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Product Details
PA5-112654
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Plexin-B2 protein (1080-1200AA)
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867389
Target Information
Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: differentially expressed in brain tumors; MM1; MM1KIAA0315dJ402G11.3; Plexin-B2
Gene Aliases: Debt; dJ402G11.3; KIAA0315; MM1; Nbla00445; PLEXB2; plexin-B2; PLXNB2
UniProt ID: (Human) O15031, (Mouse) B2RXS4
Entrez Gene ID: (Human) 23654, (Mouse) 140570
neural tube closure
regulation of protein phosphorylation
signal transduction
multicellular organism development
neuroblast proliferation
brain development
regulation of cell shape
regulation of GTPase activity
positive regulation of axonogenesis
semaphorin-plexin signaling pathway
regulation of neuron migration
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
positive regulation of neuron projection development
regulation of cell migration
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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