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Product Details
13585-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRDX6 Fusion Protein Ag4512 (1-224 aa encoded by BC035857)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPGGLLLGD VAPNFEANTT VGRIRFHDFL GDSWGILFSH PRDFTPVCTT ELGRAAKLAP EFAKRNVKLI ALSIDSVEDH LAWSKDINAY NCEEPTEKLP FPIIDDRNRE LAILLGMLDP AEKDEKGMPV TARVVFVFGP DKKLKLSILY PATTGRNFDE ILRVVISLQL TAEKRVATPV DWKDGDSVMV LPTIPEEEAK KLFPKGVFTK ELPSGKKYLR YTPQP (1-224 aa encoded by BC035857)
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; epididymis secretory sperm binding protein Li 128m; Glutathione-dependent peroxiredoxin; Liver 2D page spot 40; LPC acyltransferase 5; Lysophosphatidylcholine acyltransferase 5; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; PAGA; PAGB; Peroxiredoxin-6; Prx6; Red blood cells page spot 12; Thiol-specific antioxidant protein
Gene Aliases: 1-Cys; 1-Cys Prx; 1-cysPrx; 9430088D19Rik; AA690119; Aipla2; AOP2; Brp-12; CP-3; GPx; HEL-S-128m; KIAA0106; Ltw-4; Ltw4; Lvtw-4; NSGPx; ORF06; p29; Prdx5; PRDX6; PRX; Tsa
UniProt ID: (Human) P30041, (Mouse) O08709, (Rat) O35244
Entrez Gene ID: (Human) 9588, (Mouse) 11758, (Rat) 94167
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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