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Product Details
H00010531-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1H3
Immunogen
PITRM1 (AAH01150, 1 a.a. approximately 534 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MRPDDKYHEK QAQVEATKLK QKVEALSPGD RQQIYEKGLE LRSQQSKPQD ASCLPALKVS DIEPTIPVTE LDVVLTAGDI PVQYCAQPTN GMVYFRAFSS LNTLPEELRP YVPLFCSVLT KLGCGLLDYR EQAQQIELKT GGMSASPHVL PDDSHMDTYE QGVLFSSLCL DRNLPDMMQL WSEIFNNPCF EEEEHFKVLV KMTAQELANG IPDSGHLYAS IRAGRTLTPA GDLQETFSGM DQVRLMKRIA EMTDIKPILR KLPRIKKHLL NGDNMRCSVN ATPQQMPQTE KAVEDFLRSI GRSKKERRPV RPHTVEKPVP SSSGGDAHVP HGSQVIRKLV MEPTFKPWQM KTHFLMPFPV NYVGECIRTV PYTDPDHASL KILARLMTAK FLHTEIREKG GAYGGGAKLS HNGIFTLYSY RDPNTIETLQ SFGKAVDWAK SGKFTQQDID EAKLSVFSTV DAPVAPSDKG MDHFLYGLSD EMKQAHREQL FAVSHDKLLA VSDRYLGTGK STHGLAILGP ENPKIAKDPS WIIR
Target Information
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPreP; Metalloprotease 1; metalloprotease 1 (pitrilysin family); Pitrilysin metalloproteinase 1; PreP peptidasome; Presequence protease, mitochondrial
Gene Aliases: KIAA1104; MP1; PITRM1; PREP
UniProt ID: (Human) Q5JRX3
Entrez Gene ID: (Human) 10531
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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