Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: GSHYTSPSEN MWNTGSTYNL SSGMAVAGMP TAYDLSSVIA SGSSVGHNNL IPLANTGIVN HTHSRMGSIM STGIVQGSSG AQGSGGGSTS AHYAVNSQFT MGGPAISMAS PMSIPTNT
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; Histone-arginine methyltransferase CARM1; protein arginine methyltransferase; Protein arginine N-methyltransferase 4
Gene Aliases: CARM1; PRMT4
UniProt ID: (Human) Q86X55, (Mouse) Q9WVG6, (Rat) Q4AE70
Entrez Gene ID: (Human) 10498, (Mouse) 59035, (Rat) 363026
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