Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
MA5-17153
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6H12
Immunogen
Purified recombinant fragment of human POU3F2 (amino acids: 214-362) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538624
Product Specific Information
MA5-17153 targets POU3F2 in indirect ELISA and WB applications and shows reactivity with Human samples.
The MA5-17153 immunogen is purified recombinant fragment of human POU3F2 (amino acids: 214-362) expressed in E. Coli.
MA5-17153 detects POU3F2 which has a predicted molecular weight of approximately 46.9kDa.
Target Information
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 7-Oct; Brain-2; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2
Gene Aliases: brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POU3F2; POUF3
UniProt ID: (Human) Q14960
Entrez Gene ID: (Human) 5454
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
epidermis development
negative regulation of gene expression
astrocyte development
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
hypothalamus cell differentiation
neurohypophysis development
myelination in peripheral nervous system
neuron differentiation
positive regulation of multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
regulation of axonogenesis
cellular response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support