Product References
Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23.
iScience
Newton S,Aguilar C,Bunton-Stasyshyn RK,Flook M,Stewart M,Marcotti W,Brown S,Bowl MR
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Immunoprecipitation
Fri Oct 20 00:00:00 EDT 2023
Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells.
Cellular and molecular life sciences : CMLS
Sanchez-Collado J,Lopez JJ,Jardin I,Berna-Erro A,Camello PJ,Cantonero C,Smani T,Salido GM,Rosado JA
MA3-914 was used in Western Blot to the role of Orai1α and Orai1β (canonical pore-forming subunit of the Ca2+ release-activated Ca2+ (CRAC) channel) variants in the activation of TRPC1 in HeLa cells.
Thu Jan 06 00:00:00 EST 2022
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
Cell death & disease
Bachmann M,Rossa A,Varanita T,Fioretti B,Biasutto L,Milenkovic S,Checchetto V,Peruzzo R,Ahmad SA,Patel SH,Lukowski R,Edwards MJ,Ceccarelli M,Gulbins E,Zoratti M,Mattarei A,Szabo I
MA3-914 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to identify mitochondrial KCa3.1 as an unexpected player in cancer cell migration and show that its pharmacological targeting is efficient against both tumor growth and metastatic spread in vivo.
Tue Dec 20 00:00:00 EST 2022
Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.
PLoS genetics
Newton S,Kong F,Carlton AJ,Aguilar C,Parker A,Codner GF,Teboul L,Wells S,Brown SDM,Marcotti W,Bowl MR
MA3-914 was used in Immunohistochemistry to elaborate upon the role of the neural cell adhesion molecule Neuroplastin in mammalian hearing.
Sat Jan 01 00:00:00 EST 2022
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model.
Journal of experimental & clinical cancer research : CR
Severin F,Urbani A,Varanita T,Bachmann M,Azzolini M,Martini V,Pizzi M,Tos APD,Frezzato F,Mattarei A,Ghia P,Bertilaccio MTS,Gulbins E,Paradisi C,Zoratti M,Semenzato GC,Leanza L,Trentin L,Szabò I
MA3-914 was used in Western Blot to evaluated the effect of the mitoKv1.3 inhibitor PAPTP and IKCa targeting TRAM-34 in chronic lymphocytic leukemia cells from ibrutinib-resistant patients and in combination with Venetoclax.
Wed Feb 16 00:00:00 EST 2022
Uptake mechanism of iron-phytosiderophore from the soil based on the structure of yellow stripe transporter.
Nature communications
Yamagata A,Murata Y,Namba K,Terada T,Fukai S,Shirouzu M
MA3-914 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to present three cryo-electron microscopy structures of barley YS1 (HvYS1) in the apo state, in complex with an iron-phytosiderophore complex, Fe(III)-deoxymugineic acid (Fe(III)-DMA), and in complex with the iron-bound synthetic DMA analog (Fe(III)-PDMA).
Wed Nov 23 00:00:00 EST 2022
UBIAD1 and CoQ10 protect melanoma cells from lipid peroxidation-mediated cell death.
Redox biology
Arslanbaeva L,Tosi G,Ravazzolo M,Simonato M,Tucci FA,Pece S,Cogo P,Santoro MM
MA3-914 was used in Western Blotting to provide evidence that UBIAD1 expression is associated with poor overall survival (OS) in human melanoma patients.
Sun May 01 00:00:00 EDT 2022
Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation.
Cancers
Sanchez-Collado J,Nieto-Felipe J,Jardin I,Bhardwaj R,Berna-Erro A,Salido GM,Smani T,Hediger MA,Lopez JJ,Rosado JA
MA3-914 was used in Western Blotting to show that treatment of non-tumoral breast epithelial cells with tunicamycin attenuates SOCE.
Thu Dec 29 00:00:00 EST 2022
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Neuron
Kuijpers M,Kochlamazashvili G,Stumpf A,Puchkov D,Swaminathan A,Lucht MT,Krause E,Maritzen T,Schmitz D,Haucke V
MA3-914 was used in Western Blot, Immunohistochemistry to demonstrate that loss of neuronal autophagy causes selective accumulation of tubular endoplasmic reticulum (ER) in axons, resulting in increased excitatory neurotransmission and compromised postnatal viability in vivo.
Wed Jan 20 00:00:00 EST 2021
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Neuron
Kuijpers M,Kochlamazashvili G,Stumpf A,Puchkov D,Swaminathan A,Lucht MT,Krause E,Maritzen T,Schmitz D,Haucke V
MA3-914 was used in Western Blot, Immunohistochemistry to demonstrate that loss of neuronal autophagy causes selective accumulation of tubular endoplasmic reticulum (ER) in axons, resulting in increased excitatory neurotransmission and compromised postnatal viability in vivo.
Wed Jan 20 00:00:00 EST 2021
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.
Neuron
Kuijpers M,Kochlamazashvili G,Stumpf A,Puchkov D,Swaminathan A,Lucht MT,Krause E,Maritzen T,Schmitz D,Haucke V
MA3-914 was used in Western Blot, Immunohistochemistry to demonstrate that loss of neuronal autophagy causes selective accumulation of tubular endoplasmic reticulum (ER) in axons, resulting in increased excitatory neurotransmission and compromised postnatal viability in vivo.
Wed Jan 20 00:00:00 EST 2021
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
EMBO molecular medicine
Birolini G,Valenza M,Di Paolo E,Vezzoli E,Talpo F,Maniezzi C,Caccia C,Leoni V,Taroni F,Bocchi VD,Conforti P,Sogne E,Petricca L,Cariulo C,Verani M,Caricasole A,Falqui A,Biella G,Cattaneo E
MA3-914 was used in Immunohistochemistry to indicate that cholesterol infusion to the striatum can exert a dose-dependent, disease-modifying effect and may be therapeutically relevant in HD.
Wed Oct 07 00:00:00 EDT 2020
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
EMBO molecular medicine
Birolini G,Valenza M,Di Paolo E,Vezzoli E,Talpo F,Maniezzi C,Caccia C,Leoni V,Taroni F,Bocchi VD,Conforti P,Sogne E,Petricca L,Cariulo C,Verani M,Caricasole A,Falqui A,Biella G,Cattaneo E
MA3-914 was used in Immunohistochemistry to indicate that cholesterol infusion to the striatum can exert a dose-dependent, disease-modifying effect and may be therapeutically relevant in HD.
Wed Oct 07 00:00:00 EDT 2020
Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer.
Cancers
Sritangos P,Pena Alarcon E,James AD,Sultan A,Richardson DA,Bruce JIE
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Western Blot
Thu Jan 16 00:00:00 EST 2020
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
eLife
Abildgaard AB,Stein A,Nielsen SV,Schultz-Knudsen K,Papaleo E,Shrikhande A,Hoffmann ER,Bernstein I,Gerdes AM,Takahashi M,Ishioka C,Lindorff-Larsen K,Hartmann-Petersen R
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Western Blot
Thu Nov 07 00:00:00 EST 2019
Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+ -transporters in heart failure.
Journal of cellular and molecular medicine
Olgar Y,Durak A,Tuncay E,Bitirim CV,Ozcinar E,Inan MB,Tokcaer-Keskin Z,Akcali KC,Akar AR,Turan B
MA3-914 was used in Immunocytochemistry-immunoflourescence to examine a possible role of Zn2+ -transporters in the development of heart failure via induction of endoplasmic reticulum stress.
Thu Mar 01 00:00:00 EST 2018
The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner.
Cells
Roest G,Hesemans E,Welkenhuyzen K,Luyten T,Engedal N,Bultynck G,Parys JB
MA3-914 was used in Western Blotting to assess the effect of endoplasmic reticulum stress on autophagy and Ca2+ homeostasis.
Fri Nov 30 00:00:00 EST 2018
Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance.
Neuron
Schmidt N,Kollewe A,Constantin CE,Henrich S,Ritzau-Jost A,Bildl W,Saalbach A,Hallermann S,Kulik A,Fakler B,Schulte U
MA3-914 was used in Western Blotting to establish neuroplastin and basigin as obligatory auxiliary subunits of native plasma membrane Ca2+-ATPases and key regulators of intracellular Ca2+ concentration.
Wed Nov 15 00:00:00 EST 2017
Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease.
Molecular psychiatry
Pérez-Cañamás A,Benvegnù S,Rueda CB,Rábano A,Satrústegui J,Ledesma MD
MA3914 was used in western blot to investigate how sphingomyelin influence neural pathology in a mouse model of Niemann-Pick disease type A
Mon May 01 00:00:00 EDT 2017
Role of STIM1 in the surface expression of SARAF.
Channels (Austin, Tex.)
Albarran L,Regodón S,Salido GM,Lopez JJ,Rosado JA
MA3914 was used in western blot to elucidate how SARAF influences the location of STIM1
Mon Jan 02 00:00:00 EST 2017
Glutamate Deregulation in Ketamine-Induced Psychosis-A Potential Role of PSD95, NMDA Receptor and PMCA Interaction.
Frontiers in cellular neuroscience
Lisek M,Ferenc B,Studzian M,Pulaski L,Guo F,Zylinska L,Boczek T
Thu Oct 01 00:00:00 EDT 2020
Ca2+ removal by the plasma membrane Ca2+-ATPase influences the contribution of mitochondria to activity-dependent Ca2+ dynamics in Aplysia neuroendocrine cells.
Journal of neurophysiology
Groten CJ,Rebane JT,Hodgson HM,Chauhan AK,Blohm G,Magoski NS
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Immunocytochemistry
Wed Jun 01 00:00:00 EDT 2016
Estrogen Enhances Linkage in the Vascular Endothelial Calmodulin Network via a Feedforward Mechanism at the G Protein-coupled Estrogen Receptor 1.
The Journal of biological chemistry
Tran QK,Firkins R,Giles J,Francis S,Matnishian V,Tran P,VerMeer M,Jasurda J,Burgard MA,Gebert-Oberle B
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Western Blot
Fri May 13 00:00:00 EDT 2016
Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation.
Molecular vision
Chaney SY,Mukherjee S,Giddabasappa A,Rueda EM,Hamilton WR,Johnson JE,Fox DA
MA3914 was used in immunohistochemistry - frozen section to examine the effects of retinal progenitor cell proliferation on the spatiotemporal differentiation and synaptic development of rods and bipolar cells in early postnatal gestational lead exposure retinas
Mon Jan 29 00:00:00 EST 2018
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice.
EMBO molecular medicine
Valenza M,Chen JY,Di Paolo E,Ruozi B,Belletti D,Ferrari Bardile C,Leoni V,Caccia C,Brilli E,Di Donato S,Boido MM,Vercelli A,Vandelli MA,Forni F,Cepeda C,Levine MS,Tosi G,Cattaneo E
MA3-914 was used in immunohistochemistry to investigate the effects of cholesterol supplementation in a mouse model of Huntington's disease
Tue Dec 01 00:00:00 EST 2015
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.
Nature communications
Sharma P,Abbasi C,Lazic S,Teng ACT,Wang D,Dubois N,Ignatchenko V,Wong V,Liu J,Araki T,Tiburcy M,Ackerley C,Zimmermann WH,Hamilton R,Sun Y,Liu PP,Keller G,Stagljar I,Scott IC,Kislinger T,Gramolini AO
MA3-914 was used in western blot to investigate the impact of Tmem65 on heart development
Fri Sep 25 00:00:00 EDT 2015
Hetero-oligomeric Complex between the G Protein-coupled Estrogen Receptor 1 and the Plasma Membrane Ca2+-ATPase 4b.
The Journal of biological chemistry
Tran QK,VerMeer M,Burgard MA,Hassan AB,Giles J
MA3-914 was used in immunocytochemistry, immunoprecipitation, and western blot to show that PMCA and GPER/GPR30 physically interact and explore how they functionally influence each other.
Fri May 22 00:00:00 EDT 2015
Hetero-oligomeric Complex between the G Protein-coupled Estrogen Receptor 1 and the Plasma Membrane Ca2+-ATPase 4b.
The Journal of biological chemistry
Tran QK,VerMeer M,Burgard MA,Hassan AB,Giles J
MA3-914 was used in immunocytochemistry, immunoprecipitation, and western blot to show that PMCA and GPER/GPR30 physically interact and explore how they functionally influence each other.
Fri May 22 00:00:00 EDT 2015
Hetero-oligomeric Complex between the G Protein-coupled Estrogen Receptor 1 and the Plasma Membrane Ca2+-ATPase 4b.
The Journal of biological chemistry
Tran QK,VerMeer M,Burgard MA,Hassan AB,Giles J
MA3-914 was used in immunocytochemistry, immunoprecipitation, and western blot to show that PMCA and GPER/GPR30 physically interact and explore how they functionally influence each other.
Fri May 22 00:00:00 EDT 2015
Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology.
Biochimica et biophysica acta
Berrocal M,Corbacho I,Vázquez-Hernández M,Ávila J,Sepúlveda MR,Mata AM
MA3-914 was used in Immunohistochemistry to identify a link between Ca2+-transporters, aging and neurodegeneration mediated by tau protein.
Wed Jul 01 00:00:00 EDT 2015
Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology.
Biochimica et biophysica acta
Berrocal M,Corbacho I,Vázquez-Hernández M,Ávila J,Sepúlveda MR,Mata AM
MA3-914 was used in Immunohistochemistry to identify a link between Ca2+-transporters, aging and neurodegeneration mediated by tau protein.
Wed Jul 01 00:00:00 EDT 2015
TRPC6 participates in the regulation of cytosolic basal calcium concentration in murine resting platelets.
Biochimica et biophysica acta
Albarran L,Berna-Erro A,Dionisio N,Redondo PC,Lopez E,Lopez JJ,Salido GM,Brull Sabate JM,Rosado JA
MA3-914 was used in western blot to study the mechanism by which TRPC6 contributes to platelet calcium homeostasis
Tue Apr 01 00:00:00 EDT 2014
Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol.
Biochimica et biophysica acta
Küch EM,Vellaramkalayil R,Zhang I,Lehnen D,Brügger B,Sreemmel W,Ehehalt R,Poppelreuther M,Füllekrug J
MA3-914 was used in western blot to study the role in channeling fatty acids to phosphatidyl inositol of three variants of acyl-CoA synthetase-4 that display different subcellular localizations
Sat Feb 01 00:00:00 EST 2014
Targeted expression of anoctamin calcium-activated chloride channels in rod photoreceptor terminals of the rodent retina.
Investigative ophthalmology & visual science
Dauner K,Möbus C,Frings S,Möhrlen F
MA3-914 was used in western blot to examine both rod spherules and cone pedicles for anoctamin 2 expression
Fri May 03 00:00:00 EDT 2013
The membrane potential modulates thrombin-stimulated Ca²⁺ mobilization and platelet aggregation.
Archives of biochemistry and biophysics
Albarrán L,Dionisio N,López E,Salido GM,Rosado JA
MA3-914 was used in immunoprecipitation to study the mechanism underlying the effects of membrane-depolarization on thrombin-stimulated calcium flux and platelet aggregation
Tue Oct 15 00:00:00 EDT 2013
Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity.
PloS one
Groenke S,Larson ED,Alber S,Zhang R,Lamp ST,Ren X,Nakano H,Jordan MC,Karagueuzian HS,Roos KP,Nakano A,Proenza C,Philipson KD,Goldhaber JI
MA3-914 was used in western blot to study the elimination of sinoatrial node pacemaker activity by the complete atrial-specific ablation of NCX1
Tue Aug 05 00:00:00 EDT 2014
Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells.
EMBO molecular medicine
Leanza L,Henry B,Sassi N,Zoratti M,Chandy KG,Gulbins E,Szabò I
MA3-914 was used in western blot to study the ability of inhibitors of mitochondrial Kv1.3 channels to induce Bax/Bak-independent death of cancer cells
Sun Jul 01 00:00:00 EDT 2012
Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia impairs Ca2+ homeostasis.
Proceedings of the National Academy of Sciences of the United States of America
Zanni G,Calì T,Kalscheuer VM,Ottolini D,Barresi S,Lebrun N,Montecchi-Palazzi L,Hu H,Chelly J,Bertini E,Brini M,Carafoli E
MA3-914 was used in immunocytochemistry to study the effects on Ca(2+) homeostasis of a plasma membrane Ca(2+)-ATPase mutation identified in a familiy with X-linked congenital cerebellar ataxia
Tue Sep 04 00:00:00 EDT 2012
Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.
Current medicinal chemistry
Leanza L,Zoratti M,Gulbins E,Szabò I
MA3-914 was used in western blot to study the role of the Kv 1.3 and Kv 1.5 potassium channels in the induction of macrophage apoptosis
Wed May 22 00:00:00 EDT 2013
The development, distribution and density of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells.
The European journal of neuroscience
Chen Q,Mahendrasingam S,Tickle JA,Hackney CM,Furness DN,Fettiplace R
MA3-914 was used in immunohistochemistry to study the localization and function of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells
Wed Aug 01 00:00:00 EDT 2012
Distinct regulation of cytoplasmic calcium signals and cell death pathways by different plasma membrane calcium ATPase isoforms in MDA-MB-231 breast cancer cells.
The Journal of biological chemistry
Curry MC,Luk NA,Kenny PA,Roberts-Thomson SJ,Monteith GR
MA3-914 was used in western blot to study the roles of different plasma membrane calcium ATPase isoforms in cytoplasmic Ca2+ signaling and cell death
Fri Aug 17 00:00:00 EDT 2012
Ca2+-activated Cl− currents are dispensable for olfaction.
Nature neuroscience
Billig GM,Pál B,Fidzinski P,Jentsch TJ
MA3-914 was used in immunohistochemistry to investigate the involvement of calcium-activated chloride channels in olfaction
Wed Jun 01 00:00:00 EDT 2011
FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.
American journal of physiology. Endocrinology and metabolism
Digel M,Staffer S,Ehehalt F,Stremmel W,Ehehalt R,Füllekrug J
MA3-914 was used in western blot to investigate the role of acyl-CoA synthetase fatty acid transport protein-4 in basal and insulin-mediated fatty acid uptake
Tue Nov 01 00:00:00 EDT 2011
Dysregulation of Ca2+ signaling in astrocytes from mice lacking amyloid precursor protein.
American journal of physiology. Cell physiology
Linde CI,Baryshnikov SG,Mazzocco-Spezzia A,Golovina VA
MA3-914 was used in western blot to investigate the role of amyloid-beta precursor protein in astrocytic calcium signaling
Wed Jun 01 00:00:00 EDT 2011
Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cells.
American journal of physiology. Heart and circulatory physiology
Lock JT,Sinkins WG,Schilling WP
MA3-914 was used in western blot to investigate the effect of glutathionylation of the IP3R on calcium homeostasis
Tue Feb 01 00:00:00 EST 2011
Mutations in PMCA2 and hereditary deafness: a molecular analysis of the pump defect.
Cell calcium
Giacomello M,De Mario A,Lopreiato R,Primerano S,Campeol M,Brini M,Carafoli E
MA3-914 was used in western blot to study PMCA2 pump mutant on molecular level
Thu Dec 01 00:00:00 EST 2011
Sodium-calcium exchanger and lipid rafts in pig coronary artery smooth muscle.
Biochimica et biophysica acta
Kuszczak I,Samson SE,Pande J,Shen DQ,Grover AK
MA3-914 was used in western blot to study the association of NCX1 and SERCA2 with one another and with lipid rafts in pig coronary artery smooth muscle
Tue Mar 01 00:00:00 EST 2011
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout.
The Journal of physiology
Louch WE,Hougen K,Mørk HK,Swift F,Aronsen JM,Sjaastad I,Reims HM,Roald B,Andersson KB,Christensen G,Sejersted OM
MA3-914 was used in western blot to examine the effects of sodium accumulation on diastolic function following Serca2 knockout
Mon Feb 01 00:00:00 EST 2010
Upregulation of Na+/Ca2+ exchanger and TRPC6 contributes to abnormal Ca2+ homeostasis in arterial smooth muscle cells from Milan hypertensive rats.
American journal of physiology. Heart and circulatory physiology
Zulian A,Baryshnikov SG,Linde CI,Hamlyn JM,Ferrari P,Golovina VA
MA3-914 was used in western blot to study the role of TRPC6 and NCX1 in a model of hypertension.
Wed Sep 01 00:00:00 EDT 2010
Na(+)-K(+)-ATPase and Ca(2+) clearance proteins in smooth muscle: a functional unit.
American journal of physiology. Heart and circulatory physiology
Pritchard TJ,Bowman PS,Jefferson A,Tosun M,Lynch RM,Paul RJ
MA3-914 was used in western blot to investigate the function of sodium/potassium-ATPase and calcim clearance proteins
Sun Aug 01 00:00:00 EDT 2010
Caloxin 1b3: a novel plasma membrane Ca(2+)-pump isoform 1 selective inhibitor that increases cytosolic Ca(2+) in endothelial cells.
Cell calcium
Szewczyk MM,Pande J,Akolkar G,Grover AK
MA3-914 was used in western blot to investigate the effect of caloxin 1b3 on PMCA1 and calcium homeostasis
Wed Dec 01 00:00:00 EST 2010
An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1.
Biochimica et biophysica acta
Sassi N,De Marchi U,Fioretti B,Biasutto L,Gulbins E,Franciolini F,Szabò I,Zoratti M
MA3-914 was used in western blot to characterize the mitochondrial intermediate-conductance calcium-activated potassium channel mtKCa3.1
Mon Jan 10 00:00:00 EST 2011
Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231.
The Journal of biological chemistry
Grice DM,Vetter I,Faddy HM,Kenny PA,Roberts-Thomson SJ,Monteith GR
MA3-914 was used in western blot to investigate the effect of SPCA1 on IGF1R in MDA-MB-231 cell
Fri Nov 26 00:00:00 EST 2010
Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel.
American journal of physiology. Cell physiology
Sinkins WG,Estacion M,Prasad V,Goel M,Shull GE,Kunze DL,Schilling WP
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Western Blot
Tue Dec 01 00:00:00 EST 2009
Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells.
Cell calcium
De Marchi U,Sassi N,Fioretti B,Catacuzzeno L,Cereghetti GM,Szabò I,Zoratti M
MA3-914 was used in western blot to investigate the intermediate conductance calcium-activated potassium channel(Kca 3.1) in the inner membrane of colon cancer cell mitochondria
Fri May 01 00:00:00 EDT 2009
Muscarinic-induced recruitment of plasma membrane Ca2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions.
The Journal of biological chemistry
Kruger WA,Yun CC,Monteith GR,Poronnik P
MA3-914 was used in Western Blotting to explore the molecular mechanisms that underpin the trafficking of plasma membrane Ca2+-ATPases to the membrane during Ca2+ signalling.
Fri Jan 16 00:00:00 EST 2009
Reduced expression of sarcalumenin and related Ca2+ -regulatory proteins in aged rat skeletal muscle.
Experimental gerontology
O'Connell K,Gannon J,Doran P,Ohlendieck K
MA3-914 was used in western blot to investigate the expression of sarcalumenin and related calcium-regulatory proteins in rodent skeletal muscle during aging
Wed Oct 01 00:00:00 EDT 2008
Internalization of plasma membrane Ca2+-ATPase during Xenopus oocyte maturation.
Developmental biology
El-Jouni W,Haun S,Machaca K
MA3-914 was used in immunocytochemistry and western blot to investigate the mechanisms for plasma membrane calcium-ATPase (PMCA) internalization during oocyte maturation
Mon Dec 01 00:00:00 EST 2008
Internalization of plasma membrane Ca2+-ATPase during Xenopus oocyte maturation.
Developmental biology
El-Jouni W,Haun S,Machaca K
MA3-914 was used in immunocytochemistry and western blot to investigate the mechanisms for plasma membrane calcium-ATPase (PMCA) internalization during oocyte maturation
Mon Dec 01 00:00:00 EST 2008
Functional and immunocytochemical evidence for the expression and localization of the secretory pathway Ca2+-ATPase isoform 1 (SPCA1) in cerebellum relative to other Ca2+ pumps.
Journal of neurochemistry
Sepúlveda MR,Berrocal M,Marcos D,Wuytack F,Mata AM
MA3-914 was used in immunohistochemistry to study the expression and localization of the SPCA1 Ca(2+)-ATPase in pig cerebellum and its potential role in secretory pathway Ca(2+) metabolism
Thu Nov 01 00:00:00 EDT 2007
Protein stability and the evolution of the cell membrane.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
Mas-Oliva J,Delgado-Coello B
MA3-914 was used in western blot to study the role of the cell membrane in protein stability
Tue Oct 02 00:00:00 EDT 2007
Regulation of plasma membrane Ca2+-ATPase in human platelets by calpain.
Platelets
Brown CS,Dean WL
MA3-914 was used in western blot to study the regulation of human platelet plasma membrane Ca2+-ATPase by calpain
Tue May 01 00:00:00 EDT 2007
Spatiotemporal regulation of ATP and Ca2+ dynamics in vertebrate rod and cone ribbon synapses.
Molecular vision
Johnson JE,Perkins GA,Giddabasappa A,Chaney S,Xiao W,White AD,Brown JM,Waggoner J,Ellisman MH,Fox DA
Published figure using PMCA ATPase monoclonal antibody (Product # MA3-914) in Immunofluorescence
Fri Jun 15 00:00:00 EDT 2007
Impaired megakaryocytopoiesis in type 2B von Willebrand disease with severe thrombocytopenia.
Blood
Nurden P,Debili N,Vainchenker W,Bobe R,Bredoux R,Corvazier E,Combrie R,Fressinaud E,Meyer D,Nurden AT,Enouf J
MA3-914 was used in western blot to report on a family with type 2B von Willebrand disease and displaying abnormal platelet production
Sun Oct 15 00:00:00 EDT 2006
Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.
American journal of physiology. Cell physiology
Liu L,Ishida Y,Okunade G,Shull GE,Paul RJ
MA3-914 was used in western blot to study the role of membrane Ca2+-ATPase in contraction-relaxation processes of the bladder
Sat Apr 01 00:00:00 EST 2006
Plasma membrane calcium pumps in mouse olfactory sensory neurons.
Chemical senses
Weeraratne SD,Valentine M,Cusick M,Delay R,Van Houten JL
MA3-914 was used in immunocytochemistry to investigate specific plasma membrane calcium pumps in mouse olfactory sensory neurons.
Sun Oct 01 00:00:00 EDT 2006
Sarco/endoplasmic reticulum Ca2+ATPase type 3 isoforms (SERCA3b and SERCA3f): distinct roles in cell adhesion and ER stress.
Biochemical and biophysical research communications
Chaâbane C,Corvazier E,Bredoux R,Dally S,Raïes A,Villemain A,Dupuy E,Enouf J,Bobe R
MA3-914 was used in western blot to study the distinct roles of SERCA3a and SERCA3f in cellular adhesion and endoplasmic reticulum stress
Fri Jul 14 00:00:00 EDT 2006
Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory.
The Journal of biological chemistry
Li XF,Kiedrowski L,Tremblay F,Fernandez FR,Perizzolo M,Winkfein RJ,Turner RW,Bains JS,Rancourt DE,Lytton J
MA3-914 was used in western blot to investigate the role of the potassium-dependent sodium/calcium-exchanger 2 in neuronal calcium control.
Fri Mar 10 00:00:00 EST 2006
Adenovirally delivered shRNA strongly inhibits Na+-Ca2+ exchanger expression but does not prevent contraction of neonatal cardiomyocytes.
Journal of molecular and cellular cardiology
Hurtado C,Ander BP,Maddaford TG,Lukas A,Hryshko LV,Pierce GN
MA3-914 was used in western blot to study the effect of NCX1 inhibition on the contraction of neonatal cardiomyocytes
Fri Apr 01 00:00:00 EST 2005
Antisense-mediated Inhibition of the plasma membrane calcium-ATPase suppresses proliferation of MCF-7 cells.
The Journal of biological chemistry
Lee WJ,Robinson JA,Holman NA,McCall MN,Roberts-Thomson SJ,Monteith GR
MA3-914 was used in western blot to demonstrate the role of plasma membrane calcium ATPase in human breast cancer MCF-7 cell proliferation.
Fri Jul 22 00:00:00 EDT 2005
Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice.
The Journal of biological chemistry
Luo X,Shin DM,Wang X,Konieczny SF,Muallem S
MA3-914 was used in western blot to investigate the role of PMCA during the aberrant localization of intracellular organelles caused by the lack of Mist1.
Fri Apr 01 00:00:00 EST 2005
Inhibitory interaction of the 14-3-3{epsilon} protein with isoform 4 of the plasma membrane Ca(2+)-ATPase pump.
The Journal of biological chemistry
Rimessi A,Coletto L,Pinton P,Rizzuto R,Brini M,Carafoli E
MA3-914 was used in immunoprecipitation to study the inhibitory interaction of 14-3-3epsilon with plasma membrane Ca(2+) ATPase isoform 4
Fri Nov 04 00:00:00 EST 2005
Bcr (breakpoint cluster region) protein binds to PDZ-domains of scaffold protein PDZK1 and vesicle coat protein Mint3.
Journal of cell science
Malmberg EK,Andersson CX,Gentzsch M,Chen JH,Mengos A,Cui L,Hansson GC,Riordan JR
MA3-914 was used in immunocytochemistry to study the binding of Bcr to the apical PDZK1 protein and to the Golgi-localized Mint3.
Mon Nov 01 00:00:00 EST 2004
Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum).
The Journal of comparative neurology
Krizaj D,Liu X,Copenhagen DR
MA3-914 was used in immunohistochemistry to investigate how cytoplasmic free calcium in neurons from the salamander retina is regulated
Mon Aug 02 00:00:00 EDT 2004
Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.
The Journal of biological chemistry
Okunade GW,Miller ML,Pyne GJ,Sutliff RL,O'Connor KT,Neumann JC,Andringa A,Miller DA,Prasad V,Doetschman T,Paul RJ,Shull GE
MA3-914 was used in western blot to show the role of plasma membrane calcium ATPase in the principle piece of the sperm tail in hyperactivated sperm motility and male fertility.
Fri Aug 06 00:00:00 EDT 2004
Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities.
The Journal of cell biology
Shin DM,Dehoff M,Luo X,Kang SH,Tu J,Nayak SK,Ross EM,Worley PF,Muallem S
MA3-914 was used in western blot to investigate the functions of Homer proteins.
Mon Jul 21 00:00:00 EDT 2003
Basic fibroblast growth factor (bFGF) regulation of the plasma membrane calcium ATPase (PMCA) as part of an anti-apoptotic mechanism of action.
Biochemical pharmacology
Peluso JJ
MA3-914 was used in western blot to study the role of basic fibroblast growth factor in cell viability
Wed Oct 15 00:00:00 EDT 2003
Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.
Cell calcium
Reuter H,Henderson SA,Han T,Mottino GA,Frank JS,Ross RS,Goldhaber JI,Philipson KD
MA3-914 was used in western blot to investigate the effect of sodium-calcium exchange on cardiac excitation-contraction coupling
Tue Jul 01 00:00:00 EDT 2003
Localization of alkaline phosphatase and Ca2+-ATPase in the cat placenta.
Placenta
Champion EE,Glazier JD,Greenwood SL,Mann SJ,Rawlings JM,Sibley CP,Jones CJ
MA3-914 was used in immunohistochemistry to show the localization of PMCA in the cat placenta
Thu May 01 00:00:00 EDT 2003
Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude.
Circulation research
Yarbrough TL,Lu T,Lee HC,Shibata EF
MA3-914 was used in western blot to locate cardiac sodium channels in caveolar membrane domains
Fri Mar 08 00:00:00 EST 2002
Ca2+-dependent protein kinase--a modulation of the plasma membrane Ca2+-ATPase in parotid acinar cells.
The Journal of biological chemistry
Bruce JI,Yule DI,Shuttleworth TJ
MA3-914 was used in immunoprecipitation to investigate how cAMP regulates calcium clearance pathways in parotid acinar cells.
Fri Dec 13 00:00:00 EST 2002
nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?
American journal of physiology. Gastrointestinal and liver physiology
Daniel EE,Jury J,Wang YF
MA3-914 was used in immunohistochemistry to investigate the colocalization of nNOS with Cav-1 and calcium-handling proteins
Mon Oct 01 00:00:00 EDT 2001
Are B-type Ca2+ channels of cardiac myocytes akin to the passive ion channel in the plasma membrane Ca2+ pump?
The Journal of membrane biology
Antoine S,Pinet C,Coulombe A
MA3-914 was used in blocking or activating experiment to study the relationship of the cardiac B-type Ca(2+) channel to the plasma membrane Ca(2+)-ATPase pump
Mon Jan 01 00:00:00 EST 2001
Localization of sequences within the C-terminal domain of the cystic fibrosis transmembrane conductance regulator which impact maturation and stability.
The Journal of biological chemistry
Gentzsch M,Riordan JR
MA3-914 was used in immunocytochemistry to identify the gene segments in the cystic fibrosis transmembrane conductance regulator important for its assembly and stability.
Fri Jan 12 00:00:00 EST 2001
Plasma membrane Ca(2+)-ATPase associates with the cytoskeleton in activated platelets through a PDZ-binding domain.
The Journal of biological chemistry
Zabe M,Dean WL
MA3-914 was used in western blot to study the association of plasma membrane calcium-ATPase with the cytoskeleton.
Fri May 04 00:00:00 EDT 2001
Tyrosine phosphorylation of human platelet plasma membrane Ca(2+)-ATPase in hypertension.
Hypertension (Dallas, Tex. : 1979)
Blankenship KA,Dawson CB,Aronoff GR,Dean WL
MA3-914 was used in western blot to study the possible effects of tyrosine phosphorylation of PMCA in hypertensive patients on inhibition of the calcium pump in hypertension
Sat Jan 01 00:00:00 EST 2000
Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.
The Journal of biological chemistry
Rosado JA,Sage SO
MA3-914 was used in western blot to investigate the regulation of Ca2+-ATPase-mediated calcium extrusion by small GTPases and PI3K.
Fri Jun 30 00:00:00 EDT 2000
Molecular dissection of Ca2+ efflux in immortalized proximal tubule cells.
The Journal of general physiology
White KE,Gesek FA,Nesbitt T,Drezner MK,Friedman PA
MA3-914 was used in western blot to study the extrusion mechanism of the calcium efflux in proximal tubule cells
Sat Feb 01 00:00:00 EST 1997
Regulation of platelet plasma membrane Ca2+-ATPase by cAMP-dependent and tyrosine phosphorylation.
The Journal of biological chemistry
Dean WL,Chen D,Brandt PC,Vanaman TC
MA3-914 was used in western blot to study the tyrosine phosphorylation of PMCA in human platelets
Fri Jun 13 00:00:00 EDT 1997
Expression of the plasma membrane Ca2+-ATPase in myogenic cells.
The Journal of biological chemistry
Hammes A,Oberdorf-Maass S,Jenatschke S,Pelzer T,Maass A,Gollnick F,Meyer R,Afflerbach J,Neyses L
MA3-914 was used in western blot to detect the expression of the plasma membrane calcium-ATPase (PMCA) in myogenic cells
Fri Nov 29 00:00:00 EST 1996
Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.
Proceedings of the National Academy of Sciences of the United States of America
Schnitzer JE,Oh P,Jacobson BS,Dvorak AM
MA3-914 was used in western blot to perform structural and functional analysis on purified caveolae from luminal plasmalemma of rat lung endothelium
Tue Feb 28 00:00:00 EST 1995
Distribution of plasma membrane Ca(2+)-ATPase and inositol 1,4,5-trisphosphate receptor in human platelet membranes.
Cell calcium
Dean WL,Quinton TM
MA3-914 was used in western blot to investigate the distribution of plasma membrane calcium-ATPase and inositol 1,4,5-trisphosphate receptor in human platelet membranes
Sun Jan 01 00:00:00 EST 1995
Localization and identification of Ca2+ATPases in highly purified human platelet plasma and intracellular membranes. Evidence that the monoclonal antibody PL/IM 430 recognizes the SERCA 3 Ca2+ATPase in human platelets.
The Biochemical journal
Bokkala S,el-Daher SS,Kakkar VV,Wuytack F,Authi KS
MA3-914 was used in western blot to identify and locate calcium-ATPases in human platelet plasma and intracellular membranes
Wed Mar 15 00:00:00 EST 1995
Thapsigargin-sensitive Ca(2+)-ATPases account for Ca2+ uptake to inositol 1,4,5-trisphosphate-sensitive and caffeine-sensitive Ca2+ stores in adrenal chromaffin cells.
The Biochemical journal
Poulsen JC,Caspersen C,Mathiasen D,East JM,Tunwell RE,Lai FA,Maeda N,Mikoshiba K,Treiman M
MA3-914 was used in western blot to study the effect of thapsigargin-sensitive calcium-ATPases on calcium homeostasis in adrenal chromaffin cells
Mon May 01 00:00:00 EDT 1995
Use of expression mutants and monoclonal antibodies to map the erythrocyte Ca2+ pump.
The Journal of biological chemistry
Adamo HP,Caride AJ,Penniston JT
MA3-914 was used in western blot to investigate the human erythrocyte caclium pump through the use of mutants and monoclonal antibodies
Wed Jul 15 00:00:00 EDT 1992
