Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-18594
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (KHSQSRRPSSWRQEKITR) corresponding to the internal amino acids of PIN1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10982747
Product Specific Information
This antibody is predicted to react with canine, human and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: EC 5.2.1.8; NIMA-interacting; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1
Gene Aliases: DOD; PIN1; UBL5
UniProt ID: (Human) Q13526
Entrez Gene ID: (Human) 5300, (Rat) 298696
protein peptidyl-prolyl isomerization
positive regulation of protein phosphorylation
cell cycle
regulation of mitotic nuclear division
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
regulation of cytokinesis
negative regulation of type I interferon production
positive regulation of protein dephosphorylation
negative regulation of protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
synapse organization
protein stabilization
positive regulation of ubiquitin-protein transferase activity
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of cell growth involved in cardiac muscle cell development
negative regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway
regulation of protein localization to nucleus
regulation of signal transduction by p53 class mediator
negative regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support