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PLGF Antibody (BS-0281R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded human colon cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with PLGF Polyclonal Antibody, Unconjugated (bs-0281R) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes ... View More
Product Details
BS-0281R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PLGF, amino acids 166-221.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family. PlGF is a pleiotropic factor affects different cell types and regulates various biological responses. The activity of vascular endothelial growth factor (VEGF), which is the most potent of all angiogenic mediators, is partly modulated by PlGF. It plays a major role in vasculogenesis and angiogenesis in human placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein; PlGF; PlGF 1; SHGC
Gene Aliases: D12S1900; PGF; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760
UniProt ID: (Human) P49763
Entrez Gene ID: (Human) 5228
branching involved in ureteric bud morphogenesis
response to hypoxia
positive regulation of endothelial cell proliferation
sprouting angiogenesis
signal transduction
cell-cell signaling
female pregnancy
positive regulation of cell proliferation
cell differentiation
organ regeneration
cellular response to hormone stimulus
response to drug
positive regulation of angiogenesis
vascular endothelial growth factor receptor signaling pathway
positive regulation of cell division
regulation of morphogenesis of a branching structure
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