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PIK3R4 Antibody (MA5-38596) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of PIK3R4 in HeLa cells using PIK3R4 Monoclonal Antibody (Product # MA5-38596) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503)
Product Details
MA5-38596
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
5H3A11
Immunogen
Purified recombinant fragment of human PIK3R4 (aa: 772-906) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898508
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: phosphatidylinositol 3-kinase-associated p150; Phosphoinositide 3-kinase adaptor protein; Phosphoinositide 3-kinase regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4, p150; PI3-Kinase p150; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3-kinase VPS15
Gene Aliases: p150; PIK3R4; VPS15
UniProt ID: (Human) Q99570
Entrez Gene ID: (Human) 30849
protein phosphorylation
protein targeting to vacuole
phosphatidylinositol biosynthetic process
macroautophagy
pexophagy
regulation of cytokinesis
receptor catabolic process
toll-like receptor 9 signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
cellular response to glucose starvation
positive regulation of phosphatidylinositol 3-kinase activity
late endosome to vacuole transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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