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PITRM1 Antibody (PA5-52340) in IHC
Immunohistochemical staining of PITRM1 in human cerebral cortex, colon, heart muscle and testis using PITRM1 Polyclonal Antibody (Product # PA5-52340) (A) shows similar protein distribution across tissues to an independent PITRM1 Polyclonal Antibody (B).
Product Details
PA5-52340
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PITRM1. Recombinant protein control fragment (Product #RP-89249).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645586
Product Specific Information
Immunogen sequence: LEHTVLCGSQ KYPCRDPFFK MLNRSLSTFM NAFTASDYTL YPFSTQNPKD FQNLLSVYLD ATFFPCLREL DFWQEGWRLE HENPSDPQTP LVFKGVVFNE MKGAFTDNER IFSQHLQNRL LPDHTYSVVS
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.
Target Information
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPreP; Metalloprotease 1; metalloprotease 1 (pitrilysin family); nuclear transplantation upregulated protein 1; pitrilysin metallepetidase 1; pitrilysin metalloprotease 1; Pitrilysin metalloproteinase 1; PreP peptidasome; Presequence protease, mitochondrial
Gene Aliases: 2310012C15Rik; AA410010; KIAA1104; mKIAA1104; MP-1; MP1; Ntup1; PITRM1; PREP
UniProt ID: (Human) Q5JRX3, (Mouse) Q8K411
Entrez Gene ID: (Human) 10531, (Mouse) 69617, (Rat) 307081
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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