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Invitrogen
PKP3 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
PKP3 Antibody (PA5-84574)
Relative expression in different tissues in IHC: Detection of differential expression levels of PKP3 demonstrates antibody specificity. Immunohistochemical analysis of PKP3 using anti-PKP3 Polyclonal Antibody (Product #PA5-84574), shows significant staining of PKP3 in skin and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of PKP3 within each tissue is shown using... View More
Product Details
PA5-84574
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PKP3. Recombinant protein control fragment (Product #RP-104169).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791725
Product Specific Information
Immunogen sequence: FDDIDLPSAV KYLMASDPNL QVLGAAYIQH KCYSDAAAKK QARSLQAVPR LVKLFNHANQ EVQRHATGAM RNLI
Target Information
Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plakophilin 3b; Plakophilin-3
Gene Aliases: PKP3
UniProt ID: (Human) Q9Y446
Entrez Gene ID: (Human) 11187
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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