Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 130kDa-Ins(1,4,5)P3 binding protein; Inactive phospholipase C-like protein 1; p130; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; Phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; Phospholipase C-related but catalytically inactive protein; PLC-L1; PRIP; PRIP1; protein phosphatase 1, regulatory subunit 127
Gene Aliases: C230017K02Rik; PLC-L; PLC-L1; PLCE; PLCL; PLCL1; PLDL1; PPP1R127; PRIP; PRIP-1
UniProt ID: (Human) Q15111, (Mouse) Q3USB7, (Rat) Q62688
Entrez Gene ID: (Human) 5334, (Mouse) 227120, (Rat) 84587
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support