Proteintech

PRDX1 Polyclonal Antibody

View all (13) PRDX1 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (25)

PRDX1 Antibody in Immunocytochemistry (ICC/IF)

PRDX1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 25

PRDX1 Antibody (15816-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using PRDX1 antibody (Product # 15816-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

PRDX1 Antibody in Immunocytochemistry (ICC/IF)

PRDX1 Antibody in Immunocytochemistry (ICC/IF)

PRDX1 Antibody in Immunocytochemistry (ICC/IF)

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Western Blot (WB)

PRDX1 Antibody in Flow Cytometry (Flow)

PRDX1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

PRDX1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using PRDX1 antibody (Product # 15816-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

PRDX1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of RAW 264.7 cells using 15816-1-AP (PRDX1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

PRDX1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HepG2 cells using 15816-1-AP (PRDX1 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IGG.

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 15816-1-AP ( PRDX1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 15816-1-AP ( PRDX1 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human brain using 15816-1-AP (PRDX1 antibody) at dilution of 1:25 (under 40x lens).

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human brain using 15816-1-AP (PRDX1 antibody) at dilution of 1:25 (under 10x lens).

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer slide using 15816-1-AP (PRDX1 Antibody) at dilution of 1:50.

PRDX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human breast cancer slide using 15816-1-AP (PRDX1 Antibody) at dilution of 1:50.

PRDX1 Antibody in Western Blot (WB) — A549 cells were subjected to SDS PAGE followed by western blot with (Product # 15816-1-AP) PRDX1 antibody at dilution of 1:10,000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — Rat kidney tissue were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — Raji cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — A549 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP (PRDX1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PRDX1 Antibody in Western Blot (WB) — WB result of PRDX1 antibody (Product # 15816-1-AP) 1:6,000, incubated at room temperature for 1.5 hours with sh-Control and sh-PRDX1 transfected HEK-293 cells.

PRDX1 Antibody in Flow Cytometry (Flow) — 1X10^6 HepG2 cells were stained with 0.2ug PRDX1 antibody (15816-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L) with dilution 1:1500.

PRDX1 Antibody in Immunoprecipitation (IP) — IP result of anti-PRDX1 (IP:15816-1-AP, 3ug; Detection:15816-1-AP 1:1000) with HeLa cells lysate 2400ug.

Product Details

15816-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 26 publications 26 publications

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

-

Immunocytochemistry (ICC/IF)

1:10-1:100

View 6 publications 6 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

-

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Not applicable (N/A)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PRDX1 Fusion Protein Ag8602 (1-199 aa encoded by BC007063)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.14 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSSGNAKIG HPAPNFKATA VMPDGQFKDI SLSDYKGKYV VFFFYPLDFT FVCPTEIIAF SDRAEEFKKL NCQVIGASVD SHFCHLAWVN TPKKQGGLGP MNIPLVSDPK RTIAQDYGVL KADEGISFRG LFIIDDKGIL RQITVNDLPV GRSVDETLRL VQAFQFTDKH GEVCPAGWKP GSDTIKPDVQ KSKEYFSKQK (1-199 aa encoded by BC007063)

Target Information

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.

Cell death & disease

Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X

Sat Apr 08 00:00:00 EDT 2023

EEF1A2 accelerates the protein translation of chemokine in rat myocardial cells induced by ischemia-reperfusion.

Heliyon

Zhang ZJ,Sun ZX,Liu HJ

Sat Apr 01 00:00:00 EDT 2023

Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.

Journal of assisted reproduction and genetics

Zhou M,Guo J,Li S,Li A,Fang Z,Zhao M,Zhang M,Wang X

Sat Jul 01 00:00:00 EDT 2023

Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.

Journal of assisted reproduction and genetics

Zhou M,Guo J,Li S,Li A,Fang Z,Zhao M,Zhang M,Wang X

Sat Jul 01 00:00:00 EDT 2023

Periplocin exerts antitumor activity by regulating Nrf2-mediated signaling pathway in gemcitabine-resistant pancreatic cancer cells.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Bae ES,Byun WS,Ock CW,Kim WK,Park HJ,Lee SK

Sun Jan 01 00:00:00 EST 2023

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Acta pharmacologica Sinica

Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ

Tue Feb 01 00:00:00 EST 2022

Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21.

Free radical biology & medicine

Prutton KM,Marentette JO,Leifheit BA,Esquer H,LaBarbera DV,Anderson CC,Maclean KN,Roede JR

Wed Jun 01 00:00:00 EDT 2022

Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice.

Antioxidants (Basel, Switzerland)

Liu S,Wen X,Huang Q,Zhu M,Lu J

Fri Jun 10 00:00:00 EDT 2022

Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance.

Nature communications

Huang H,Zhang S,Li Y,Liu Z,Mi L,Cai Y,Wang X,Chen L,Ran H,Xiao D,Li F,Wu J,Li T,Han Q,Chen L,Pan X,Li H,Li T,He K,Li A,Zhang X,Zhou T,Xia Q,Man J

Thu Jun 17 00:00:00 EDT 2021

Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment.

Antioxidants & redox signaling

Li J,Cheng P,Li S,Zhao P,Han B,Ren X,Zhong JL,Lloyd MD,Pourzand C,Holmgren A,Lu J

Thu Jun 10 00:00:00 EDT 2021

Maneb alters central carbon metabolism and thiol redox status in a toxicant model of Parkinson's disease.

Free radical biology & medicine

Anderson CC,Marentette JO,Rauniyar AK,Prutton KM,Khatri M,Matheson C,Reisz JA,Reigan P,D'Alessandro A,Roede JR

Fri Jan 01 00:00:00 EST 2021

Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.

International journal of oncology

Ye L,Chen T,Cao J,Sun L,Li W,Zhang C

Sun Nov 01 00:00:00 EDT 2020

MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.

Toxicology and applied pharmacology

Liu T,Guan F,Wang Y,Zhang Z,Li Y,Cui Y,Li Z,Liu H,Zhang Y,Wang Y,Ma S

Fri May 15 00:00:00 EDT 2020

β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.

Aging

Zou K,Li Z,Zhang Y,Mu L,Chen M,Wang R,Deng W,Zou L,Liu J

Wed Dec 09 00:00:00 EST 2020

β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial-mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway.

Aging

Zou K,Li Z,Zhang Y,Mu L,Chen M,Wang R,Deng W,Zou L,Liu J

Wed Dec 09 00:00:00 EST 2020

Direct Proteomic Mapping of Cysteine Persulfidation.

Antioxidants & redox signaling

Fu L,Liu K,He J,Tian C,Yu X,Yang J

Fri Nov 20 00:00:00 EST 2020

Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses.

Scientific reports

Jiang Z,Fu L,Xu Y,Hu X,Yang H,Zhang Y,Luo H,Gan S,Tao L,Liang G,Shen X

Tue Apr 14 00:00:00 EDT 2020

Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses.

Scientific reports

Jiang Z,Fu L,Xu Y,Hu X,Yang H,Zhang Y,Luo H,Gan S,Tao L,Liang G,Shen X

Tue Apr 14 00:00:00 EDT 2020

Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon.

Redox biology

Chowdhury AR,Zielonka J,Kalyanaraman B,Hartley RC,Murphy MP,Avadhani NG

Tue Sep 01 00:00:00 EDT 2020

Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder.

Clinical and experimental immunology

Uzawa A,Mori M,Masuda H,Ohtani R,Uchida T,Aoki R,Kuwabara S

Sun Nov 01 00:00:00 EDT 2020

Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.

BMC ophthalmology

Chen JL,Hung CT,Keller JJ,Lin HC,Wu YJ

Fri Aug 02 00:00:00 EDT 2019

The double inhibition of PDK1 and STAT3-Y705 prevents liver metastasis in colorectal cancer.

Scientific reports

Qin W,Tian Y,Zhang J,Liu W,Zhou Q,Hu S,Yang F,Lu L,Lu H,Cui S,Wen L,Wei S

Tue Sep 10 00:00:00 EDT 2019

Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin.

Cell chemical biology

Zhu H,Wang B,Kong L,An T,Li G,Zhou H,Gong L,Zhao Z,Gong Y,Sun H,Puno P,Li Y

Thu Aug 15 00:00:00 EDT 2019

MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation.

World journal of gastroenterology

Zhang Z,Dai DQ

Thu Mar 14 00:00:00 EDT 2019

Luteolin ameliorates rat myocardial ischaemia-reperfusion injury through activation of peroxiredoxin II.

British journal of pharmacology

Wei B,Lin Q,Ji YG,Zhao YC,Ding LN,Zhou WJ,Zhang LH,Gao CY,Zhao W

Wed Aug 01 00:00:00 EDT 2018

Luteolin ameliorates rat myocardial ischaemia-reperfusion injury through activation of peroxiredoxin II.

British journal of pharmacology

Wei B,Lin Q,Ji YG,Zhao YC,Ding LN,Zhou WJ,Zhang LH,Gao CY,Zhao W

Wed Aug 01 00:00:00 EDT 2018

Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.

Journal of cellular biochemistry

Liu GY,Shi JX,Shi SL,Liu F,Rui G,Li X,Gao LB,Deng XL,Li QF

Fri Dec 01 00:00:00 EST 2017

Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.

Journal of cellular biochemistry

Liu GY,Shi JX,Shi SL,Liu F,Rui G,Li X,Gao LB,Deng XL,Li QF

Fri Dec 01 00:00:00 EST 2017

Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.

Journal of cellular biochemistry

Liu GY,Shi JX,Shi SL,Liu F,Rui G,Li X,Gao LB,Deng XL,Li QF

Fri Dec 01 00:00:00 EST 2017

Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.

Journal of cellular biochemistry

Liu GY,Shi JX,Shi SL,Liu F,Rui G,Li X,Gao LB,Deng XL,Li QF

Fri Dec 01 00:00:00 EST 2017

Inhibition of HDAC6 increases acetylation of peroxiredoxin1/2 and ameliorates 6-OHDA induced dopaminergic injury.

Neuroscience letters

Jian W,Wei X,Chen L,Wang Z,Sun Y,Zhu S,Lou H,Yan S,Li X,Zhou J,Zhang B

Fri Sep 29 00:00:00 EDT 2017

Inhibition of HDAC6 increases acetylation of peroxiredoxin1/2 and ameliorates 6-OHDA induced dopaminergic injury.

Neuroscience letters

Jian W,Wei X,Chen L,Wang Z,Sun Y,Zhu S,Lou H,Yan S,Li X,Zhou J,Zhang B

Fri Sep 29 00:00:00 EDT 2017

The role of peroxiredoxin I in cisplatin-induced ototoxicity.

Auris, nasus, larynx

Le Q,Tabuchi K,Warabi E,Hara A

Sat Apr 01 00:00:00 EDT 2017

The role of peroxiredoxin I in cisplatin-induced ototoxicity.

Auris, nasus, larynx

Le Q,Tabuchi K,Warabi E,Hara A

Sat Apr 01 00:00:00 EDT 2017

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.

Free radical biology & medicine

Dong K,Wu M,Liu X,Huang Y,Zhang D,Wang Y,Yan LJ,Shi D

Thu Dec 01 00:00:00 EST 2016

Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.

Free radical biology & medicine

Dong K,Wu M,Liu X,Huang Y,Zhang D,Wang Y,Yan LJ,Shi D

Thu Dec 01 00:00:00 EST 2016

Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.

Journal of agricultural and food chemistry

Liu C,Lin JJ,Yang ZY,Tsai CC,Hsu JL,Wu YJ

Wed Dec 03 00:00:00 EST 2014

Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.

Journal of agricultural and food chemistry

Liu C,Lin JJ,Yang ZY,Tsai CC,Hsu JL,Wu YJ

Wed Dec 03 00:00:00 EST 2014

The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.

Cell reports

Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D

Thu May 30 00:00:00 EDT 2013

The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.

Cell reports

Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D

Thu May 30 00:00:00 EDT 2013

Identification of human host proteins contributing to H5N1 influenza virus propagation by membrane proteomics.

Journal of proteome research

Liu C,Zhang A,Guo J,Yang J,Zhou H,Chen H,Jin M

Fri Nov 02 00:00:00 EDT 2012

Identification of human host proteins contributing to H5N1 influenza virus propagation by membrane proteomics.

Journal of proteome research

Liu C,Zhang A,Guo J,Yang J,Zhou H,Chen H,Jin M

Fri Nov 02 00:00:00 EDT 2012

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.

Toxicology letters

Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J

Tue Oct 02 00:00:00 EDT 2012

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.

Toxicology letters

Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J

Tue Oct 02 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: ACR1; Alu co-repressor 1; B166; HBP23; Heme-binding 23 kDa protein; macrophage 23 Kd stress protein; Macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NKEF-A; OSF-3; osteoblast specific factor 3; Osteoblast-specific factor 3; PAG; Peroxiredoxin-1; proliferation-associated gene A; Proliferation-associated gene protein; Prx 1; thioredoxin dependent peroxide reductase 2; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1; Trx dependent peroxide reductase 2

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Gene Aliases: Hbp23; MSP23; NKEF-A; NKEFA; OSF-3; OSF3; PAG; PAGA; PAGB; PRDX1; PrdxI; PRX1; PRXI; TDPX2; TDX2; TPxA

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UniProt ID: (Human) Q06830, (Mouse) P35700, (Rat) Q63716

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Entrez Gene ID: (Human) 5052, (Mouse) 18477, (Rat) 117254

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peroxidase activity protein binding thioredoxin peroxidase activity identical protein binding poly(A) RNA binding cadherin binding involved in cell-cell adhesion antioxidant activity oxidoreductase activity heme binding protein homodimerization activity peroxiredoxin activity peroxidase

Process(es)

response to reactive oxygen species skeletal system development retina homeostasis cell proliferation removal of superoxide radicals regulation of stress-activated MAPK cascade erythrocyte homeostasis natural killer cell mediated cytotoxicity regulation of NF-kappaB import into nucleus hydrogen peroxide catabolic process cell redox homeostasis oxidation-reduction process cell-cell adhesion response to oxidative stress

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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