Product References
Polo-like kinase-1 mediates hepatitis C virus-induced cell migration, a drug target for liver cancer.
Life science alliance
El-Khobar KE,Tay E,Diefenbach E,Gloss BS,George J,Douglas MW
37-7100 was used in Immunocytochemistry-immunofluorescence to identify PLK1 as the mediating kinase.
Wed Nov 01 00:00:00 EDT 2023
Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation.
Cell reports
Xu L,Ali M,Duan W,Yuan X,Garba F,Mullen M,Sun B,Poser I,Duan H,Lu J,Tian R,Ge Y,Chu L,Pan W,Wang D,Hyman A,Green H,Li L,Dou Z,Liu D,Liu X,Yao X
37-7100 was used in Immunocytochemistry to identify Apolo1 as a tuner of PLK1 needed for correct kinetochore-microtubule attachments during cell division.
Tue Jul 13 00:00:00 EDT 2021
Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation.
Cell reports
Xu L,Ali M,Duan W,Yuan X,Garba F,Mullen M,Sun B,Poser I,Duan H,Lu J,Tian R,Ge Y,Chu L,Pan W,Wang D,Hyman A,Green H,Li L,Dou Z,Liu D,Liu X,Yao X
37-7100 was used in Immunocytochemistry to identify Apolo1 as a tuner of PLK1 needed for correct kinetochore-microtubule attachments during cell division.
Tue Jul 13 00:00:00 EDT 2021
Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.
The EMBO journal
Han H,Davidson LA,Fan YY,Goldsby JS,Yoon G,Jin UH,Wright GA,Landrock KK,Weeks BR,Wright RC,Allred CD,Jayaraman A,Ivanov I,Roper J,Safe SH,Chapkin RS
37-7100 was used in Western Blot to indicate that the AhR-FoxM1 axis, at least in part, mediates colonic stem/progenitor cell behavior.
Thu Oct 01 00:00:00 EDT 2020
Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.
The EMBO journal
Han H,Davidson LA,Fan YY,Goldsby JS,Yoon G,Jin UH,Wright GA,Landrock KK,Weeks BR,Wright RC,Allred CD,Jayaraman A,Ivanov I,Roper J,Safe SH,Chapkin RS
37-7100 was used in Western Blot to indicate that the AhR-FoxM1 axis, at least in part, mediates colonic stem/progenitor cell behavior.
Thu Oct 01 00:00:00 EDT 2020
O-GlcNAcylation of myosin phosphatase targeting subunit 1 (MYPT1) dictates timely disjunction of centrosomes.
The Journal of biological chemistry
Liu C,Shi Y,Li J,Liu X,Xiahou Z,Tan Z,Chen X,Li J
37-7100 was used in Immunoprecipitation to conclude that under high O-GlcNAc levels, PLK1 is untimely activated, conducive to inopportune centrosome separation and disruption of the cell cycle. We propose that too much O-GlcNAc is equally deleterious as too little O-GlcNAc, and a fine balance between the OGT/OGA duo is indispensable for successful mitotic divisions.
Fri May 22 00:00:00 EDT 2020
A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis.
Journal of cell science
Adam K,Cartel M,Lambert M,David L,Yuan L,Besson A,Mayeux P,Manenti S,Didier C
37-7100 was used in Proximity Ligation Assay to study the DNA damage response-independent roles of CHK1.
Fri Aug 10 00:00:00 EDT 2018
Albatross/FBF1 contributes to both centriole duplication and centrosome separation.
Genes to cells : devoted to molecular & cellular mechanisms
Inoko A,Yano T,Miyamoto T,Matsuura S,Kiyono T,Goshima N,Inagaki M,Hayashi Y
Published figure using PLK1 monoclonal antibody (Product # 37-7100) in Immunofluorescence
Sat Dec 01 00:00:00 EST 2018
Separase Inhibitor Sepin-1 Inhibits Foxm1 Expression and Breast Cancer Cell Growth.
Journal of cancer science & therapy
Zhang N,Pati D
37-7100 was used in Western Blotting to report that Sepin-1 hinders growth of breast cancer cells, cell migration, and wound healing.
Wed Sep 30 00:00:00 EDT 2020
Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.
Cell metabolism
Shirakawa J,Fernandez M,Takatani T,El Ouaamari A,Jungtrakoon P,Okawa ER,Zhang W,Yi P,Doria A,Kulkarni RN
37-7100 was used in Immunohistochemistry to provide evidence for the involvement of the insulin-FoxM1/PLK1/CENP-A pathway in regulating pancreatic Β cell cell-cycle progression.
Tue Apr 04 00:00:00 EDT 2017
Phosphorylation of PP1 Regulator Sds22 by PLK1 Ensures Accurate Chromosome Segregation.
The Journal of biological chemistry
Duan H,Wang C,Wang M,Gao X,Yan M,Akram S,Peng W,Zou H,Wang D,Zhou J,Chu Y,Dou Z,Barrett G,Green HN,Wang F,Tian R,He P,Wang W,Liu X,Yao X
Published figure using PLK1 monoclonal antibody (Product # 37-7100) in Immunoprecipitation
Fri Sep 30 00:00:00 EDT 2016
Phosphorylation of PP1 Regulator Sds22 by PLK1 Ensures Accurate Chromosome Segregation.
The Journal of biological chemistry
Duan H,Wang C,Wang M,Gao X,Yan M,Akram S,Peng W,Zou H,Wang D,Zhou J,Chu Y,Dou Z,Barrett G,Green HN,Wang F,Tian R,He P,Wang W,Liu X,Yao X
Published figure using PLK1 monoclonal antibody (Product # 37-7100) in Immunoprecipitation
Fri Sep 30 00:00:00 EDT 2016
Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling.
eLife
Wu J,Ivanov AI,Fisher PB,Fu Z
37-7100 was used in western blot to research induction of epithelial-to-mesenchymal transition by Polo-like kinase 1 and promotion of epithelial cell motility by activating CRAF/ERK signaling
Tue Mar 22 00:00:00 EDT 2016
FOXM1 and polo-like kinase 1 are co-ordinately overexpressed in patients with gastric adenocarcinomas.
BMC research notes
Dibb M,Han N,Choudhury J,Hayes S,Valentine H,West C,Sharrocks AD,Ang YS
37-7100 was used in immunohistochemistry to study co-expression of of FOXM1 and polo-like kinase 1 in gastric adenocarcinoma patients
Sat Nov 14 00:00:00 EST 2015
Calmodulin activation of polo-like kinase 1 is required during mitotic entry.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Dai G,Qian Y,Chen J,Meng FL,Pan FY,Shen WG,Zhang SZ,Xue B,Li CJ
Tue Oct 01 00:00:00 EDT 2013
Calmodulin activation of polo-like kinase 1 is required during mitotic entry.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Dai G,Qian Y,Chen J,Meng FL,Pan FY,Shen WG,Zhang SZ,Xue B,Li CJ
Tue Oct 01 00:00:00 EDT 2013
Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.
International journal of cancer
Ito T,Sato F,Kan T,Cheng Y,David S,Agarwal R,Paun BC,Jin Z,Olaru AV,Hamilton JP,Selaru FM,Yang J,Matsumura N,Shimizu K,Abraham JM,Shimada Y,Mori Y,Meltzer SJ
37-7100 was used in western blot to determine the function and regulation of polo-like kinase 1 in esophageal cancer.
Tue Nov 01 00:00:00 EDT 2011
Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.
International journal of cancer
Ito T,Sato F,Kan T,Cheng Y,David S,Agarwal R,Paun BC,Jin Z,Olaru AV,Hamilton JP,Selaru FM,Yang J,Matsumura N,Shimizu K,Abraham JM,Shimada Y,Mori Y,Meltzer SJ
37-7100 was used in western blot to determine the function and regulation of polo-like kinase 1 in esophageal cancer.
Tue Nov 01 00:00:00 EDT 2011
Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure.
Hepatology (Baltimore, Md.)
Chen F,Ohashi N,Li W,Eckman C,Nguyen JH
Published figure using PLK1 monoclonal antibody (Product # 37-7100) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2009