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FIGURE: 1 / 1
PODXL Antibody (BS-20488R) in WB
Lane 1: Mouse Kidney lysates; Lane 2: Mouse Heart lysates probed with PODXL Polyclonal Antibody, Unconjugated (bs-20488R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C.
Product Details
BS-20488R
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse PODXL, amino acids 351-450.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC138240; PC; PCLP antibody; PCLP1 antibody; PODLX2; Podocalyxin; Podocalyxin-like protein 1; podolyxin
Gene Aliases: AW121214; Ly102; PC; PCLP-1; Pclp1; podocalyxin; Podxl
UniProt ID: (Rat) Q9WTQ2, (Mouse) Q9R0M4
Entrez Gene ID: (Rat) 192181, (Mouse) 27205
glomerular filtration
cell adhesion
negative regulation of cell adhesion
cell migration
negative regulation of cell-cell adhesion
positive regulation of cell migration
regulation of microvillus assembly
positive regulation of cell-cell adhesion mediated by integrin
leukocyte migration
glomerular visceral epithelial cell development
epithelial tube formation
regulation of cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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