Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: KTTTVNYVRD TLSNPRGWMA LLLDQETYSL QSENLWINRS LQYSATFDNF APGNYLLLVH TDLPPYPDIL LRCGSRVGLS FPFLPSPGQN Q
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 26%.
The protein encoded by this gene is predicted to have a single transmembrane (TM)-spanning domain and multiple copies of an immunoglobulin-like plexin-transcription-factor domain. Alternative splicing results in two transcript variants encoding different isoforms. Other alternatively spliced transcripts have been described, but the full length sequences have not been determined. Several of these transcripts are predicted to encode truncated products which lack the TM and may be secreted. Mutations in this gene cause autosomal recessive polycystic kidney disease, also known as polycystic kidney and hepatic disease-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AI118496; AI182499; Fibrocystin; Polycystic kidney and hepatic disease 1 protein; Polyductin; TIG multiple domains 1; Tigmin
Gene Aliases: ARPKD; FCYT; PKHD1; TIGM1
UniProt ID: (Human) P08F94
Entrez Gene ID: (Human) 5314
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support