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PPAPDC2 Antibody (PA5-53722) in WB
Western blot analysis of PPAPDC2 in control (vector only transfected HEK293T lysate) and PPAPDC2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a PPAPDC2 Polyclonal Antibody (Product # PA5-53722).
Product Details
PA5-53722
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPAPDC2. Recombinant protein control fragment (Product #RP-91123).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645804
Product Specific Information
Immunogen sequence: PAHNQMDMFV TLSVDKYSFP SGHATRAALM SR
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 94%.
Target Information
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ46512; FLJ90191; Lipid phosphatase-related protein-B; LPRP-B; MGC15483; PA-PSP; phosphatidic acid phosphatase type 2 domain containing 2; Phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; polyisoprenoid diphosphate phosphatase type 1; Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6; PPAP2 domain-containing protein 2; Presqualene diphosphate phosphatase; RP11-6J24.2; Type 1 polyisoprenoid diphosphate phosphatase
Gene Aliases: bA6J24.6; PDP1; PLPP6; PPAPDC2; PSDP
UniProt ID: (Human) Q8IY26
Entrez Gene ID: (Human) 403313
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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