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Immunogen sequence: SLSISVSNS QIQENVDIAT VYQIFPDEVL GSGQFGVVYG GKHRKTGRDV AVKVIDKLRF PTKQESQLRN EVAILQSLRH PGIVNLECMF ETPEKVFVVM EKLHGDMLEM ILSSEKGRLP ERLTKFLITQ ILVALRHLHF KNIVHCDLKP ENVLLASADP FPQVKLCDFG FARIIGEKSF RRSVVGTPAY LAPEVLLNQG YNRSLDMWSV GVIMYVSLSG TFPFNEDEDI NDQIQNAAFM YPASPWSHIS AGAIDLINNL LQVKMRKRYS VDKSLSHPWL QEYQTWLDLR ELEGKMGERY ITHESDDARW EQFAAEHPLP GSGLPTDRDL GGACPPQDHD MQGLAERISV L (189-538 aa encoded by BC025307)
PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: nPKC-D2; Serine/threonine-protein kinase D2
Gene Aliases: AI325941; HSPC187; nPKC-D2; PKD2; PRKD2; RGD1308054
UniProt ID: (Human) Q9BZL6, (Rat) Q5XIS9, (Mouse) Q8BZ03
Entrez Gene ID: (Human) 25865, (Rat) 292658, (Mouse) 101540
Molecular Function: non-receptor serine/threonine protein kinase
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