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A suggested positive control is rat brain tissue lysate.
PA5-34457 can be used with blocking peptide PEP-1499.
The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
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Protein Aliases: C2H2-type zinc finger protein; pleiomorphic adenoma gene-like 2; Pleiomorphic adenoma-like protein 2; pleomorphic adenoma gene like 2; Zinc finger protein PLAGL2
Gene Aliases: AU018672; AW552839; KIAA0198; mKIAA0198; PLAGL2; ZNF900
UniProt ID: (Human) Q9UPG8
Entrez Gene ID: (Human) 5326, (Mouse) 54711, (Rat) 296281
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