Product References
Impact of a SLC24A5 variant on the retinal pigment epithelium of a Japanese patient with oculocutaneous albinism type 6.
Pigment cell & melanoma research
Saito T,Okamura K,Kosaki R,Wakamatsu K,Ito S,Nakajima O,Yamashita H,Hozumi Y,Suzuki T
MA5-13232 was used in Immunohistochemistry (Paraffin), Western Blot to reveal a significant pigment loss in the retinal pigment epithelium (RPE) but not in the choroid.
Tue Mar 01 00:00:00 EST 2022
Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity.
EMBO reports
Matafora V,Farris F,Restuccia U,Tamburri S,Martano G,Bernardelli C,Sofia A,Pisati F,Casagrande F,Lazzari L,Marsoni S,Bonoldi E,Bachi A
MA5-13232 was used in Western Blot, Immunocytochemistry to demonstrate that BACE inhibition affects cell proliferation and increases drug sensitivity, highlighting the importance of amyloids for melanoma survival, and the use of beta-secretase inhibitors as potential therapeutic approach for metastatic melanoma.
Thu Sep 03 00:00:00 EDT 2020
Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity.
EMBO reports
Matafora V,Farris F,Restuccia U,Tamburri S,Martano G,Bernardelli C,Sofia A,Pisati F,Casagrande F,Lazzari L,Marsoni S,Bonoldi E,Bachi A
MA5-13232 was used in Western Blot, Immunocytochemistry to demonstrate that BACE inhibition affects cell proliferation and increases drug sensitivity, highlighting the importance of amyloids for melanoma survival, and the use of beta-secretase inhibitors as potential therapeutic approach for metastatic melanoma.
Thu Sep 03 00:00:00 EDT 2020
Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity.
EMBO reports
Matafora V,Farris F,Restuccia U,Tamburri S,Martano G,Bernardelli C,Sofia A,Pisati F,Casagrande F,Lazzari L,Marsoni S,Bonoldi E,Bachi A
MA5-13232 was used in Western Blot, Immunocytochemistry to demonstrate that BACE inhibition affects cell proliferation and increases drug sensitivity, highlighting the importance of amyloids for melanoma survival, and the use of beta-secretase inhibitors as potential therapeutic approach for metastatic melanoma.
Thu Sep 03 00:00:00 EDT 2020
Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity.
EMBO reports
Matafora V,Farris F,Restuccia U,Tamburri S,Martano G,Bernardelli C,Sofia A,Pisati F,Casagrande F,Lazzari L,Marsoni S,Bonoldi E,Bachi A
MA5-13232 was used in Western Blot, Immunocytochemistry to demonstrate that BACE inhibition affects cell proliferation and increases drug sensitivity, highlighting the importance of amyloids for melanoma survival, and the use of beta-secretase inhibitors as potential therapeutic approach for metastatic melanoma.
Thu Sep 03 00:00:00 EDT 2020
Mitochondrial NCKX5 regulates melanosomal biogenesis and pigment production.
Journal of cell science
Zhang Z,Gong J,Sviderskaya EV,Wei A,Li W
MA5-13232 was used in Immunocytochemistry-immunoflourescence to study the pathogenesis of Oculocutaneous albinism (OCA) type 6.
Mon Jul 15 00:00:00 EDT 2019
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.
Molecular vision
Samuel W,Jaworski C,Postnikova OA,Kutty RK,Duncan T,Tan LX,Poliakov E,Lakkaraju A,Redmond TM
MA513232 was used in immunocytochemistry to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells
Fri Feb 09 00:00:00 EST 2018
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.
Molecular vision
Samuel W,Jaworski C,Postnikova OA,Kutty RK,Duncan T,Tan LX,Poliakov E,Lakkaraju A,Redmond TM
MA513232 was used in immunocytochemistry to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells
Fri Feb 09 00:00:00 EST 2018
Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes.
Oncotarget
Ling Y,Gong Q,Xiong X,Sun L,Zhao W,Zhu W,Lu Y
MA5-13232 was used in Immunocytochemistry to evaluate the effects of madecassoside on oxidative stress in human melanocytes and its mechanism of action.
Tue Aug 01 00:00:00 EDT 2017
BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers.
The Journal of cell biology
Dennis MK,Delevoye C,Acosta-Ruiz A,Hurbain I,Romao M,Hesketh GG,Goff PS,Sviderskaya EV,Bennett DC,Luzio JP,Galli T,Owen DJ,Raposo G,Marks MS
MA5-13232 was used in immunocytochemistry to propose that VAMP7 mediates fusion of BLOC-1-dependent transport carriers with melanosomes
Mon Aug 01 00:00:00 EDT 2016
NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline.
JCI insight
Osterburg AR,Nelson RL,Yaniv BZ,Foot R,Donica WR,Nashu MA,Liu H,Wikenheiser-Brokamp KA,Moss J,Gupta N,McCormack FX,Borchers MT
MA513232 was used in immunohistochemistry - frozen section to investigate the role of natural killer cells to lymphangioleiomyomatosis pathogenesis
Thu Oct 06 00:00:00 EDT 2016
BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery.
The Journal of cell biology
Dennis MK,Mantegazza AR,Snir OL,Tenza D,Acosta-Ruiz A,Delevoye C,Zorger R,Sitaram A,de Jesus-Rojas W,Ravichandran K,Rux J,Sviderskaya EV,Bennett DC,Raposo G,Marks MS,Setty SR
MA5-13232 was used in flow cytometry to investigate the role of BLOC-2 in endosomal tubular transport in melanosomes
Mon May 25 00:00:00 EDT 2015
A challenging case of ocular melanoma.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Costache M,Dumitru AV,Pătraşcu OM,Popa-Cherecheanu DA,Bădilă P,Miu JC,Procop A,Popa M,Tampa MŞ,Sajin M,Simionescu O,Cîrstoiu MM
MA5-13232 was used in immunohistochemistry to present a case of highly aggressive ocular melanoma
Tue May 10 00:00:00 EDT 2016
ASPL-TFE3 translocation in vulvovaginal alveolar soft part sarcoma.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Jabbour MN,Seoud M,Al-Ahmadie H,Abdul-Karim FW,Zaatari GS
MA5-13232 was used in immunohistochemistry to report on a case of vulvovaginal alveolar soft part sarcoma
Thu May 01 00:00:00 EDT 2014
Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient.
Molecular vision
Abad S,Wieërs G,Colau D,Wildmann C,Delair E,Dhote R,Brézin AP,Kawakami Y,Coulie PG,van der Bruggen P
MA5-13232 was used in western blot to identify antigens recognized by autoreactive CD4 T lymphocytes isolated from a Vogt-Koyanagi-Harada patient who did not express HLA-DRB1*04:05
Tue Sep 30 00:00:00 EDT 2014
Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.
Cancer research
Duong T,Proulx ST,Luciani P,Leroux JC,Detmar M,Koopman P,Francois M
MA5-13232 was used in immunohistochemistry to study the role of SOX18 function function in tumor lymphangiogenesis and metastasis of melanoma in mice
Fri Jun 15 00:00:00 EDT 2012
Targeting BRAFV600E in an inducible murine model of melanoma.
The American journal of pathology
Hooijkaas AI,Gadiot J,van der Valk M,Mooi WJ,Blank CU
MA5-13232 was used in immunohistochemistry to study the effects of targeting BRAF(V600E) on melanoma growth in an inducible murine model
Sat Sep 01 00:00:00 EDT 2012
Cellular and clinical report of new Griscelli syndrome type III cases.
Pigment cell & melanoma research
Westbroek W,Klar A,Cullinane AR,Ziegler SG,Hurvitz H,Ganem A,Wilson K,Dorward H,Huizing M,Tamimi H,Vainshtein I,Berkun Y,Lavie M,Gahl WA,Anikster Y
MA5-13232 was used in immunocytochemistry to report on new cases of Griscelli syndrome type III
Sun Jan 01 00:00:00 EST 2012
Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.
Molecular biology of the cell
Sitaram A,Dennis MK,Chaudhuri R,De Jesus-Rojas W,Tenza D,Setty SR,Wood CS,Sviderskaya EV,Bennett DC,Raposo G,Bonifacino JS,Marks MS
MA5-13232 was used in immunocytochemistry to study the delivery of OCA2 to melanosomes and the distinct roles played by AP-1 and AP-3
Wed Aug 01 00:00:00 EDT 2012
Effect of PUVA therapy on melanocytes and keratinocytes in non-segmental vitiligo: histopathological, immuno-histochemical and ultrastructural study.
Photodermatology, photoimmunology & photomedicine
Anbar TS,El-Sawy AE,Attia SK,Barakat MT,Moftah NH,El-Ammawy TS,Abdel-Rahman AT,El-Tonsy MH
MA5-13232 was used in immunohistochemistry to study the effects of PUVA treatment on melanocytes and keratinocytes from patients with non-segmental vitiligo
Wed Feb 01 00:00:00 EST 2012
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
Diagnostic pathology
Yin WH,Li J,Chan JK
MA5-13232 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
Thu Apr 12 00:00:00 EDT 2012
Cardiac Epithelioid PEComa: Report of Two Cases and Review of the Literature.
Case reports in medicine
Niu H,Wang FW,Zhang PJ,Bing Z
MA5-13232 was used in immunohistochemistry - paraffin section to present two cases of epithelioid PEComas
Fri Sep 14 00:00:00 EDT 2012
Endoscopic ultrasound-guided fine-needle aspiration of intrathoracic and intra-abdominal spindle cell and mesenchymal lesions.
Cancer cytopathology
Bean SM,Baker A,Eloubeidi M,Eltoum I,Jhala N,Crowe R,Jhala D,Chhieng DC
MA5-13232 was used in immunocytochemistry to confirm the diagnostic value of endoscopic ultrasound-guided fine-needle aspiration
Fri Feb 25 00:00:00 EST 2011
Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Clay MR,Gibson P,Lowell J,Cooper K
MA5-13232 was used in immunohistochemistry to report a clinical case of microscopic lymphangioleiomyomatosis perivascular epithelioid cell neoplasm in uterus
Sat Jan 01 00:00:00 EST 2011
Primary myoepithelial carcinoma of the larynx: case report and review of the literature.
Pathology, research and practice
Yu G,Qu G,Kong L,Pan X,Wang W,Lv J
MA5-13232 was used in immunohistochemistry to report on a case of primary myoepithelial carcinoma of the larynx
Tue Feb 15 00:00:00 EST 2011
Proprotein convertases process Pmel17 during secretion.
The Journal of biological chemistry
Leonhardt RM,Vigneron N,Rahner C,Cresswell P
MA5-13232 was used in immunocytochemistry and western blot to study Pmel17 processing in melanocytes
Fri Mar 18 00:00:00 EDT 2011
Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic.
PLoS genetics
Watt B,Tenza D,Lemmon MA,Kerje S,Raposo G,Andersson L,Marks MS
MA5-13232 was used in western blot to investigate the role of PMEL mutations in physiological and pathological amyloid fibril formation
Thu Sep 01 00:00:00 EDT 2011
Pulmonary meningothelial-like nodules: new insights into a common but poorly understood entity.
The American journal of surgical pathology
Mukhopadhyay S,El-Zammar OA,Katzenstein AL
MA5-13232 was used in immunohistochemistry to study pulmonary meningothelial-like nodules
Wed Apr 01 00:00:00 EDT 2009
Clinical and cellular characterisation of Hermansky-Pudlak syndrome type 6.
Journal of medical genetics
Huizing M,Pederson B,Hess RA,Griffin A,Helip-Wooley A,Westbroek W,Dorward H,O'Brien KJ,Golas G,Tsilou E,White JG,Gahl WA
MA5-13232 was used in immunocytochemistry to study the clinical and cellular characteristics of Hermansky-Pudlak syndrome subtype 6
Tue Dec 01 00:00:00 EST 2009
Patterns of repigmentation in two cases of hypopigmented type of vitiligo.
Photodermatology, photoimmunology & photomedicine
Anbar TS,El-Sawy AE,Attia SK,Moftah NH,El-Tonsy MH
MA5-13232 was used in immunohistochemistry to study patterns of repigmentation in two cases of hypopigmented type of vitiligo
Mon Jun 01 00:00:00 EDT 2009
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
Nature
Setty SR,Tenza D,Sviderskaya EV,Bennett DC,Raposo G,Marks MS
MA5-13232 was used in western blot to investigate the role of cell-specific ATP7A transport in copper-dependent tyrosinase activity of melanosomes
Thu Aug 28 00:00:00 EDT 2008
Rab7 regulates maturation of melanosomal matrix protein gp100/Pmel17/Silv.
The Journal of investigative dermatology
Kawakami A,Sakane F,Imai S,Yasuda S,Kai M,Kanoh H,Jin HY,Hirosaki K,Yamashita T,Fisher DE,Jimbow K
MA5-13232 was used in western blot to study the regulation of the melanosomal matrix protein gp100 by Rab7
Tue Jan 01 00:00:00 EST 2008
Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.
Journal of cellular physiology
Roberts DW,Newton RA,Leonard JH,Sturm RA
MA5-13232 was used in western blot to study the behavior and functional abilities of melanocytes expressing MC1R red hair color variants
Thu May 01 00:00:00 EDT 2008
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome.
Molecular genetics and metabolism
Westbroek W,Tuchman M,Tinloy B,De Wever O,Vilboux T,Hertz JM,Hasle H,Heilmann C,Helip-Wooley A,Kleta R,Gahl WA
MA5-13232 was used in immunocytochemistry to investigate the role of Rab27A specific mutation in Griscelli syndrome
Sun Jun 01 00:00:00 EDT 2008
Vacuolar-type H(+)-ATPase with the a3 isoform is the proton pump on premature melanosomes.
Cell and tissue research
Tabata H,Kawamura N,Sun-Wada GH,Wada Y
MA5-13232 was used in immunohistochemistry to identify the proton pump on immature melanosomes as the vacuolar H(+)-ATPase a3 isoform
Sun Jun 01 00:00:00 EDT 2008
Epithelioid smooth muscle tumors of the uterus do not express CD1a: a potential immunohistochemical adjunct in their distinction from uterine perivascular epithelioid cell tumors.
Annals of diagnostic pathology
Fadare O,Liang SX
MA5-13232 was used in immunohistochemistry to investigate the level of CD1a in uterine epithelioid smooth muscle tumors
Mon Dec 01 00:00:00 EST 2008
Cutaneous metastases of malignant melanoma--how difficult can it be?
Romanian journal of internal medicine = Revue roumaine de medecine interne
Zurac S,Andrei R,Petsakos G,Nichita L,Bastian A,Micu G,Gramadă E,Popp C,Stăniceanu F,Petrescu S,Negroiu G,Giurcăneanu D,Chiţu V
MA5-13232 was used in immunohistochemistry to investigate the differentiating features between primary melanoma and its cutaneous metastasis
Fri Jun 26 00:00:00 EDT 2009
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhang JG,Eguchi J,Kruse CA,Gomez GG,Fakhrai H,Schroter S,Ma W,Hoa N,Minev B,Delgado C,Wepsic HT,Okada H,Jadus MR
MA5-13232 was used in flow cytometry to examine the allogenic glioma cells for the generation of therapeutic vaccines or cellular therapy
Mon Jan 15 00:00:00 EST 2007
Cellular defects in Chediak-Higashi syndrome correlate with the molecular genotype and clinical phenotype.
The Journal of investigative dermatology
Westbroek W,Adams D,Huizing M,Koshoffer A,Dorward H,Tinloy B,Parkes J,Helip-Wooley A,Kleta R,Tsilou E,Duvernay P,Digre KB,Creel DJ,White JG,Boissy RE,Gahl WA
MA5-13232 was used in immunohistochemistry to study the correlation between cellular defects, genotype and clinical phenotype in Chediak-Higashi syndrome
Thu Nov 01 00:00:00 EDT 2007
Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5.
The Journal of investigative dermatology
Helip-Wooley A,Westbroek W,Dorward HM,Koshoffer A,Huizing M,Boissy RE,Gahl WA
MA5-13232 was used in immunocytochemistry to study the trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5 melanocytes
Fri Jun 01 00:00:00 EDT 2007
Characterization of t(6;11)(p21;q12) in a renal-cell carcinoma of an adult patient.
Genes, chromosomes & cancer
Pecciarini L,Cangi MG,Lo Cunsolo C,Macri' E,Dal Cin E,Martignoni G,Doglioni C
MA5-13232 was used in immunohistochemistry to report a clinical case of t(6;11)(p21;q12) renal-cell carcinoma
Tue May 01 00:00:00 EDT 2007
Melanosis in a Holstein heifer.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
Oruç E
MA5-13232 was used in immunohistochemistry to investigate histological features in a Holstein heifer with melanosis
Thu Nov 01 00:00:00 EDT 2007
Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation.
Melanoma research
Wankowicz-Kalinska A,Mailliard RB,Olson K,Graham F,Edington H,Kirkwood JM,Martinek S,Das PK,Storkus WJ
MA5-13232 was used in immunohistochemistry to investigat specific CD8+ tissue-infiltrating T cells in a patient with melanoma
Sat Apr 01 00:00:00 EST 2006
Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules.
Journal of immunology (Baltimore, Md. : 1950)
Ramakrishna V,Treml JF,Vitale L,Connolly JE,O'Neill T,Smith PA,Jones CL,He LZ,Goldstein J,Wallace PK,Keler T,Endres MJ
MA5-13232 was used in blocking or activating experiment to study the T cell immune response against melanoma elicited through conjugation of melanoma antigen with mannose receptor antibody
Mon Mar 01 00:00:00 EST 2004
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis.
The Journal of cell biology
Berson JF,Theos AC,Harper DC,Tenza D,Raposo G,Marks MS
MA5-13232 was used in immunocytochemistry to investigate the role of proprotein convertase cleavage in melanosome biogenesis
Mon May 12 00:00:00 EDT 2003
