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Product Details
H00063978-M01
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
4F10
Immunogen
A synthetic peptide corresponding to human PRDM14
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DSHVRRSHKE DDC
Target Information
PRDM14 encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PR domain containing 14; PR domain containing 14-like; PR domain zinc finger protein 14; PR domain-containing 14; PR domain-containing protein 14
Gene Aliases: PFM11; PRDM14
UniProt ID: (Human) Q9GZV8
Entrez Gene ID: (Rat) 100365184, (Human) 63978
cell morphogenesis
cell fate specification
inner cell mass cell fate commitment
germ cell development
fertilization
regulation of gene expression
germ-line stem cell population maintenance
histone H3-R26 methylation
regulation of gene expression, epigenetic
negative regulation of fibroblast growth factor receptor signaling pathway
regulation of DNA methylation
homeostasis of number of cells within a tissue
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
embryo implantation
somatic stem cell population maintenance
inactivation of paternal X chromosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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