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Product Details
PA5-19304
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (AQSLVQGDYGALQSN) corresponding to the internal amino acids of POU3F2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10978158
Product Specific Information
This antibody is predicted to react with bovine and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7-Oct; Brain-2; brain-2 class III POU-domain protein; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2; protein Brn-2
Gene Aliases: 9430075J19Rik; A230098E07Rik; Brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POU3F2; POUF3
UniProt ID: (Human) Q14960, (Mouse) P31360
Entrez Gene ID: (Human) 5454, (Mouse) 18992, (Rat) 29588
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
DNA binding
sequence-specific DNA binding
HMG box domain binding
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
epidermis development
negative regulation of gene expression
astrocyte development
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
hypothalamus cell differentiation
neurohypophysis development
myelination in peripheral nervous system
neuron differentiation
positive regulation of multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
regulation of axonogenesis
cellular response to organic substance
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Schwann cell development
regulation of cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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