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Invitrogen
POLD1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
POLD1 Antibody (PA5-83823)
Relative expression in different tissues in IHC: Detection of differential expression levels of POLD1 demonstrates antibody specificity. Immunohistochemical analysis of POLD1 using anti-POLD1 Polyclonal Antibody (Product #PA5-83823), shows significant staining of POLD1 in lymph node and shows minimal or weak staining in liver tissues. The relative expression levels of POLD1 within each tissue is shown usin... View More
Product Details
PA5-83823
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human POLD1. Recombinant protein control fragment (Product #RP-89465).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790975
Product Specific Information
Immunogen sequence: YALRLKEKAT QCQLEADVLW SDVVSHPPEG PWQRIAPLRV LSFDIECAGR KGIFPEPERD PVIQICSLGL RWGEPEPFLR LALTLRPCAP ILGAKVQSYE KEEDLLQAWS TFIRIMDPD
Target Information
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exodeoxyribonuclease; CDC2 homolog; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; POL D; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D
Gene Aliases: CDC2; CRCS10; MDPL; POLD; POLD1
UniProt ID: (Human) P28340
Entrez Gene ID: (Human) 5424
telomere maintenance via recombination
telomere maintenance
DNA synthesis involved in DNA repair
DNA replication
DNA strand elongation involved in DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair, gap-filling
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
response to UV
translesion synthesis
nucleotide-excision repair, DNA incision
cellular response to UV
DNA damage response, detection of DNA damage
DNA replication proofreading
fatty acid homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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