,Benoit E,Lambert V,Lattard V

Wed Feb 01 00:00:00 EST 2023

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.

The Journal of clinical investigation

Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L

Fri Apr 01 00:00:00 EDT 2022

Comparison of mouse and human cytochrome P450 mediated-drug metabolising activities in hepatic and extrahepatic microsomes.

Xenobiotica; the fate of foreign compounds in biological systems

Uehara S,Murayama N,Higuchi Y,Yoneda N,Yamazaki H,Suemizu H

Tue Mar 01 00:00:00 EST 2022

Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism.

Scientific reports

Uehara S,Iida Y,Ida-Tanaka M,Goto M,Kawai K,Yamamoto M,Higuchi Y,Ito S,Takahashi R,Kamimura H,Ito M,Yamazaki H,Oshimura M,Kazuki Y,Suemizu H

Thu Sep 01 00:00:00 EDT 2022

Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.

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Mon Aug 01 00:00:00 EDT 2022

Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.

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Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G

Thu Oct 06 00:00:00 EDT 2022

The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.

Journal of virology

Shi J,Li Z,Xu R,Zhang J,Zhou Q,Gao R,Lu H,Lan Y,Zhao K,He H,Gao F,He W

Wed Jan 12 00:00:00 EST 2022

VWF-Gly2752Ser, a novel non-cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C-terminal dimer formation.

Journal of thrombosis and haemostasis : JTH

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Mon Aug 01 00:00:00 EDT 2022

Transcription of cytochrome P450 46A1 in NIH3T3 cells is negatively regulated by FBS.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Shinohara Y,Ando H,Maekawa M,Arai M,Horibata Y,Satou M,Jojima T,Usui I,Aso Y,Sugimoto H

Wed Jun 01 00:00:00 EDT 2022

A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval.

eLife

Gerondopoulos A,Bräuer P,Sobajima T,Wu Z,Parker JL,Biggin PC,Barr FA,Newstead S

Thu Jun 17 00:00:00 EDT 2021

Porcine Circovirus 2 Manipulates the PERK-ERO1α Axis of the Endoplasmic Reticulum To Favor Its Replication by Derepressing Viral DNA from HMGB1 Sequestration within Nuclei.

Journal of virology

Sun R,Deng Z,Han X,Zhang Y,Zhou Y,Shan Y,Fang W,Li X

Thu Sep 09 00:00:00 EDT 2021

A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.

Molecular metabolism

Chhabra NF,Amend AL,Bastidas-Ponce A,Sabrautzki S,Tarquis-Medina M,Sachs S,Rubey M,Lorenz-Depiereux B,Feuchtinger A,Bakhti M,Lickert H,Przemeck GKH,Hrabě de Angelis M

Wed Dec 01 00:00:00 EST 2021

Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.

Journal of extracellular vesicles

Gao X,Wang Y,Lu F,Chen X,Yang D,Cao Y,Zhang W,Chen J,Zheng L,Wang G,Fu M,Ma L,Song Y,Zhan Q

Mon Mar 01 00:00:00 EST 2021

Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.

Journal of extracellular vesicles

Gao X,Wang Y,Lu F,Chen X,Yang D,Cao Y,Zhang W,Chen J,Zheng L,Wang G,Fu M,Ma L,Song Y,Zhan Q

Mon Mar 01 00:00:00 EST 2021

Sulforaphane Balances Ca²⁺ Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).

Molecular nutrition & food research

Tian S,Lei P,Zhang J,Sun Y,Li B,Shan Y

Thu Jul 01 00:00:00 EDT 2021

The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.

Molecular cell

Sun L,Wang W,Han C,Huang W,Sun Y,Fang K,Zeng Z,Yang Q,Pan Q,Chen T,Luo X,Chen Y

Thu Nov 04 00:00:00 EDT 2021

TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells.

Journal of lipid research

Jung HS,Shimizu-Albergine M,Shen X,Kramer F,Shao D,Vivekanandan-Giri A,Pennathur S,Tian R,Kanter JE,Bornfeldt KE

Wed Jan 01 00:00:00 EST 2020

Mutations in the coat complex II component SEC23B promote colorectal cancer metastasis.

Cell death & disease

Yang C,Chen N,Li X,Lu D,Hou Z,Li Y,Jin Y,Gu J,Yin Y

Mon Mar 02 00:00:00 EST 2020

Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.

European journal of medicinal chemistry

Li B,Yao J,Guo K,He F,Chen K,Lin Z,Liu S,Huang J,Wu Q,Fang M,Zeng J,Wu Z

Thu Oct 15 00:00:00 EDT 2020

Role of Ca²⁺ transients at the node of the mouse embryo in breaking of left-right symmetry.

Science advances

Mizuno K,Shiozawa K,Katoh TA,Minegishi K,Ide T,Ikawa Y,Nishimura H,Takaoka K,Itabashi T,Iwane AH,Nakai J,Shiratori H,Hamada H

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Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.

Scientific reports

Samanta S,Tamura S,Dubeau L,Mhawech-Fauceglia P,Miyagi Y,Kato H,Lieberman R,Buckanovich RJ,Lin YG,Neamati N

Fri Feb 07 00:00:00 EST 2020

Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.

Cell death & disease

Yang L,Zhou X,Sun J,Lei Q,Wang Q,Pan D,Ding M,Ding Y

Thu Sep 17 00:00:00 EDT 2020

Identification and characterization of novel mutations in MOGS in a Chinese patient with infantile spams.

Neurogenetics

Peng X,Luo S,Huang Y,Tan L,Shao J,He X

Wed Apr 01 00:00:00 EDT 2020

Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.

BMC ophthalmology

Chen JL,Hung CT,Keller JJ,Lin HC,Wu YJ

Fri Aug 02 00:00:00 EDT 2019

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.

eLife

Jang I,Pottekat A,Poothong J,Yong J,Lagunas-Acosta J,Charbono A,Chen Z,Scheuner DL,Liu M,Itkin-Ansari P,Arvan P,Kaufman RJ

Tue Jun 11 00:00:00 EDT 2019

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.

eLife

Jang I,Pottekat A,Poothong J,Yong J,Lagunas-Acosta J,Charbono A,Chen Z,Scheuner DL,Liu M,Itkin-Ansari P,Arvan P,Kaufman RJ

Tue Jun 11 00:00:00 EDT 2019

NSP2 forms viroplasms during Dendrolimus punctatus cypovirus infection.

Virology

Xu C,Wang J,Yang J,Lei C,Hu J,Sun X

Mon Jul 01 00:00:00 EDT 2019

Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic β cells.

Molecular and cellular endocrinology

Zhu R,Li X,Xu J,Barrabi C,Kekulandara D,Woods J,Chen X,Liu M

Thu Aug 01 00:00:00 EDT 2019

Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic β cells.

Molecular and cellular endocrinology

Zhu R,Li X,Xu J,Barrabi C,Kekulandara D,Woods J,Chen X,Liu M

Thu Aug 01 00:00:00 EDT 2019

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.

Autophagy

Ni Z,He J,Wu Y,Hu C,Dai X,Yan X,Li B,Li X,Xiong H,Li Y,Li S,Xu L,Li Y,Lian J,He F

Thu Mar 07 00:00:00 EST 2019

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.

Autophagy

Ni Z,He J,Wu Y,Hu C,Dai X,Yan X,Li B,Li X,Xiong H,Li Y,Li S,Xu L,Li Y,Lian J,He F

Thu Mar 07 00:00:00 EST 2019

Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma.

ChemMedChem

Kyani A,Tamura S,Yang S,Shergalis A,Samanta S,Kuang Y,Ljungman M,Neamati N

Mon Jan 22 00:00:00 EST 2018

Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma.

ChemMedChem

Kyani A,Tamura S,Yang S,Shergalis A,Samanta S,Kuang Y,Ljungman M,Neamati N

Mon Jan 22 00:00:00 EST 2018

The dynamic changes of main cell types in the microenvironment of sciatic nerves following sciatic nerve injury and the influence of let-7 on their distribution.

RSC advances

Qian T,Wang P,Chen Q,Yi S,Liu Q,Wang H,Wang S,Geng W,Liu Z,Li S

Fri Dec 07 00:00:00 EST 2018

Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.

Oncotarget

Samanta S,Tamura S,Dubeau L,Mhawech-Fauceglia P,Miyagi Y,Kato H,Lieberman R,Buckanovich RJ,Lin YG,Neamati N

Tue Nov 28 00:00:00 EST 2017

Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.

Oncotarget

Samanta S,Tamura S,Dubeau L,Mhawech-Fauceglia P,Miyagi Y,Kato H,Lieberman R,Buckanovich RJ,Lin YG,Neamati N

Tue Nov 28 00:00:00 EST 2017

Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.

Oncotarget

Samanta S,Tamura S,Dubeau L,Mhawech-Fauceglia P,Miyagi Y,Kato H,Lieberman R,Buckanovich RJ,Lin YG,Neamati N

Tue Nov 28 00:00:00 EST 2017

Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.

Oncotarget

Samanta S,Tamura S,Dubeau L,Mhawech-Fauceglia P,Miyagi Y,Kato H,Lieberman R,Buckanovich RJ,Lin YG,Neamati N

Tue Nov 28 00:00:00 EST 2017

Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.

Oncotarget

Huang YF,Zhu DJ,Chen XW,Chen QK,Luo ZT,Liu CC,Wang GX,Zhang WJ,Liao NZ

Tue Jun 20 00:00:00 EDT 2017

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

International journal of molecular sciences

Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ

Thu Oct 27 00:00:00 EDT 2016

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

International journal of molecular sciences

Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ

Thu Oct 27 00:00:00 EDT 2016

Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle.

JCI insight

Hammers DW,Sleeper MM,Forbes SC,Coker CC,Jirousek MR,Zimmer M,Walter GA,Sweeney HL

Thu Dec 22 00:00:00 EST 2016

Expression of prolyl 4-hydroxylase beta-polypeptide in non-small cell lung cancer treated with Chinese medicines.

Chinese journal of integrative medicine

Wang SM,Lin LZ,Zhou DH,Zhou JX,Xiong SQ

Tue Sep 01 00:00:00 EDT 2015

Expression of prolyl 4-hydroxylase beta-polypeptide in non-small cell lung cancer treated with Chinese medicines.

Chinese journal of integrative medicine

Wang SM,Lin LZ,Zhou DH,Zhou JX,Xiong SQ

Tue Sep 01 00:00:00 EDT 2015

Expression of prolyl 4-hydroxylase beta-polypeptide in non-small cell lung cancer treated with Chinese medicines.

Chinese journal of integrative medicine

Wang SM,Lin LZ,Zhou DH,Zhou JX,Xiong SQ

Tue Sep 01 00:00:00 EDT 2015

Expression of prolyl 4-hydroxylase beta-polypeptide in non-small cell lung cancer treated with Chinese medicines.

Chinese journal of integrative medicine

Wang SM,Lin LZ,Zhou DH,Zhou JX,Xiong SQ

Tue Sep 01 00:00:00 EDT 2015

Halofuginone improves muscle-cell survival in muscular dystrophies.

Biochimica et biophysica acta

Bodanovsky A,Guttman N,Barzilai-Tutsch H,Genin O,Levy O,Pines M,Halevy O

Tue Jul 01 00:00:00 EDT 2014

Halofuginone improves muscle-cell survival in muscular dystrophies.

Biochimica et biophysica acta

Bodanovsky A,Guttman N,Barzilai-Tutsch H,Genin O,Levy O,Pines M,Halevy O

Tue Jul 01 00:00:00 EDT 2014

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Nature

Song K,Nam YJ,Luo X,Qi X,Tan W,Huang GN,Acharya A,Smith CL,Tallquist MD,Neilson EG,Hill JA,Bassel-Duby R,Olson EN

Sun May 13 00:00:00 EDT 2012

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Nature

Song K,Nam YJ,Luo X,Qi X,Tan W,Huang GN,Acharya A,Smith CL,Tallquist MD,Neilson EG,Hill JA,Bassel-Duby R,Olson EN

Sun May 13 00:00:00 EDT 2012

Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Nature

Song K,Nam YJ,Luo X,Qi X,Tan W,Huang GN,Acharya A,Smith CL,Tallquist MD,Neilson EG,Hill JA,Bassel-Duby R,Olson EN

Sun May 13 00:00:00 EDT 2012

Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.

PloS one

Spector I,Zilberstein Y,Lavy A,Nagler A,Genin O,Pines M

Tue Apr 09 00:00:00 EDT 2013

Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.

PloS one

Spector I,Zilberstein Y,Lavy A,Nagler A,Genin O,Pines M

Tue Apr 09 00:00:00 EDT 2013

Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling.

Circulation research

Smith CL,Baek ST,Sung CY,Tallquist MD

Fri Jun 10 00:00:00 EDT 2011

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis.

Cell cycle (Georgetown, Tex.)

Castello-Cros R,Whitaker-Menezes D,Molchansky A,Purkins G,Soslowsky LJ,Beason DP,Sotgia F,Iozzo RV,Lisanti MP

Fri Jul 01 00:00:00 EDT 2011

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis.

Cell cycle (Georgetown, Tex.)

Castello-Cros R,Whitaker-Menezes D,Molchansky A,Purkins G,Soslowsky LJ,Beason DP,Sotgia F,Iozzo RV,Lisanti MP

Fri Jul 01 00:00:00 EDT 2011

Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.

The Journal of biological chemistry

Meissner M,Weissgerber P,Londoño JE,Prenen J,Link S,Ruppenthal S,Molkentin JD,Lipp P,Nilius B,Freichel M,Flockerzi V

Fri May 06 00:00:00 EDT 2011

Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.

The Journal of biological chemistry

Meissner M,Weissgerber P,Londoño JE,Prenen J,Link S,Ruppenthal S,Molkentin JD,Lipp P,Nilius B,Freichel M,Flockerzi V

Fri May 06 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: CaO19.12595; Cellular thyroid hormone-binding protein; collagen prolyl 4-hydroxylase beta; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; glutathione-insulin transhydrogenase; p55; PDI; PDI1P; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase, beta polypeptide; protein disulfide isomerase; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase family A, member 1; protein disulfide isomerase-associated 1; protein disulfide isomerase/oxidoreductase; Protein disulfide-isomerase; protocollagen hydroxylase; testicular secretory protein Li 32; thyroid hormone-binding protein p55

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Gene Aliases: CLCRP1; DSI; ERBA2L; ERp59; GIT; P4HB; P4Hbeta; PDI; PDIA1; PDIR; PHDB; PO4DB; PO4HB; PROHB; Thbp

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UniProt ID: (Human) P07237, (Rat) P04785, (Mouse) P09103

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Entrez Gene ID: (Human) 5034, (Rat) 25506, (Mouse) 18453

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Function(s)

protein disulfide isomerase activity procollagen-proline 4-dioxygenase activity integrin binding protein binding enzyme binding poly(A) RNA binding protein heterodimerization activity peptidyl-proline 4-dioxygenase activity isomerase activity chaperone

Process(es)

response to reactive oxygen species protein folding peptidyl-proline hydroxylation to 4-hydroxy-L-proline response to endoplasmic reticulum stress lipoprotein biosynthetic process cell redox homeostasis positive regulation of viral entry into host cell cellular response to hypoxia regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PDI Polyclonal Antibody

PDI Antibody (11245-1-AP) in ICC/IF

Product Details

11245-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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